Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Echinatin (Retrochalcone) disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria, inhibits DNP-ATPase activity while stimulating range latent ATPase activity. Echinatin has significant antioxidant activities, it shows strong scavenging activity toward the ABTS + radical, it also dose-dependently inhibits LPS induced reactive oxygen species (ROS) production in RAW 264.7 cells and inhibits the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells.
説明 | Echinatin (Retrochalcone) disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria, inhibits DNP-ATPase activity while stimulating range latent ATPase activity. Echinatin has significant antioxidant activities, it shows strong scavenging activity toward the ABTS + radical, it also dose-dependently inhibits LPS induced reactive oxygen species (ROS) production in RAW 264.7 cells and inhibits the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells. |
植物由来 |
別名 | Retrochalcone |
分子量 | 270.28 |
分子式 | C16H14O4 |
CAS No. | 34221-41-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5% DMSO+95% Saline: 2.45 mg/mL (9.06 mM, suspension)
Chloroform: Soluble
DMSO: 20 mg/mL (74 mM)
You can also refer to dose conversion for different animals. 詳細
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Echinatin 34221-41-5 oxidation-reduction Free radical scavengers Retrochalcone inhibit Inhibitor inhibitor