Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMH25 is a novel covalent and potent inhibitor of mTOR and shows in vivo antitumor activity against triple-negative breast cancer cells.
説明 | DMH25 is a novel covalent and potent inhibitor of mTOR and shows in vivo antitumor activity against triple-negative breast cancer cells. |
In vivo | In vivo, DHM25 was an efficient inhibitor of growth and metastasis of triple-negative breast cancer cells, paving the way for its clinical application in oncology. Constitutive activation of the PI3K/mTOR signaling pathway contributes to carcinogenesis and metastasis in most, if not all, breast cancers. |
分子量 | 489.94 |
分子式 | C15H8Br3NO3 |
CAS No. | 1685280-21-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (51.03 mM)
You can also refer to dose conversion for different animals. 詳細
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DMH-25 1685280-21-0 PI3K/Akt/mTOR signaling mTOR DMH 25 DMH25 Inhibitor inhibitor inhibit