Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM). Facinicline hydrochloride improves cognition and sensorimotor gating in rodents.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 22,500 | |||
5 mg | 在庫あり | ¥ 57,000 | |||
10 mg | 在庫あり | ¥ 95,000 | |||
25 mg | 在庫あり | ¥ 159,000 | |||
50 mg | 在庫あり | ¥ 226,000 | |||
100 mg | 在庫あり | ¥ 305,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 62,500 |
説明 | Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM). Facinicline hydrochloride improves cognition and sensorimotor gating in rodents. |
ターゲット&IC50 | α7 nAChR:6 nM (Ki), 5-HT3 receptor:1.2 nM (Ki) |
別名 | RG3487 |
分子量 | 306.79 |
分子式 | C15H19ClN4O |
CAS No. | 677305-02-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 100 mg/mL (325.96 mM)
DMSO: 125 mg/mL (407.44 mM)
You can also refer to dose conversion for different animals. 詳細
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Facinicline hydrochloride 677305-02-1 GPCR/G Protein Neuroscience AChR 5-HT Receptor Inhibitor nAChR serotonin 3 receptor Facinicline Hydrochloride RG3487 Nicotinic acetylcholine receptors Serotonin Receptor RG-3487 inhibit recognition 5-hydroxytryptamine Receptor RG 3487 Facinicline receptor memory nicotinic inhibitor