Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and is a weak non-ergoline dopamine agonist.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 10,000 | |||
10 mg | 在庫あり | ¥ 16,500 | |||
25 mg | 在庫あり | ¥ 35,500 | |||
50 mg | 在庫あり | ¥ 60,500 | |||
100 mg | 在庫あり | ¥ 91,500 | |||
200 mg | 在庫あり | ¥ 133,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,000 |
説明 | Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and is a weak non-ergoline dopamine agonist. |
In vitro | Dextromethorphan has been found to have neuroprotective effects and is being studied for the treatment of amyotrophic lateral sclerosis (ALS). Dexpramipexole reduces mitochondrial reactive oxygen species (ROS) production, inhibits the activation of apoptosis pathways, and improves cell survival in response to various neurotoxins and β-amyloid neurotoxicity. Compared with the S-(-) isomer, dextromethorphan has lower dopamine agonist activity. |
別名 | KNS-760704 dihydrochloride, R-(+)-Pramipexole dihydrochloride, (R)-Pramipexole dihydrochloride |
分子量 | 284.25 |
分子式 | C10H19Cl2N3S |
CAS No. | 104632-27-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (351.80 mM)
H2O: 100 mg/mL (351.80 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Dexpramipexole dihydrochloride 104632-27-1 GPCR/G Protein Neuroscience Dopamine Receptor inhibit Inhibitor KNS 760704 Dihydrochloride KNS-760704 Dihydrochloride (R)-Pramipexole KNS760704 KNS-760704 dihydrochloride R-(+)-Pramipexole dihydrochloride R-Pramipexole Dihydrochloride Pramipexole Dexpramipexole KNS 760704 Pramipexole Dihydrochloride KNS760704 Dihydrochloride Dexpramipexole Dihydrochloride (R)-Pramipexole dihydrochloride R-Pramipexole KNS-760704 inhibitor