Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mizolastine (SL 850324) (IC50= 47 nM) is a histamine H1-receptor antagonist.It is used in the treatment of allergic reactions such as hay fever (seasonal allergic rhinitis), hives.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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10 mg | 在庫あり | ¥ 8,000 | |||
25 mg | 在庫あり | ¥ 12,500 | |||
50 mg | 在庫あり | ¥ 16,000 | |||
100 mg | 在庫あり | ¥ 22,500 | |||
200 mg | 在庫あり | ¥ 43,000 | |||
500 mg | 在庫あり | ¥ 72,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 8,500 |
説明 | Mizolastine (SL 850324) (IC50= 47 nM) is a histamine H1-receptor antagonist.It is used in the treatment of allergic reactions such as hay fever (seasonal allergic rhinitis), hives. |
ターゲット&IC50 | H1 receptor:47 nM |
キナーゼ試験 | ssay for cytokines: The cultures for cytokine production are set up at 37 °C as follows: the mixtures of SN-4 and autologous APC (each 1 × 105 cells/well) are cultured for 3 days with 50 μg/mL of Cry j1 in a total volume of 0.2 mL in round-bottomed micro plates; PBMC (2 × 10 5 cells/well) from normal donors are cultured for 24 hours with 10 μg/ml of PHA in a total volume of 0.2 mL in flat-bottomed, 96-well micro plates; and purified T cells (1 × 105 cells/well) from normal donors are cultured in a total volume of 1 ml for 24 hours with anti-CD3 mAb that have been immobilized on flat-bottomed, 24-well plates at a concentration of 5 μg/ml. Cytokines in the culture supernatants are quantitatively assayed by the following commercially available kits: IL-4 and IFN-γ. The sensitivity of the assay is 30 pg/mL for IL-4 and 1 U/mL for IFN-γ. |
別名 | SL 850324 |
分子量 | 432.49 |
分子式 | C24H25FN6O |
CAS No. | 108612-45-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12 mg/mL (27.75 mM)
You can also refer to dose conversion for different animals. 詳細
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Mizolastine 108612-45-9 GPCR/G Protein Immunology/Inflammation Neuroscience Histamine Receptor mast cells SL-850324 second generation antihistamine SL850324 SL 850324 allergic rhinitis inhibit chronic idiopathic urticarial Inhibitor inhibitor