Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
50 mg | 在庫あり | ¥ 8,500 | |||
100 mg | 在庫あり | ¥ 12,000 | |||
200 mg | 在庫あり | ¥ 16,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. |
ターゲット&IC50 | α7 nAChR:122 nM, α4β2 nAChR:49 nM |
In vitro | Administered in SCID mice bearing human laryngeal squamous cell carcinoma tumors, Benzethonium chloride (5 mg/kg) inhibited the growth of xenografts. |
In vivo | In human hypopharyngeal squamous carcinoma cells, Benzethonium chloride at a concentration of 9 µM induces apoptosis and activates caspases after 12 hours. Furthermore, Benzethonium chloride at 5 µM enhances the effect of glucose consumption on the intracellular solute Ca(2+) concentration and its binding to membrane-associated proteins. |
細胞研究 | Cells are seeded in 96-well plates at 5,000 per well in 100 μL of growth medium and allowed to incubate for 24 hours. Benzethonium chloride is then added, as indicated, in a total volume of 5 μL. After 48 hours, MTS assay is done according to the specifications of the manufacturer, with DMSO (0.1%)–treated cells as negative control and cisplatin (166.6 μM)–treated cells as positive control.(Only for Reference) |
別名 | Hyamine, Phemeride, Quatrachlor |
分子量 | 448.09 |
分子式 | C27H42ClNO2 |
CAS No. | 121-54-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.4 mg/mL (49.99 mM)
H2O: 83 mg/mL (185.2 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Benzethonium chloride 121-54-0 Neuroscience AChR Hyamine Nicotinic acetylcholine receptors Inhibitor Phemeride Benzethonium nAChR inhibit Benzethonium Chloride Quatrachlor inhibitor