Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 7,500 | |||
2 mg | 在庫あり | ¥ 10,000 | |||
5 mg | 在庫あり | ¥ 16,500 | |||
10 mg | 在庫あり | ¥ 29,500 | |||
25 mg | 在庫あり | ¥ 62,000 | |||
50 mg | 在庫あり | ¥ 118,000 | |||
100 mg | 在庫あり | ¥ 171,500 |
説明 | CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK). |
ターゲット&IC50 | FAK:2.3 nM, ALK:120 nM |
キナーゼ試験 | Kinase assay: Inhibitory potency of GSK2656157 is measured using recombinant GST-PERK (536–1116 amino acids) with 6-His-full-length human eIF2a as a substrate. Kinase selectivity is evaluated using 27 kinases at GSK as well as a panel of 300 kinases. |
別名 | CEP37440 |
分子量 | 580.12 |
分子式 | C30H38ClN7O3 |
CAS No. | 1391712-60-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 2.2 mg/mL (3.79 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CEP-37440 1391712-60-9 Angiogenesis Cytoskeletal Signaling Tyrosine Kinase/Adaptors ALK FAK inhibit Inhibitor CEP 37440 Cluster of differentiation 246 PTK2 triple-negative breast cancer inflammatory breast cancer Anaplastic lymphoma kinase FAK1 Anaplastic lymphoma kinase (ALK) Focal adhesion kinase CEP37440 PTK2 protein tyrosine kinase 2 autophosphorylation kinase CD246 ALK tyrosine kinase receptor inhibitor