Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Azathramycin (Desmethyl Azithromycin) is an antibiotic derived from erythromycin, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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25 mg | 在庫あり | ¥ 7,000 | |||
50 mg | 在庫あり | ¥ 9,500 | |||
100 mg | 在庫あり | ¥ 13,000 | |||
200 mg | 在庫あり | ¥ 18,500 | |||
500 mg | 在庫あり | ¥ 30,500 | |||
1 g | 在庫あり | ¥ 45,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 9,000 |
説明 | Azathramycin (Desmethyl Azithromycin) is an antibiotic derived from erythromycin, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA. |
細胞研究 | THP-1 cells (106 cells in 1 mL RPMI medium, without antibiotics, growth factors or serum) are seeded in each well of 24-well plates and allowed to settle for 1 hour. Next, 50 μL of the test compound is added followed by 50 μL of LPS (final concentration of 10 μg/mL). After 24h (37°C and 5% CO2) the supernatants and cell pellets are collected (1200 rpm, 5 min). THP-1 cell viability is tested using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT). MTT is dissolved at 2 mg/mL in PBS and aliquots are stored at -20°C. The MTT assay is performed according to the suppliers instructions. Absorbance of MTT converted into formazan is measured at a wavelength of 570 nm with background subtraction at 630 nm. |
別名 | Desmethyl Azithromycin, 6-Demethylazithromycin, Azaerythromycin A, Azaerythromycin |
分子量 | 734.96 |
分子式 | C37H70N2O12 |
CAS No. | 76801-85-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 7.35 mg/mL (10 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Azathramycin 76801-85-9 Microbiology/Virology Antibacterial Antibiotic Desmethyl Azithromycin Bacterial 6-Demethylazithromycin inhibit Azaerythromycin A Azaerythromycin Inhibitor inhibitor