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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TP1555L1 | Fibronectin Active Fragment Control acetate | Fibronectin Active Fragment Control acetate(97461-84-2 Free base) | |
Fibronectin Active Fragment Control acetate is an active fragment of fibronectin which is a glycoprotein. | |||
T5401 | GSK2983559 active metabolite | GSK2983559,RIPK2 inhibitor 1,RIPK2-IN-1 | RIP kinase |
GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor. | |||
TP1555 | Fibronectin Active Fragment Control | ||
Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins.In addition to integrins, fibronectin also binds extracellular matrix ... | |||
T14122 | Active-mono-sulfone-PEG8-acid | Others | |
Active-mono-sulfone-PEG8-acid is a polyethylene glycol (PEG) derivative serving as a linker for PROTAC synthesis[1]. | |||
T10480 | Bay 41-4109 (less active enantiomer) | HBV | |
Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent HBV inhibitor (IC50: 53 nM). | |||
T19667 | R-138727 | Prasugrel active metabolite | |
R-138727 is a novel P2Y12 receptor inhibitor. | |||
T29705 | AG-2000 Free Base | Lansoprazole sulfenamide active metabolite | |
AG-2000 Free Base is a bio-active chemical. Detailed information has not been published. | |||
T13646 | Desisobutyryl-ciclesonide | CIC-AP,Ciclesonide active principle | Others |
Desisobutyryl-ciclesonide has an affinity for glucocorticoid receptors. Desisobutyryl-ciclesonide is the active metabolite of Ciclesonide. | |||
T29704 | AG-1812 free base | UNII-6RI44GB0V9,HE078804,AC1MIZB6,Lansoprazole disulfide active metabolite | |
ABT-1812 is a bio-active chemical. | |||
T9966 | GSK-1520489A | Wee1 | |
GSK-1520489A is an active PKMYT1 inhibitor. | |||
T8348 | Phentolamine | Adrenergic Receptor | |
Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist | |||
T8580 | Bupranolol | Adrenergic Receptor | |
Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic. | |||
T9565 | OSBPL7-IN-1 | Others | |
OSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression[1]. | |||
T9732 | VY-3-135 | Fatty Acid Synthase | |
VY-3-135 is a metastasis inhibitor and an acetyl-CoA synthetase 2 (ACSS2) modulator. | |||
T1292 | Tiapride hydrochloride | Dopamine Receptor | |
Tiapride is a selective blocker of D2/3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing dyskinesia, negative symptoms of psychosis, alcohol withdraw... | |||
T8734 | Choline | Others | |
Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins | |||
T20525 | Chloramphenicol palmitate | Antibacterial , Antibiotic | |
Chloramphenicol palmitate is a broad-spectrum antibiotic with activity against gram-positive and gram-negative bacteria. Chloramphenicol palmitate can be used in studies about acting as a bacterial selection agent in tra... | |||
T34896 | Tofisopam | Emandaxin,Grandaxin | Others |
Tofisopam (Grandaxin) is a 2,3-benzodiazepine compound with anxiolytic activity that can be taken orally. | |||
T40732 | TMPD dihydrochloride | ||
TMPD dihydrochloride is an active substrate of enzymatically convert redox and an electron donor for the reduction of heme peroxidases. | |||
T9805 | BAY 2666605 | PDE | |
BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects. | |||
T11689 | ITI-214 | ITI214 | PDE |
ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = ... | |||
T9164 | BMS-986242 | BMS986242 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer. | |||
T9590 | T-1095 | SGLT , transporter | |
T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2). | |||
T2629 | UNC2881 | TAM Receptor | |
UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively. | |||
T9977 | SGK1-IN-4 | SGK | |
SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis. | |||
T7686 | Ramiprilat | RAAS | |
Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. | |||
T8581 | Flecainide hydrochloride | Others | |
Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias. | |||
T9303 | MRTX1133 | Ras | |
MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors. | |||
T36670 | JNJ-67856633 | MALT | |
JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease . JNJ-67856633 lead to tumor stasis in some cases. | |||
T2678 | LB42708 | Transferase | |
T17158 | Trans-AUCB | t-AUCB | Epoxide Hydrolase |
trans-AUCB (t-AUCB) is an effective and selective soluble epoxide hydrolase inhibitor (IC50s: 1.3 nM, 8 nM, 8 nM for hsEH, mouse sEH and rat sEH, respectively). | |||
T22304 | Desciclovir | BW A515U,6-Deoxyacyclovir,DCV | Antifection |
Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase. | |||
T9786 | Lu AF27139 | P2X Receptor | |
Lu AF27139 is an effective and selective antagonist of P2X7 receptor (IC50s of 12 and 2.4 nM for human and rat, Kis of 22, 54, and 13 nM for mouse, human, and rat, respectively). Lu AF27139 can be used in CNS diseases st... | |||
T7503 | Upadacitinib | ABT-494 | JAK |
Upadacitinib (ABT-494) (ABT-494) is a selective Janus kinase (JAK) 1 inhibitor, which is being studied for the treatment of several autoimmune disorders in the IC50 of 43 nM. | |||
T28167 | NGB 2904 | NGB2904 HCl,NGB-2904,NGB2904 | Others , Dopamine Receptor , 5-HT Receptor |
NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antag... | |||
T4628 | Seladelpar | MBX 8025 | PPAR |
Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia. | |||
T21593 | AAL-993 | VEGFR | |
AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on other tyrosine kinases. AAL993 also shows potent antiangiogeni... | |||
T60024 | CFT7455 | Cemsidomide | Ligand for E3 Ligase |
CFT7455 (Cemsidomide) is an anti-cancer agent showing high affinity to the cereblon E3 ligase with a Kd of 0.9 nM. CFT7455 is an orally active degrader of zinc finger transcription factors Ikaros (IKZF1), and Aiolos (IKZ... | |||
T21793 | CGP 35348 | GABA Receptor | |
CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice. | |||
T10826 | CK-666 | HIV Protease , Microtubule Associated | |
CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex. It binds to the Arp2/3 complex, stabilizes the inactive state of the complex, blocking the movement of the Arp2 and Arp3 subunits into the act... | |||
T0600 | 10,11-Dihydrocarbamazepine | Dihydrocarbamazepine | Others |
10,11-Dihydrocarbamazepine (Dihydrocarbamazepine) is used as pharmaceutical intermediates. | |||
T2578 | Didanosine | ddI,2',3'-Dideoxyinosine | HIV Protease , Reverse Transcriptase |
Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM). | |||
T9627 | PHD-1-IN-1 | HIF/HIF Prolyl-Hydroxylase | |
PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM). | |||
T38862 | Nandrolone acetate | 19-Nortestosterone 17β-acetate | Others |
Nandrolone acetate (19-Nortestosterone 17β-acetate) is a competitive inhibitor of isomerase with the Ki of 7 μM for Δ5-3-ketosteroid isomerase of Pseudomonas testosreroni. | |||
T0389 | Dabigatran etexilate | BIBR 1048 | Thrombin |
Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. | |||
T1448 | Dasatinib | BMS-354825 | Apoptosis , Bcr-Abl , Src , c-Kit , Autophagy |
Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive. Dasatinib has antitumor activity and is used in the treatment of leukemia and ly... | |||
T22675 | Co 102862 | V 102862 | Others , Sodium Channel |
Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies. | |||
T21976 | ONO-8130 | Prostaglandin Receptor | |
ONO-8130 is an orally available antagonist of EP1 receptor. | |||
T21696 | SC-57461A | Aminopeptidase | |
SC 57461A is a potent and specific leukotriene A4 hydrolase (LTA4H) inhibitor. | |||
T22436 | Takeda-6d | VEGFR | |
Takeda-6d, a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor, inhibits B-RAF and VEGFR2 with IC50 of 7.0nM and 2.2nM. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T11351 | Galanthamine N-Oxide | AChE | |
Galanthamine N-Oxide, an alkaloid extracted from Zephyranthes concolor bulbs, effectively inhibits acetylcholinesterase (AChE) from electric eel with an EC50 of 26.2 μM. It acts as a significant inhibitor of substrate ac... | |||
T3858 | Macranthoidin A | Others | |
Macranthoidin A has anti-inflammation activity. | |||
T4S1114 | Dryocrassin ABBA | Dryocrassin | Influenza Virus , Antibacterial |
Dryocrassin ABBA (Dryocrassin) is a flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities. | |||
T1560 | Prednisolone | Predonine,Hydroretrocortine,Metacortandralone | Glucocorticoid Receptor , Endogenous Metabolite |
Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. | |||
T5784 | Topotecan | NSC 609669,SKF 104864A | Topoisomerase , Autophagy |
Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases. | |||
T1611 | Isotretinoin | 13-cis-Retinoic acid | Retinoid Receptor , Endogenous Metabolite , Autophagy |
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall... | |||
T1326 | Gentamicin sulfate | SCH9724,Gentamycin sulfate,NSC-82261 | ribosome , DHFR , Antibacterial , Antibiotic |
Gentamicin sulfate (SCH9724) is a wide-spectrum, aminoglycoside antibiotic used to inhibit protein synthesis in sensitive organisms. | |||
T0974 | Novobiocin Sodium | Albamycinsodium,Cathomycin,Albamycin | Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy |
Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim... | |||
T5283 | NADH disodium salt | Disodium NADH,NADH, disodium salt hydrate | Others , Endogenous Metabolite |
NADH disodium salt (Disodium NADH) hydrate is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process, NADH disodium salt hydrate becomes oxid... | |||
TN6774 | Emodin 6-O-β-D-glucoside | Glucoemodin | Others |
Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside ... | |||
T6194 | Fidaxomicin | Tiacumicin B,OPT-80,Clostomicin B1,PAR-101 | Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic |
Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults. Fidaxomicin has minimal systemic absorption and has not been linked to serum enzyme el... | |||
T2719 | Succinic acid | Asuccin,Amber acid,1,2-Ethanedicarboxylic acid,Wormwood acid,Butanedioic acid,1,4-Butandioic Acid | Endogenous Metabolite |
Succinic acid (1,2-Ethanedicarboxylic acid) is a water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is al... | |||
T2881 | Crustecdysone | Commisterone,B-ecdysone,Commisterone,20-Hydroxyecdysone,Ecdysterone,B-ecdysone,Hydroxyecdysone | Others , Caspase , Endogenous Metabolite , Autophagy |
Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects. | |||
T3417 | Amentoflavone | Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin | Apoptosis , P450 , Phospholipase , Reactive Oxygen Species , Opioid Receptor , COX , Antibacterial , RSV , Antifungal |
Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhib... | |||
T2755 | Rhoifolin | Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside | Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy |
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves. | |||
T0646 | 5-Aminosalicylic Acid | Mesalazine,5-ASA,Mesalamine | NF-κB , Lipoxygenase , COX , Glutathione Peroxidase , Endogenous Metabolite , PAK , PPAR |
5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. | |||
T20191 | (-)-Camphoric acid | L-Camphoric acid,Camphoric acid, (-)- | GluR |
(-)-Camphoric acid (L-Camphoric acid) is a less active enantiomer of Camphoric acid which induces GluR expression. | |||
T4082 | Astragaloside | MMP , ERK , JNK | |
Astragaloside, one of the main active ingredients in Astragalus membranaceus. | |||
T19398 | L-Octanoylcarnitine | Others | |
L-Octanoylcarnitine is the physiologically active form of octanoylcarnitine. | |||
T3055 | Liensinine Perchlorate | Apoptosis , Others | |
Liensinine is the active constituent of plumula nelambinis with anti-hypertension. | |||
T3912 | Saikosaponin B1 | Others | |
Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro. | |||
T3758 | 2,6-Dimethoxybenzoic acid | Others , Endogenous Metabolite | |
2, 6-Dimethoxybenzoic acid is an active biochemical. | |||
T3760 | 2'-Hydroxy-5'-methoxyacetophenone | 5-Methoxy-2-hydroxyacetophenone | Others |
2'-Hydroxy-5'-methoxyacetophenone (5-Methoxy-2-hydroxyacetophenone) is an active biochemical. | |||
T8263 | 3,4'-Dihydroxyflavone | Influenza Virus | |
3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid. 3,4'-Dihydroxyflavone (3,4'-DHF) shows antiviral activity against Influenza A virus. | |||
T19554 | L-Aspartic aicd sodium | L-Aspartic acid sodium,Sodium L-aspartate | Others , Sodium Channel , Endogenous Metabolite |
L-Aspartic aicd sodium (Sodium L-aspartate) is an amino acid, a precursor active molecule for colon-specific active molecule delivery, that promotes Na+ efflux from rat forebrain membrane vesicles. | |||
T3742 | 3-Methylcatechol | 3-Methylpyrocatechol,2,3-Toluenediol,2,3-dihydroxytoluene | Others |
3-Methylcatechol (2,3-Toluenediol) is an active biochemical. | |||
T3764 | 1-Triacontanol | Myricyl alcohol,1-Triacontanol,Melissyl alcohol,Well-Bloom,Miraculan,Lithospermoside,triacontan-1-ol | Others |
1-Triacontanol (Melissyl alcohol) is an active biochemical | |||
T5556 | 5a-Pregnane-3,20-dione | Endogenous Metabolite | |
5a-Pregnane-3,20-dione is a biologically active 5-alpha-reduced metabolite of plasma progesterone | |||
T13669 | (E)-Cinnamamide | trans-Cinnamamide | Others |
(E)-Cinnamamide (trans-Cinnamamide) is the less active isomer of Cinnamamide which is an effective non-lethal chemical repellent suitable for reducing avian pest damage. | |||
TL0002 | Liquiritin apioside | Others | |
Liquiritin Apioside is one of the main active components in Suan-Zao-Ren decoction as a treatment for insomnia. | |||
T3820 | Iridin | Lridin | Others |
Iridin (Lridin) is major active ingredient of Iris dichotoma which could be used as the drug for pain, inflammation treatment | |||
T6S1652 | Benzoylpaeoniflorin | COX | |
1. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes. | |||
T36850 | Curvulin | Microtubule Associated | |
Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly. | |||
T3227 | Danshensu | Salvianic acid A,Dan shen suan A | Apoptosis , Nrf2 , Autophagy |
Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit. | |||
T2907 | Tanshinone I | Tanshinone A | Phospholipase |
Tanshinone I (Tanshinone A), an active principle isolated from the herbal medicine Salvia miltiorrhiza, displays cytotoxicity against tumor cells. | |||
TN1927 | Methyl Kakuol | 1-(6-methoxy-1,3-benzodioxol-5-yl)propan-1-one | TRP/TRPV Channel |
Methyl Kakuol is an agonist of TRPA1 with an EC50 of 0.27 µM and can be used in studies about acting as an active ingredient in MBST constituent Asiasari Radix. | |||
T0809 | Dicoumarol | Dicumarol | Dehydrogenase , NADPH , PDK |
Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol is a competitive inhibitor of vitamin K epoxidereductase; t... | |||
T6S1884 | Benzoylhypaconine | Benzoylhypacoitine | Others |
Benzoylhypaconine (Benzoylhypacoitine) might be the principal active components which affect mitochondrial growth by Fuzi and its processed products. | |||
T4911 | α-Arbutin | 4-hydroxyphenyl-D-lucopyranoside,alpha-Arbutoside,alpha-Arbutin | Tyrosinase |
α-Arbutin (4-hydroxyphenyl-D-lucopyranoside) is a synthetic and functional active ingredient for skin lightening. | |||
T4587 | Mirificin | BCP10902,Puerarin Apioside | Tyrosinase |
Mirificin (BCP10902) is an active ingredient in Tongmai formula (TMF) which is a well-known Chinese medicinal preparation. Anti-oxidant. | |||
T6S0630 | Hypaconitine | P450 , TNF | |
Hypaconitine, an active and highly toxic constituent derived from Aconitum species, has anti-inflammatory activity, is widely used to treat rheumatism. | |||
T1653 | Liothyronine | Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,Triiodothyronine,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine | Thyroid hormone receptor(THR) , Endogenous Metabolite |
Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity. | |||
T3745 | 3,4-Dimethoxyphenol | 4-Hydroxyveratrole,3,4-dimethoxyphel | Tyrosinase |
3,4-Dimethoxyphenol (4-Hydroxyveratrole) is an active biochemical. | |||
T21495 | Spinosyn A | Others | |
Spinosyn A is a polyketide-derived macrolide produced by Saccharopolyspora spinosa and is an active ingredient in several commercial insecticides. | |||
TMO2787 | Anthraquinone | dioxoanthracene,Anthradione,anthracenedione | Virus Protease |
Anthraquinone (Anthradione)s are the main active constituents in herbs often used to relieve constipation. | |||
T3S2197 | Polygalic acid | Senegenic acid | Others |
Polygalic acid (Senegenic acid), a triterpenoid saponin, is a major active ingredient in Polygala tenuifolia. Polygalic acid shows expectorant, emetic and stimulant effects. | |||
T2793 | Tetrahydropalmatine | DL-Tetrahydropalmatine,Rotundine | Apoptosis , Others , Dopamine Receptor |
Tetrahydropalmatine (DL-Tetrahydropalmatine) is an active component isolated from corydalis, suppressing amygdaloid release of dopamine to inhibit an epileptic attack in rats. | |||
T0788 | Spectinomycin dihydrochloride | Spectinomycin 2HCl,Actinospectacin | ribosome , Antibacterial , Antibiotic |
Spectinomycin dihydrochloride (Actinospectacin) is an antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea. | |||
TN1499 | Cimiracemoside C | Cimicifugoside M | AMPK |
Cimiracemoside C (Cimicifugoside M) is an active component of Cimicifuga racemosa. It activates AMPK and has the potential activity against diabetes. | |||
T2S1181 | Aloenin | Aloenin A,Aloearbonaside | Beta-Secretase , AChR |
1. Aloenin (Aloenin A) and aloe-emodin are active principles for inhibition of c-ADH and c-ALDH activities in vitro. | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPK-00539 | PLAU/uPA Protein (active form), Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro... | |||
TMPK-00274 | PLAU/uPA Protein (active form), Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro... | |||
TMPY-02047 | C-Reactive Protein Protein, Rat, Recombinant (His) | Rat | HEK293 |
C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reacti... | |||
TMPK-00114 | C-Reactive Protein /CRP Protein, Human, Recombinant (His) | Human | HEK293 |
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ... | |||
TMPY-03363 | C-Reactive Protein Protein, Human, Recombinant | Human | HEK293 |
C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reacti... | |||
TMPY-01581 | C-Reactive Protein Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reacti... | |||
TMPY-05336 | C-Reactive Protein Protein, Human, Recombinant, Biotinylated | Human | HEK293 |
C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reacti... | |||
TMPK-01333 | C-Reactive Protein /CRP Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ... | |||
TMPY-06937 | C-Reactive Protein Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reacti... | |||
TMPY-05249 | ITK Protein, Human, Recombinant (Actived By LCK, GST) | Human | Baculovirus-Insect Cells |
IL-2-inducible T cell kinase is a member of the protein kinase superfamily, Tyr protein kinase family, and TEC subfamily. It contains 1 Btk-type zinc finger, 1 PH domain, 1 protein kinase domain, 1 SH2 domain, and 1 SH3 ... | |||
TMPY-00382 | Thioredoxin/TRX Protein, Mouse, Recombinant | Mouse | E. coli |
Thioredoxin, also known as ATL-derived factor, Surface-associated sulphydryl protein, SASP and TXN, is a nucleus, cytoplasm and secreted protein that belongs to the thioredoxin family. Thioredoxins are proteins that act ... | |||
TMPY-01477 | MMP-2 Protein, Human, Recombinant | Human | HEK293 |
Matrix Metalloproteinase-2 (MMP-2) is an enzyme that degrades components of the extracellular matrix and thus plays a pivotal role in cell migration during physiological and pathological processes. MMP-2 expression is de... | |||
TMPY-00464 | M-CSF/CSF1 Protein, Mouse, Recombinant | Mouse | HEK293 |
Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim... | |||
TMPJ-00254 | TGF beta 3 Protein, Human/Mouse/Rat, Recombinant | Human,Mouse,Rat | Human Cells |
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes acti... | |||
TMPY-01288 | Osteopontin Protein, Human, Recombinant (His) | Human | HEK293 |
Osteopontin, also known as Secreted phosphoprotein 1, Bone sialoprotein 1, BSP-1, OPN, and SPP1, is a member of the osteopontin family and a SIBLING glycoprotein. Osteopontin has been classified as T-helper 1 cytokine an... | |||
TMPY-05717 | Integrin alpha V beta 8 Protein, Human, Recombinant (His) | Human | HEK293 |
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cyto... | |||
TMPY-06988 | Osteopontin Protein, Human, Recombinant (aa 17-166, His) | Human | HEK293 |
Osteopontin, also known as Secreted phosphoprotein 1, Bone sialoprotein 1, BSP-1, OPN, and SPP1, is a member of the osteopontin family and a SIBLING glycoprotein. Osteopontin has been classified as T-helper 1 cytokine an... | |||
TMPY-01896 | HGFR/c-Met Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR... | |||
TMPY-01008 | VEGFD Protein, Human, Recombinant (His) | Human | HEK293 |
Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active... | |||
TMPY-01735 | Carbonic Anhydrase 2 Protein, Human, Recombinant (His) | Human | E. coli |
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bi... | |||
TMPY-01296 | HGFR/c-Met Protein, Human, Recombinant (His) | Human | HEK293 |
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR... | |||
TMPY-00548 | HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR... | |||
TMPY-04384 | Src Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C... | |||
TMPY-01389 | HER3/ERBB3 Protein, Human, Recombinant (His) | Human | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-00246 | HER3/ERBB3 Protein, Rhesus, Recombinant | Rhesus | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-03024 | HER3/ERBB3 Protein, Rat, Recombinant (His) | Rat | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-00672 | Azurocidin/CAP37 Protein, Human, Recombinant (His) | Human | HEK293 |
Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil... | |||
TMPY-04956 | HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-02215 | Coagulation factor IX/F9 Protein, Human, Recombinant (His) | Human | HEK293 |
Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, on... | |||
TMPY-00399 | HER3/ERBB3 Protein, Human, Recombinant | Human | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-02477 | HER3/ERBB3 Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-02365 | HER3/ERBB3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin... | |||
TMPY-02846 | CLPS Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Colipase belongs to the colipase family. Structural studies of the complex and of colipase alone have revealed the functionality of its architecture. It is a small protein with five conserved disulphide bonds. Structural... | |||
TMPY-02585 | Acid sphingomyelinase/SMPD1 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Sphingomyelin phosphodiesterase 1 (SMPD1) , also known as ASM ( acid sphingomyelinase ), is a member of the acid sphingomyelinase family of enzymes. Three isoforms have been identified, isoform 1 is 631 amino acids (aa) ... | |||
TMPY-01672 | ICOS ligand Protein, Human, Recombinant (His) | Human | HEK293 |
Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmembrane glycoprotein with extracellular IgV and IgC domains an... | |||
TMPY-01111 | IL-18BP Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ... | |||
TMPY-05492 | IL-18BP Protein, Human, Recombinant (aa 1-192, hFc) | Human | HEK293 |
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ... | |||
TMPY-00846 | IL-18BP Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin-18-binding protein (IL-18BP) is a constitutively expressed and secreted protein. IL-18BP is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin ... | |||
TMPJ-00137 | APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His) | Human | Human Cells |
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to relea... | |||
TMPY-05641 | B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei... | |||
TMPY-02031 | B7-H3 Protein, Human, Recombinant (His) | Human | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei... | |||
TMPY-04064 | B7-H3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei... | |||
TMPY-04262 | B7-H3 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei... | |||
TMPY-00835 | IGFBP-3 Protein, Human, Recombinant (His) | Human | HEK293 |
The Insulin-like Growth Factor (IGF) signaling system plays a central role in cellular growth, differentiation, and proliferation. IGFBP3 is the most abundant IGF binding protein in human serum and is a growth inhibitory... | |||
TMPY-04774 | ALK-2/ACVR1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been... | |||
TMPY-00978 | Progranulin Protein, Human, Recombinant (His) | Human | HEK293 |
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, ... | |||
TMPY-01725 | Leptin Receptor Protein, Human, Recombinant (His) | Human | HEK293 |
Leptin Receptor or CD295 belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-spe... | |||
TMPY-03273 | IL-18 Protein, Mouse, Recombinant | Mouse | E. coli |
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g... | |||
TMPY-03290 | HGF Protein, Mouse, Recombinant | Mouse | HEK293 |
Hepatocyte growth factor, also known as HGF, contains 4 kringle domains, 1 PAN domain, and 1 peptidase S1 domain. It belongs to the peptidase S1 family, plasminogen subfamily. The hepatocyte growth factor is secreted by ... | |||
TMPY-00277 | IL-18 Protein, Human, Recombinant | Human | E. coli |
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g... | |||
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カタログ番号 | 製品名 | ||
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L2160 | Anti-Cancer Active Compound Library | 3250 compounds | |
A unique collection of 3250 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); | |||
L9850 | Orally Active Compound Library | 2484 compounds | |
A unique collection of 2484 of orally active compounds for high-throughput screening and high-content screening. | |||
L9900 | Inactive Ingredient Library | 184 compounds | |
L4010 | Bioactive Compounds Library Max | 22706 compounds | |
A collection of 22706 bioactive compounds for high-throughput screening, high-content screening, cell induction and target identification. | |||
L4150 | Featured Novel Bioactive Compound Library | 990 compounds | |
It is well-selected from Bioactive compound library Plus (D7800), from which 1-15 compounds with the highest scores (activity value, pharmacological properties, structure-diversity, etc.) were chosen. This library consis... | |||
L4000 | Bioactive Compound Library | 14590 compounds | |
A collection of 14590 small molecule compounds with validated activity for high throughput screening (HTS), high content screening (HCS), cell induction, and target identification; | |||
L7000 | Bioactive Lipid Compound Library | 385 compounds | |
A unique collection of 385 bioactive lipids related compounds for high throughput screening (HTS) and high content screening (HCS), including Agonists & Antagonists, Endocannabinoids, Farnesyl/geranylgeranyl derivates, ... | |||
L6810 | Traditional Chinese Medicine Monomer Library | 2771 compounds | |
A unique collection of 2771 compounds (TCM monomers) sourcing from traditional Chinese Medicines, is a powerful tool for drug discovery and research in mechanism; | |||
L1500 | GPCR Compound Library | 1940 compounds | |
A unique collection of 1940 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research; | |||
L6800 | Chinese Pharmacopoeia Natural Product Library | 2070 compounds | |
A unique collection of 2070 natural products included in Chinese Pharmacopoeia (CP), a powerful tool for drug development and pharmacological study; | |||
L1580 | GPCR Compound Library Plus | 338 compounds | |
Well-chosen 338 GPCR targeting compounds with unique structures; | |||
L2521 | Glycolysis Compound Library | 560 compounds | |
560 glycolysis-related active compounds for high-throughput and high-content screening. | |||
L6750 | PBCRBS Traditional Chinese Medicine Compound Library | 588 compounds | |
A unique collection of 588 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis. | |||
L7800 | High Solubility Fragment Library | 2731 compounds | |
Structurally diverse, medicinally active, and unique chemistry (strong IP potential); | |||
L6900 | Rare Natural Product Library | 180 compounds | |
A unique collection of 180 rare natural products, which can be used for high throughput screening (HTS) and high content screening (HCS); | |||
L6220 | Traditional Mongolian Medicine Compound Library | 960 compounds | |
A collection of 960 natural product molecules originated from Mongolian medicine, which can be used for high-throughput and high-content screening. | |||
L1720 | Nucleotide Compound Library | 337 compounds | |
A unique collection of 337 nucleoside and nucleotide analogues, can be used for research and development of anti-viral, anti-tumor, anti-fungal, and anti-depressive drugs; | |||
L6110 | Alkaloid Natural Product Library | 468 compounds | |
A unique collection of 468 natural alkaloids can be used for high throughput and high content screening; | |||
L2500 | Human Endogenous Metabolite Library | 508 compounds | |
A collection of 508 selected human endogenous metabolites for high throughput and high content screening. | |||
L8720 | Pyroptosis Compound Library | 1077 compounds | |
1077 types of active small molecules associated with pyroptosis for high-throughput and high-content screening. | |||
L6120 | Flavonoid Natural Product Library | 477 compounds | |
A unique collection of 477 flavonoids can be used for high throughput and high content screening; | |||
L5100 | Fluorochemical Library | 583 compounds | |
A unique collection of 583 fluorochemicals that can be used for high through-put screening (HTS) and high content screening (HCS); | |||
L6210 | Tibetan medicine Compound Library | 754 compounds | |
A collection of 754 natural product molecules originated from Tibetan medicine, which can be used for high-throughput and high-content screening. | |||
L6400 | Marine Natural Product Library | 148 compounds | |
A unique collection of 148 marine natural products for high throughput screening (HTS) and high content screening (HCS); | |||
L6820 | Tobacco Monomer Library | 750 compounds | |
L6740 | Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library | 386 compounds | |
A collection of 386 TCM monomers with anti-colorectal activity. An effective tool for drug development and pharmacological studies. |