Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ansamitocin p-3 (Maytansinol isobutyrate) is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization.
説明 | Ansamitocin p-3 (Maytansinol isobutyrate) is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization. |
In vitro | Ansamitocin p-3 inhibits the proliferation in a concentration-dependent manner with IC50s of 20, 50, 140, and 150 pM for MCF-7, HeLa, EMT-6/AR1, and MDA-MB-231 cells in culture, respectively. Ansamitocin P3 binds to purified tubulin (Kd = 1.3 µM)[1]. |
別名 | Maytansinol isobutyrate, Antibiotic C 15003P3, NSC292222 |
分子量 | 635.14 |
分子式 | C32H43ClN2O9 |
CAS No. | 66584-72-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (141.7 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Ansamitocin p-3 66584-72-3 Cytoskeletal Signaling Microtubule Associated Maytansinol isobutyrate NSC-292222 NSC 292222 Antibiotic C 15003P3 NSC292222 Maytansinol Isobutyrate Inhibitor inhibitor inhibit