Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside has anti-inflammatory activities and also may have significant therapeutic benefits against diabetic complications and atherosclerosis.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 34,000 | |||
5 mg | 在庫あり | ¥ 84,500 | |||
10 mg | 在庫あり | ¥ 126,500 | |||
25 mg | 在庫あり | ¥ 203,500 | |||
50 mg | 在庫あり | ¥ 280,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 89,500 |
説明 | Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside has anti-inflammatory activities and also may have significant therapeutic benefits against diabetic complications and atherosclerosis. |
In vitro | Emodin-6-O-β-D-glucoside (EG) is a new active compound from Reynoutria japonica. EG was found to suppress the release of HMGB1, the production of tumor necrosis factor (TNF)-α, and the activation of nuclear factor-κB (NF-κB) by HMGB1 in HUVECs |
In vivo | Emodin-6-O-β-D-glucoside (EG) also inhibit HMGB1-mediated hyperpermeability and leukocyte migration in mice. Furthermore, EG also increased the survival times of CLP administered mice. |
別名 | Glucoemodin |
分子量 | 432.38 |
分子式 | C21H20O10 |
CAS No. | 34298-85-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 65 mg/ml (150.33 mM)
You can also refer to dose conversion for different animals. 詳細
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Emodin 6-O-β-D-glucoside 34298-85-6 Others atherosclerosis Emodin 6OβDglucoside Emodin 6-O-beta-D-glucoside diabetic Reynoutria active Inhibitor Emodin 6-O-b-D-glucoside barrier complications Glucoemodin potent japonica protective anti-inflammatory Emodin 6 O β D glucoside inhibit inhibitor