keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dabrafenib Mesylate (GSK2118436 Mesylate) is a B-Raf inhibitor(IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 9,500 | |||
10 mg | 在庫あり | ¥ 13,000 | |||
25 mg | 在庫あり | ¥ 16,500 | |||
50 mg | 在庫あり | ¥ 19,500 | |||
100 mg | 在庫あり | ¥ 27,000 | |||
500 mg | 在庫あり | ¥ 55,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 13,000 |
説明 | Dabrafenib Mesylate (GSK2118436 Mesylate) is a B-Raf inhibitor(IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively). |
ターゲット&IC50 | B-Raf (V600E):0.6 nM, Raf:5 nM |
In vitro | In human endothelial cells, Dabrafenib inhibits the release of HMGB1 and down-regulates the HMGB1-dependent inflammatory response by enhancing the expression of cell adhesion molecules (CAM)[1] |
別名 | GSK 2118436B, GSK2118436 Mesylate |
分子量 | 615.67 |
分子式 | C24H24F3N5O5S3 |
CAS No. | 1195768-06-9 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 34 mg/mL (55.22 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Dabrafenib Mesylate 1195768-06-9 MAPK Raf Dabrafenib Raf kinases GSK 2118436B Inhibitor GSK2118436 inhibit GSK 2118436 Mesylate GSK2118436 Mesylate GSK 2118436 GSK-2118436 GSK-2118436 Mesylate inhibitor