Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PSN 375963 (PSN 375963 hydrochloride) hydrochloride is a synthetic agonist of the endogenous ligand for GPR119.
説明 | PSN 375963 (PSN 375963 hydrochloride) hydrochloride is a synthetic agonist of the endogenous ligand for GPR119. |
ターゲット&IC50 | GPR119:7.9 μM(EC50,mouse), GPR119:8.4(EC50,human) |
In vitro | PSN 375963 is a potent GPR119 agonist with EC50s of 8.4 and 7.9 μM for human and mouse GPR119[1]. |
In vivo | PSN 375963 suppressed food intake in rats and reduced body weight gain and white adipose tissue deposition upon subchronic oral administration to high-fat-fed rats[2]. |
別名 | PSN 375963 hydrochloride |
分子量 | 285.38 |
分子式 | C17H23N3O |
CAS No. | 388575-52-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4 mg/ml(12.43 mM)
Ethanol: 24 mg/ml(74.57 mM)
You can also refer to dose conversion for different animals. 詳細
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PSN 375963 388575-52-8 Endocrinology/Hormones GPCR/G Protein GPR Inhibitor inhibit PSN 375963 Hydrochloride receptor PSN-375963 G Protein-Coupled Receptor 119 endogenous PSN 375963 hydrochloride GPR119 PSN375963 Hydrochloride PSN-375963 Hydrochloride ligand PSN375963 orphan cAMP inhibitor