Powder: -20°C for 3 years | In solvent: -80°C for 1 year
9-hydroxy Stearic Acid is a hydroxy fatty acid that is the active metabolite of 9-PAHSA. 9-hydroxy Stearic Acid is formed from 9-PAHSA through carboxyl ester lipase in the liver and pancreas. The 9-hydroxy Stearic Acid (5 μM) was stearic acid, which inhibited the expression of histone deacetylase 1 (HDAC1) in the lysate of HT-29 colon cancer cells. 3. When the concentration was 100 μM.1, the proliferation of HT-29 cells was inhibited and cell cycle arrest was induced in G0/ g1 phase.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 9,000 | |||
5 mg | 在庫あり | ¥ 39,500 | |||
10 mg | 在庫あり | ¥ 68,500 | |||
25 mg | 在庫あり | ¥ 113,000 | |||
50 mg | 在庫あり | ¥ 165,000 | |||
100 mg | 在庫あり | ¥ 226,500 |
説明 | 9-hydroxy Stearic Acid is a hydroxy fatty acid that is the active metabolite of 9-PAHSA. 9-hydroxy Stearic Acid is formed from 9-PAHSA through carboxyl ester lipase in the liver and pancreas. The 9-hydroxy Stearic Acid (5 μM) was stearic acid, which inhibited the expression of histone deacetylase 1 (HDAC1) in the lysate of HT-29 colon cancer cells. 3. When the concentration was 100 μM.1, the proliferation of HT-29 cells was inhibited and cell cycle arrest was induced in G0/ g1 phase. |
In vitro |
9-hydroxy Stearic acid is a hydroxy fatty acid and an active metabolite of 9-PAHSA .[1][2] It is formed from 9-PAHSA by liver and pancreatic carboxyl ester lipases.2 9-hydroxy Stearic acid (5 µM) inhibits histone deacetylase 1 (HDAC1) in HT-29 colon cancer cell lysates.[3] It inhibits the proliferation of, and induces cell cycle arrest at the G0/G1 phase in, HT-29 cells when used at a concentration of 100 µM.1.[1] |
分子量 | 300.48 |
分子式 | C18H36O3 |
CAS No. | 3384-24-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (199.68 mM)
Chloroform: Soluble
You can also refer to dose conversion for different animals. 詳細
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9-hydroxy Stearic Acid 3384-24-5 Chromatin/Epigenetic DNA Damage/DNA Repair HDAC 9 hydroxy Stearic Acid 9hydroxy Stearic Acid Inhibitor inhibitor inhibit