Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ACY-957 (HDAC Inhibitor C001) is an orally active and selective inhibitor of HDAC1 and HDAC2 (IC50s: 7 nM, 18 nM, and 1300 nM against HDAC1/2/3) and shows no inhibition on HDAC4/5/6/7/8/9.
説明 | ACY-957 (HDAC Inhibitor C001) is an orally active and selective inhibitor of HDAC1 and HDAC2 (IC50s: 7 nM, 18 nM, and 1300 nM against HDAC1/2/3) and shows no inhibition on HDAC4/5/6/7/8/9. |
ターゲット&IC50 | HDAC1:7 nM, HDAC3:1300 nM, HDAC2:18 nM |
In vitro | ACY-957 is a selective inhibitor of HDAC1 and HDAC2, with IC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9. ACY-957 has an IC50 of 304 nM for HDAC2 in primary hematopoietic progenitors[1]. |
別名 | HDAC Inhibitor C001 |
分子量 | 429.54 |
分子式 | C24H23N5OS |
CAS No. | 1609389-52-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 76.5 mg/mL (178.1 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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ACY-957 1609389-52-7 Chromatin/Epigenetic DNA Damage/DNA Repair HDAC ACY 957 ACY957 HDAC Inhibitor C001 HDAC Inhibitor C 001 HDAC Inhibitor C-001 Inhibitor inhibitor inhibit