Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bilastine (Bilaxten) is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
25 mg | 在庫あり | ¥ 9,000 | |||
50 mg | 在庫あり | ¥ 15,000 | |||
100 mg | 在庫あり | ¥ 24,000 | |||
200 mg | 在庫あり | ¥ 35,500 | |||
500 mg | 在庫あり | ¥ 60,500 |
説明 | Bilastine (Bilaxten) is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action. |
ターゲット&IC50 | H1 receptor(guinea-pig cerebellum):44.15 nM(Ki) |
In vitro | Bilastine has a highly selective affinity for the H1-receptor but a very low affinity for 30 other tested receptors. It isn't obvious inhibitory against bradykinin, serotonin, muscarinic M3-receptors, leukotriene D4, calcium, α1-adrenoceptors, β2-adrenoceptors, and H2- and H3- receptors. |
In vivo | In patients with allergic rhinoconjunctivitis, Bilastine is efficacious in all nasal symptoms including obstruction and in eye symptoms. In the fasting state, Bilastine is quickly absorbed, but the absorption is slowed when it is taken with food or fruit juice. |
別名 | Bilaxten |
分子量 | 463.61 |
分子式 | C28H37N3O3 |
CAS No. | 202189-78-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Slightly soluble
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Bilastine 202189-78-4 GPCR/G Protein Immunology/Inflammation Neuroscience Histamine Receptor Inhibitor inhibit Bilaxten inhibitor