Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cilostazol (OPC 21) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of cilostazol is as a Phosphodiesterase 3 Inhibitor.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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25 mg | 在庫あり | ¥ 9,000 | |||
50 mg | 在庫あり | ¥ 12,500 | |||
100 mg | 在庫あり | ¥ 18,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 13,000 |
説明 | Cilostazol (OPC 21) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of cilostazol is as a Phosphodiesterase 3 Inhibitor. |
ターゲット&IC50 | PDE3:0.2 μM |
In vivo | Cilostazol induces relaxation of vascular smooth muscle and causes vasodilation. It inhibits the expression of monocyte chemotactic protein-1 (MCP-1) induced by cytokines. Additionally, Cilostazol reduces plasma triglycerides and increases high-density lipoprotein (HDL) levels. The vasodilatory and antithrombotic effects of Cilostazol are primarily due to the inhibition of phosphodiesterase 3 (PDE3) and the subsequent elevation of intracellular cyclic adenosine monophosphate (cAMP) levels. It also inhibits platelet aggregation and adenosine uptake. |
別名 | OPC 21, OPC 13013 |
分子量 | 369.46 |
分子式 | C20H27N5O2 |
CAS No. | 73963-72-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 15 mg/mL (40.6 mM), Sonication is recommended.
Ethanol: 3.7 mg/mL (10 mM)
You can also refer to dose conversion for different animals. 詳細
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Cilostazol 73963-72-1 Autophagy Metabolism PDE OPC-21 late fibrogenesis OPC-13013 cardiovascular inhibit OPC21 OPC 21 injury hepatic OPC13013 Phosphodiesterase (PDE) OPC 13013 Inhibitor inhibitor