Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Citalopram (Lu 10-171 is an orally active, selective serotonin reuptake inhibitor (SSRI), a selective 5-hydroxytryptamine reuptake inhibitor, and a racemic mixture of the S(+)-enantiomer (Escitalopram) and the R(-)-enantiomer.Citalopram exhibits antidepressant activity and enhances serotonergic neurotransmission. It can be used to study Alzheimer's disease.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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25 mg | 在庫あり | ¥ 7,000 | |||
50 mg | 在庫あり | ¥ 9,500 | |||
100 mg | 在庫あり | ¥ 15,000 | |||
500 mg | 在庫あり | ¥ 35,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 10,500 |
説明 | Citalopram (Lu 10-171 is an orally active, selective serotonin reuptake inhibitor (SSRI), a selective 5-hydroxytryptamine reuptake inhibitor, and a racemic mixture of the S(+)-enantiomer (Escitalopram) and the R(-)-enantiomer.Citalopram exhibits antidepressant activity and enhances serotonergic neurotransmission. It can be used to study Alzheimer's disease. |
In vitro | Citalopram exhibits concentration-dependent cytotoxicity when applied at concentrations ranging from 25 to 175 μM for 24 hours[4]. Specifically, at a concentration of 100 μM for 24 hours, Citalopram strongly downregulates the expression of MYBL2, BIRC5, BARD1, AURKA, CCNA2, and CCNE1 in B104 cells[4]. |
In vivo | Administered via intraperitoneal injection at doses ranging from 5 to 40 mg/kg, Citalopram reduces immobility time in DBA/2J mice but does not elicit a similar effect in C57BL/6J mice[3]. |
別名 | Cipram, Lu 10-171, Lu-10-171 Lu10-171 |
分子量 | 324.39 |
分子式 | C20H21FN2O |
CAS No. | 59729-33-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL(246.62 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Citalopram 59729-33-8 GPCR/G Protein Neuroscience 5-HT Receptor Cipram Lu 10-171 Lu-10-171 Lu10-171 Inhibitor inhibitor inhibit