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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T21059 | Ticagrelor metabolite M5 | Ticagrelor metabolite M5,,T437700,AR-C133913XX | P2Y Receptor |
Ticagrelor metabolite M5 (T437700) is a metabolite of Ticagrelor, the first reversible oral antagonist of P2Y12 receptor. Compared to Clopidogrel, Ticagrelor has faster and more consistent inhibition on ADP-receptors. Ti... | |||
T16045 | Methotrexate metabolite | DAMPA | Antifolate , Drug Metabolite |
Methotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherapeutic agent and immunosuppressant. | |||
T10738 | Abemaciclib metabolite M20 | CDK4/6-IN-4,LSN3106726 | CDK |
Abemaciclib metabolite M20 (CDK4/6-IN-4) is an active metabolite of Abemaciclib. Abemaciclib metabolite M20 is a selective CDK4/6 inhibitor and can be used for researches on the treatment of cancer. | |||
T10220 | Abemaciclib metabolite M2 | Abemaciclib Metabolites M2 | CDK |
Abemaciclib Metabolites M2 is a metabolite of abemaciclib, acts as a potent CDK4 and CDK6 inhibitor (IC50s: 1-3 nM) with anti-cancer activity. | |||
T10814 | Cinacalcet metabolite M4 | Rarechem AL BW 1078 | Calcium Channel |
Cinacalcet metabolite M4 (Rarechem AL BW 1078) is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor. | |||
T13133 | Tetrabenazine Metabolite | (-)-β-Dihydrotetrabenazine,(-)-β-HTBZ | Monoamine Transporter |
Tetrabenazine Metabolite ((-)-β-HTBZ), a vesicles monoamine transporter 2 (VMAT2) inhibitor, is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite has a high affinity for VMAT2 with a Ki of 13.4 nM. Tetraben... | |||
T12309 | Omeprazole metabolite Omeprazole sulfone | Omeprazole sulphone,Omeprazole sulfone | Others |
Omeprazole metabolite Omeprazole sulfone can inhibit proton pump. | |||
T5401 | GSK2983559 active metabolite | GSK2983559,RIPK2 inhibitor 1,RIPK2-IN-1 | RIP kinase |
GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor. | |||
T37181 | Avanafil metabolite M4 | Avanafil metabolite M4 | |
Avanafil metabolite M4 is a major active metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil . Avanafil is metabolized by the cytochrome P450 (CYP450) isoforms CYP3A4 and CYP2C to the major metabolites avanaf... | |||
T36661 | Iloperidone metabolite P95 | Iloperidone metabolite P95 | |
Iloperidone metabolite P95 is a metabolite of the atypical antipsychotic iloperidone . It binds to the serotonin (5-HT) receptor subtype 5-HT2A and α1-, α2B-, and α2C-adrenergic receptors with mean Ki values of 7.08, 21.... | |||
T36662 | Imidafenacin Metabolite M4 | Imidafenacin Metabolite M4 | |
Imidafenacin metabolite M4 is a metabolite of the muscarinic acetylcholine receptor antagonist imidafenacin.1It is formed from imidafenacin by the cytochrome P450 (CYP) isoform CYP3A4. 1.Kanayama, N., Kanari, C., Masuda,... | |||
T11445 | GNF179 (Metabolite) | GNF179 Metabolite | Others |
GNF179 Metabolite, the derivative of GNF179—an optimized 8,8-dimethyl IP analog—demonstrates significant potency (4.8 nM against the multidrug-resistant W2 strain) alongside in vitro metabolic stability and in vivo oral ... | |||
T12229 | Niraparib metabolite M1 | M1 metabolite of niraparib,Niraparib carboxylic acid metabolite M1 | Others |
Niraparib metabolite M1 is niraparib metabolite, niraparib is a novel poly(ADP-Ribose) polymerase (PARP) inhibitor. | |||
T23983 | Deutetrabenazine metabolite M4 | SD-1018,Deuterated monohydroxy tetrabenazine,D6-tetrabenazine metabolite M4 | |
Deutetrabenazine metabolite M4 is believed to be related to its effect as a reversible depletion of monoamines from nerve terminals. The major circulating metabolites of Deutetrabenazine, are reversible inhibitors of VM... | |||
T37638 | Tofacitinib metabolite-1 | ||
Tofacitinib metabolite-1, a derivative of Tofacitinib, which is a JAK inhibitor, is employed in studies focused on the pharmacokinetics and metabolism of tofacitinib[1][2]. | |||
T37180 | Avanafil metabolite M16 | ||
Avanafil metabolite M16 is a major inactive metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil . Avanafil is metabolized by the cytochrome P450 (CYP450) isoforms CYP3A4 and CYP2C to the major metabolites ava... | |||
T39345 | Lopinavir Metabolite M-1 | ||
Lopinavir Metabolite M-1, an active metabolite derived from Lopinavir, effectively inhibits the HIV protease enzyme with a Ki value of 0.7 pM. Additionally, in vitro studies have revealed notable antiviral properties ass... | |||
T68375 | KD026-metabolite | ||
KD026-metabolite, is a metabolite of KD-026. KD026, also known as SLx-4090, is a microsomal triglyceride transfer protein (MTTP) inhibitor potentially for the treatment of type 2 diabetes. | |||
T11893L | Lurasidone metabolite 14326 hydrochloride | Lurasidone metabolite 14326 hydrochloride (186204-33-1 free base) | Others |
Lurasidone metabolite 14326 hydrochloride, an active metabolite of the atypical antipsychotic Lurasidone, maintains its significant function in pharmacological efficacy. | |||
T20723 | LGE-899 | Sonidegib metabolite M48,LGE 899 | Drug Metabolite |
LGE-899 (Sonidegib metabolite M48) is a main metabolite of Sonidegib which is an inhibitor of the hedgehog pathway. The Tmax of LGE-899(60 h) is much longer than Sonidegib. | |||
T70178 | Sonidegib metabolite M25 | ||
Sonidegib metabolite M25 is a smoothened (SMO) antagonist. | |||
T12735 | Ritonavir metabolite | Desthiazolylmethyloxycarbonyl Ritonavir | Others |
Ritonavir metabolite is a Ritonavir metabolite, which is a inhibitor of HIV protease. | |||
T37645 | Dasatinib metabolite M6 | ||
Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative metabolite of Dasatinib, a potent and orally active inhibitor of both Bcr-Abl and Src family tyrosine kinases[1]. | |||
T2687 | Omeprazole sulfide | Omeprazole metabolite Omeprazole sulfide,Ufiprazole | Proton pump , Drug Metabolite |
Omeprazole sulfide (Ufiprazole), a metabolite of Omeprazole, functions as a proton pump inhibitor. | |||
T23950 | Dacomitinib metabolite M2 | Dacomitinib cysteine conjugate,UNII-SOA52D3NLL | |
Dacomitinib metabolite M2 is also known as Dacomitinib cysteine conjugate. Dacomitinib inhibits both the wild-type (WT) EGFR and EGFR T790M. | |||
T35815 | Vildagliptin carboxylic acid metabolite (trifluoroacetate salt) | ||
Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans. Vildagliptin carboxylic acid metabolite has an IC50 value of 477 μM for DPP-4 in hum... | |||
T11893 | Lurasidone metabolite 14326 | Others | |
Lurasidone metabolite 14326, an active metabolite of the atypical antipsychotic Lurasidone, functions effectively in the body. | |||
T71932 | MAM2201 N-pentanoic acid metabolite | ||
MAM2201 N-pentanoic acid metabolite is a potential phase 1 metabolite of MAM2201 -- a cannabinoid receptor agonist. | |||
T13525 | Abiraterone metabolite 1 | 3β-OH-5α-Abi | Others |
Abiraterone Metabolite 1, a 5β-reduced derivative of abiraterone, acts by inhibiting CYP17A1, thereby blocking androgen synthesis and extending survival in prostate cancer patients. | |||
T19406 | Lurasidone Metabolite 14283 D8 | Others | |
Lurasidone Metabolite 14283 D8 is the deuterium labeled Lurasidone Metabolite 14283. | |||
T19407 | Lurasidone Metabolite 14326 D8 | Others | |
Lurasidone Metabolite 14326 D8 is the deuterium labeled Lurasidone Metabolite 14326. | |||
T33659 | Nicardipine pyridine metabolite II | ||
Nicardipine pyridine metabolite II is a biaoctive chemical. | |||
T10358L | AR-13324 M1 metabolite | Others | |
AR-13324 M1 metabolite is a hydrolysis metabolite of AR-13324 mesylate. | |||
T12211 | Netupitant metabolite Monohydroxy Netupitant | Monohydroxy Netupitant | Others |
Monohydroxy Netupitant is a highly selective antagonist of NK1 receptor, and is Netupitant metabolite. | |||
T12689 | Ramelteon metabolite M-II | Others | |
Ramelteon metabolite M-II is the major Ramelteon metabolite(human melatonin receptors (MT1 or MT2) with IC50s of 208 pM, 1470 pM). Ramelteon is an agonist of selective melatonin. | |||
T13760 | Lurasidone Metabolite 14283 hydrochloride | Others | |
Lurasidone Metabolite 14283 hydrochloride is a major active metabolite of Lurasidone. | |||
T11641 | N-Desmethyl imatinib | Imatinib metabolite N-Desmethyl imatinib,Norimatinib | Bcr-Abl , PDGFR , c-Kit , Drug Metabolite |
N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR. | |||
T73909 | Abemaciclib metabolite M18 | LSN3106729 | Ligands for Target Protein for PROTAC |
Abemaciclib metabolite M18 (LSN3106729) is a potent cyclin-dependent kinase (CDK) inhibitor with antitumor properties. It has been incorporated alongside a cereblon (CRBN) ligand to develop a proteolysis-targeting chimer... | |||
T11637 | Iloperidone metabolite Hydroxy Iloperidone | P88,Hydroxy Iloperidone | Others |
Iloperidone metabolite Hydroxy Iloperidone is an atypical antipsychotic. It is a metabolite of Iloperidone. | |||
T12212 | Netupitant metabolite N-desmethyl Netupitant | N-desmethyl Netupitant | Others |
N-desmethyl Netupitant is a highly selective antagonist of NK1 receptor, and is Netupitant metabolite. | |||
T19175 | Acetaminophen metabolite 3-hydroxy-acetaminophen | 3-Hydroxyacetaminophen | Others |
3-hydroxy-acetaminophen is a metabolite of Acetaminophen. Acetaminophen is a pain medicine. | |||
T12213 | Netupitant metabolite Netupitant N-oxide | Netupitant N-oxide | Others |
Netupitant N-oxide is a highly selective antagonist of NK1 receptor, is Netupitant metabolite. | |||
T83676 | Tianeptine Metabolite MC5 sodium | ||
Tianeptine metabolite MC5, an active derivative of the atypical antidepressant tianeptine produced through β-oxidation, exhibits selective G protein activation in bioluminescence resonance energy transfer (BRET) assays. ... | |||
T10686 | Carvedilol metabolite 4-Hydroxyphenyl Carvedilol | 4-Hydroxyphenyl Carvedilol,4-Hydroxycarvedilol | Others |
4-Hydroxyphenyl Carvedilol is a metabolite of Carvedilol. Carvedilol is a beta-blocker/alpha-1 blocker. | |||
T11114 | Duloxetine metabolite Para-Naphthol Duloxetine | Para-Naphthol duloxetine | Others |
Para-Naphthol Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI),is a metabolite of Duloxetine. | |||
T32000 | GSK-1071306 | Pazopanib metabolite M27 | |
GSK-1071306 is a bio-active chemical. | |||
T19667 | R-138727 | Prasugrel active metabolite | |
R-138727 is a novel P2Y12 receptor inhibitor. | |||
T20465 | Ketopioglitazone | Keto pioglitazone,Pioglitazone metabolite M3 | |
Ketopioglitazone is an active metabolite of pioglitazone. | |||
T32828 | LNC-119 | Sonidegib metabolite M16,LNC119 | |
LNC-119 is an aminosteroid. | |||
T11987 | Mebeverine alcohol | Mebeverine metabolite Mebeverine alcohol | Others |
Mebeverine alcohol is a metabolite of Mebeverine. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T16338 | Norgestimate metabolite Norelgestromin | 17-Deacetyl norgestimate,17-Deacylnorgestimate | Drug Metabolite |
Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) is one of the active metabolites of norgestimate.It is a steroidal progestin used in contraceptive patches, where it is combined with the estrogen ethinyl es... | |||
Fr13756 | Isonicotinic acid | Endogenous Metabolite , Drug Metabolite | |
Isonicotinic acid is a metabolite of Isoniazid.Isonicotinic acid is a useful isomer of nicotinic acid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the biotransformation also to be catalyzed by cyt... | |||
T13539 | Allopurinol riboside | Others , Endogenous Metabolite , Parasite , Drug Metabolite | |
Allopurinol riboside is a metabolite of allopurinol and shows effective activities against parasites. | |||
T10815 | Cinnamoylglycine | Endogenous Metabolite | |
Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in humans. It is used as a potential urinary biomarker. | |||
T12287 | Octadecanedioic acid | Endogenous Metabolite | |
Octadecanedioic acid is an endogenous metabolite, is a long-chain dicarboxylic acid. | |||
TN1740 | Homoeriodictyol | 5-HT Receptor , transporter , Sodium Channel , Drug Metabolite | |
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotoni... | |||
T8153 | Glycohyodeoxycholic acid | Others , Endogenous Metabolite | |
glycohyodeoxycholic acid is a major metabolite of the secondary bile acid hyodeoxycholic acid in humans. | |||
T10021 | 1-Methylxanthine | Endogenous Metabolite | |
1-Methylxanthine is a caffeine derivative. 1-Methylxanthine is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells. | |||
T15720 | Lathosterol | Endogenous Metabolite | |
Lathosterol, a molecule akin to cholesterol, serves as a biomarker for the body's total cholesterol synthesis, as indicated by its serum concentration. | |||
T4799 | Indole | Others , Endogenous Metabolite | |
Indole has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. It can be produced by bacteria as a degradation product of the amino acid tryptophan. ... | |||
TN1490 | Chrysoeriol | ERK , p38 MAPK , Akt | |
Chrysoeriol has antioxidant, antiinflammatory, antitumor, antimicrobial, antiviral, and free radical scavenging activities, it also shows selective bronchodilator effect. | |||
T13719 | Hexadecanal | Palmitaldehyde | Endogenous Metabolite |
Hexadecanal (Palmitaldehyde) is a free fatty aldehyde present in animals. | |||
T20446 | Creosol | Endogenous Metabolite | |
Creosol is an agent of Antioxidant and Antibacterial. | |||
T8165 | Erythrodiol | Endogenous Metabolite , ABC | |
Erythrodiol, an olive oil component, promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. | |||
T0069 | Uracil | Others , Endogenous Metabolite | |
Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use in the body is to help carry out the synt... | |||
T5665 | Geraniol | Others , Endogenous Metabolite , Antifungal | |
geraniol provides a potent protective effect against cardiac dysfunction induced by diabetes. This ameliorative effect could be attributed to its suppression of oxidative stress. | |||
T8272 | Trierucin | Others , Endogenous Metabolite | |
Trierucin is a trierucic acid triglyceride isolated from the seed oil. | |||
T0647 | Tryptamine | Dehydrogenase , 5-HT Receptor , Endogenous Metabolite , TRP/TRPV Channel | |
Tryptamine is a monoamine alkaloid found in animals, plants, and fungi. It contains an indole ring structure and is structurally analogous to the tryptophan. It is found in trace amounts in the brains of mammals and is r... | |||
T0586 | Lactose | Others , Endogenous Metabolite | |
Lactose is a disaccharide derived from galactose and glucose that is found in milk. | |||
T19792 | 1,3,7-Trimethyluric acid | Others | |
1,3,7-Trimethyluric acid is a purine alkaloid that occurs as a minor metabolite of caffeine in humans. As an antioxidant, it has shown an ability to scavenge hydroxyl radicals as well as protective potential against lipi... | |||
T36790 | (Ethoxymethyl)benzene | Endogenous Metabolite | |
(Ethoxymethyl)benzene is an endogenous metabolite. | |||
T5352 | GLYCODEOXYCHOLIC ACID | Others , Endogenous Metabolite | |
Glycodeoxycholic Acid is a bile acid that induces severe pancreatitis in rats. It can induce the apoptosis of SMMC-7721 cells. | |||
T8086 | Decyl aldehyde | Others , Endogenous Metabolite | |
Decyl aldehyde is a ten-carbon aldehyde that is a substrate for bacterial luciferase. | |||
T8031 | Terephthalic acid | Others , Endogenous Metabolite | |
Terephthalic acid, an isomer of the three phthalic acids, serves as a precursor to the polyester PET, which is utilized in manufacturing plastic bottles and clothing. | |||
T7602 | Theaflavin | Influenza Virus , Endogenous Metabolite | |
Theaflavin is a polyphenolic flavonoid that has been found in black tea and has diverse biological activities, including antioxidant, anticancer, anti-inflammatory, and antiviral properties | |||
T8068 | O-Toluic acid | Others | |
o-Toluic acid, also 2-methylbenzoic acid, is an aromatic carboxylic acid. It is a human xenobiotic metabolite. | |||
T37508 | Meconin | Endogenous Metabolite | |
Meconin, a noscapine metabolite, is a urinary detection marker for illicit opiate misuse. This product is intended for use as a forensic standard. | |||
T4809 | Pyrimidine | Metadiazine | Others , Endogenous Metabolite |
Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and ... | |||
T37501 | Ethoxyacetic acid | Endogenous Metabolite | |
Ethoxyacetic acid is an endogenous metabolite of ethylene glycol monoethyl ether acetate. | |||
TN6833 | Octanal | Endogenous Metabolite , Antibacterial | |
octanal is a natural product with antioxidant and antimicrobial activities. | |||
T8049 | Pentadecanoic acid | Others , Endogenous Metabolite | |
Pentadecylic acid is a saturated fatty acid. | |||
T4794 | Glutaric acid | Endogenous Metabolite | |
Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan | |||
T2228 | Adipic acid | Others , Endogenous Metabolite | |
Adipic acid is a precursor for the production of nylon. | |||
T4776 | Glycerol | Glycerin | Endogenous Metabolite |
Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol... | |||
T12095 | Monomethyl fumarate | GPR , Drug Metabolite | |
Monomethyl fumarate is a potent agonist of GPR109A . | |||
T4761 | Pyridoxal hydrochloride | Others , Endogenous Metabolite | |
The 4-carboxyaldehyde form of vitamin B6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. | |||
T5985 | Glycolic acid | Tyrosinase , Endogenous Metabolite | |
Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation,and used in skincare products | |||
T5737 | Euphol | Others , Lipase , Endogenous Metabolite | |
Euphol, an alcohol tetracyclic triterpene, has a wide range of pharmacological properties and is considered to have anti-inflammatory action. | |||
TN6752 | Dimethyl sulfone | Endogenous Metabolite | |
Dimethyl sulfone exists in all living organisms, ranging from bacteria to humans. It derives from dietary sources, from intestinal bacterial metabolism and from human endogenous methanethiol metabolism. Dimethyl sulfone ... | |||
T37298 | Spinacine | Endogenous Metabolite | |
Spinacine has been isolated from spinach and the roots of Panax ginseng. This conformationally constrained amino acid is a structural element in certain biologically active compounds as glucagon antagonists and angiotens... | |||
T13581 | Biotin sulfone | Endogenous Metabolite | |
Biotin sulfone is isolated as a natural metabolite of biotin. | |||
TQ0284 | Hydroxyphenyllactic acid | Endogenous Metabolite , Antifungal | |
Hydroxyphenyllactic acid is an antifungal metabolite, fungi such as Lactobacillus sp. SK007. | |||
T19418 | Methionine sulfoxide | Endogenous Metabolite | |
Methionine sulfoxide, an oxidation product of methionine formed through interaction with reactive oxygen species, serves as a biomarker for oxidative stress in vivo. | |||
T5812 | Zinc Phytate | Others | |
Zinc Phytate, present in food, plays a crucial role in human nutrient absorption. | |||
T5565 | Undecanedioic acid | Others , Endogenous Metabolite | |
Undecanedioic acid has been found in parts of human aortas with advanced atherosclerotic lesions associated with intercellular matrix macromolecules and specifically with elastin. | |||
T5228 | Nicotinuric acid | Others , Endogenous Metabolite | |
Nicotinuric acid is an acyl glycine which is normally minor metabolites of fatty acids. Acyl glycines are produced through the action of glycine N-acyltransferase. | |||
T7331 | Ursocholic acid | Endogenous Metabolite | |
Ursocholic acid, a bile acid found predominantly in bile of mammals. | |||
T2724 | Caryophyllene oxide | Others , Endogenous Metabolite | |
Caryophyllene oxide is isolated from Aegle marmelos, with anti-inflammatory activity. | |||
T4883 | Creatine | Methylguanidoacetic acid | Endogenous Metabolite |
Creatine (Methylguanidoacetic acid) is an amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine. Creati... | |||
T5074 | Cholesteryl palmitate | Others , Endogenous Metabolite | |
Cholesteryl palmitic acid is a cholesteryl ester. A cholesteryl ester is an ester of cholesterol. Fatty acid esters of cholesterol constitute about two-thirds of the cholesterol in the plasma. Cholesterol is a sterol (a ... | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPH-00844 | HSD11B2 Protein, Human, Recombinant (His) | Human | Yeast |
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. | |||
TMPH-00843 | HSD11B1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one ... | |||
TMPY-03414 | ABHD10 Protein, Human, Recombinant (aa 53-306, His) | Human | Baculovirus-Insect Cells |
Mycophenolic acid (MPA), the active metabolite of the immunosuppressant mycophenolate mofetil (MMF), is primarily metabolized by glucuronidation to a phenolic glucuronide (MPAG) and an acyl glucuronide (AcMPAG). It is... | |||
TMPY-00320 | APOA1BP Protein, Human, Recombinant (His) | Human | HEK293 |
APOA1BP, now renamed NAXE, encodes an epimerase essential in the cellular metabolite repair for NADHX and NADPHX. The enzyme catalyzes the epimerization of NAD(P)HX, thereby avoiding the accumulation of toxic metabolites... | |||
TMPH-02615 | CBS Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cystei... | |||
TMPH-01597 | KYAT1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the thre... | |||
TMPH-02469 | PDK1 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus |
Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, a... | |||
TMPH-01598 | CCBL2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the thre... | |||
TMPY-02420 | HEMK2 Protein, Human, Recombinant (His) | Human | E. coli |
N6AMT1 (N-6 Adenine-Specific DNA Methyltransferase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes an N(6)-adenine-specific DNA methyltransferase. It belongs to t... | |||
TMPH-02877 | RIPK3 Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Serine/threonine-protein kinase that activates necroptosis and apoptosis, two parallel forms of cell death. Necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members, is triggere... | |||
TMPH-00839 | RIPK3 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Serine/threonine-protein kinase that activates necroptosis and apoptosis, two parallel forms of cell death. Necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members, is triggere... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L2500 | Human Endogenous Metabolite Library | 499 compounds | |
A collection of 499 selected human endogenous metabolites for high throughput and high content screening. | |||
L5800 | Drug Metabolite/Impurity Library | 197 compounds | |
A unique collection of 197 drug isomers/metabolites for high throughput screening (HTS) and high content screening (HCS); | |||
L2530 | Mouse Metabolite Compound Library | 218 compounds | |
A unique collection of 218 mouse metabolites, which can be used for HTS and HCS; | |||
L2540 | Gut Microbial Metabolite Library | 607 compounds | |
A unique collection of 607 gut microbial metabolites which can be used for HTS and HCS; | |||
L6001 | Mini Fungal Metabolite Natural Product Screening Library | Inquiry | |
L2570 | Human Metabolite Library | 4454 compounds | |
A unique collection of 4454 human metabolites for high-throughput, high-content screening. | |||
L2501 | Human Endogenous Metabolite Compound Library Plus | 1283 compounds | |
L5510 | Drug-induced Liver Injury (DILI) Compound Library | 1001 compounds | |
A unique collection of 1001 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening; | |||
L2560 | Metabolism Compound Library | 2320 compounds | |