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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T7149 | S29434 | NADPH , Autophagy | |
S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM). | |||
T16411 | Otenzepad | AF-DX 116 | AChR |
Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung. | |||
T23256 | RS-25344 hydrochloride | PDE | |
RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor | |||
T8778 | TTK21 | Epigenetic Reader Domain | |
TTK21 is an activator of CBP/p300 histone acetyltransferase activity. | |||
T2301 | SB 202190 | FHPI,SB202190 | Apoptosis , p38 MAPK , Autophagy |
SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably. SB 202190 has antitumor activity and also induces the differentiation of human embryonic stem cells i... | |||
T14042 | 4-P-PDOT | 4-phenyl-2- propionamidotetralin | Melatonin Receptor , MT Receptor |
4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist. | |||
T28531 | Facinicline hydrochloride | RG3487 | 5-HT Receptor , AChR |
Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM). Facinicline hydrochloride improves cognition and sensorimot... | |||
T8702 | SKF-83566 | Dopamine Receptor , 5-HT Receptor , AChR | |
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 nM | |||
T8720 | PRX-07034 hydrochloride | PRX-07034 | 5-HT Receptor |
PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents. PRX-07034 hydrochloride is both a poten... | |||
T2264 | AM281 | Cannabinoid Receptor | |
AM 281, a cannabinoid antagonist, reduces neurologic dysfunction and mortality rate after cecal ligation and puncture in rats. | |||
T7823 | IDRA-21 | GluR | |
IDRA-21 is a positive AMPA receptor modulator. | |||
T29856 | Aleplasinin | PAZ 417,PAZ417,PAZ-417 | PAI-1 |
Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic system. Aleplasinin can be used in Alzheimer's disease studies... | |||
T23146 | PHA 568487 free base | PHA 568487 | AChR |
The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated lia... | |||
T1418 | Bucladesine sodium | dbcAMP,Dibutyryl-cAMP sodium salt,Dibutyryl-cAMP,DC2797,Sodium dibutyryl cAMP,Bucladesine,Bucladesine sodium salt | PKA , PDE |
Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties. Bucladesine sodium is also a cAMP-dependent protein kinase (PKA) activator and a phosphodiester (PDE) inhibitor. Bucladesine sodium has anti-in... | |||
T1406 | Amantadine hydrochloride | 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride | Dopamine Receptor , Influenza Virus |
Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease. | |||
T34435 | RU 47213 | RU-47213,Itameline,RU47213 | Others |
RU 47213 can be used to inhibit scopolamine-induced working memory impairment in rats. | |||
T5474 | D159687 | D 159687 | PDE |
D159687 is a selective PDE4D inhibitor,had a procognitive profile as it improved memory in the novel object recognition test but had no antidepressant or anxiolytic benefit. | |||
T21715 | BRD6688 | HDAC | |
BRD6688 is a selective HDAC2 inhibitor that acts by enhancing the learning and memory processes | |||
T5500 | DORA-22 | OX Receptor | |
DORA-22 is a dual orexin receptor antagonist, improves mild stress-induced insomnia with minimal effect on memory | |||
T7114 | GALANTHAMINONE | (-)-Narwedine,Narwedin | AChE |
Galanthaminone ((-)-Narwedine) is a cholinesterase (AChE) inhibitor, is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments. | |||
T26174 | SAK3 | SAK 3,SAK-3 | Calcium Channel , AChR |
SAK3 is a novel modulator of nAChR activity that enhances T-type voltage-gated Ca2+ channel (T-VGCC) activity, and has potentiating effects on both Cav3.1 and Cav3.3 T-type Ca2+ channel currents.SAK3 is neuroprotective a... | |||
T16783 | Rolziracetam | CI-911 | Others |
Rolziracetam (CI-911) is a nootropic drug of the racetam family. It can improve short-term memory in rats and monkeys. | |||
T23286 | S 24795 | Catestatin acetate(142211-96-9 free base),LNAChR | AChR |
S 24795 (Catestatin acetate(142211-96-9 free base)) is an α7 nAChR partial agonist. S 24795 improves mnemonic function in aged mice and can be used in studies about aging-related memory disturbances. | |||
T1401 | Meclofenoxate hydrochloride | Meclofenoxate (Centrophenoxine) HCl,Lucidril,Cerutil,Meclofenoxate HCl | Lipoxygenase , COX , AChR , iGluR |
Meclofenoxate hydrochloride (Lucidril) is an ester of DIMETHYLAMINOETHANOL and para-chlorophenoxyacetic acid. It has been shown to improve memory and general cognition, and mentally stimulating effect. | |||
T23331 | SC 51089 | SC 51089 free base | Prostaglandin Receptor |
SC 51089 is a selective prostaglandin receptor PGE2 antagonist with selectivity for prostaglandin receptor subtypes and antinociceptive activity that improves motor deficits and rescues memory decline in the Huntington's... | |||
T9379 | L-Threonic acid magnesium salt | Others | |
L-Threonic acid magnesium salt (L-TAMS) increases synapse density and memory ability in both aged rats and late stage Alzheimer’s disease (AD) model mice. | |||
T11244 | Etimizol | Ethymisol,Ethimizole,Ethymisole | Others |
Etimizol (Ethimizole) was shown to relieve amnesia effectively in the origin of which there is the hypoxic component (hypobaric hypoxia, actinomycin D, mechanical injury of the brain). The positive effect of Etimizol on ... | |||
T61278 | Aminopeptidase-IN-1 | Aminopeptidase | |
Aminopeptidase-IN-1 is a potent inhibitor of insulin-regulated aminopeptidase (IRAP) (Ki: 7.7 μM).Aminopeptidase-IN-1 can be used in studies of cognitive and memory disorders. | |||
T14507 | Bay 60-7550 | BAY 607550 | PDE |
Bay 60-7550 is a selective and potent PDE2 inhibitor (Ki: 3.8 nM) that exerts positive inotropic effects on rat heart by increasing PKA-mediated phosphorylation and can be used to ameliorate cognitive impairments and mem... | |||
T24184 | Itasetron | DAU6215CL,UNII-00S0D0OEKR,U-98079A,U 98079A,DAU 6215CL | 5-HT Receptor |
Itasetron (U 98079A) is a 5-hydroxytryptamine 3-receptor antagonist used to prevent age-related memory deficits in rats.Itasetron's antiemetic activity in animal models of cancer chemotherapy and radiation therapy may be... | |||
T30579 | BRD4097 | HDAC | |
BRD4097, a negative control in the HDAC1/2/3/8 assay, is a selective histone deacetylase (HDAC3) inhibitor that can be used to protect b-cells and improve insulin resistance, help promote cognitive function and enhance l... | |||
T8515 | Osoresnontrine | BI-409306 | PDE |
Osoresnontrine is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be used in the research of memory. | |||
T16034 | Meclinertant | SR 48692 | Others |
Meclinertant is an effective, selective, nonpeptide, and orally active neurotensin receptor 1 (NTS1) antagonist. Meclinertant competitively antagonizes neurotensin-induced intracellular Ca2+ mobilization (pA2 : 8.13), in... | |||
T25450L | GGTI 2147 FA | GGTI2147 FA,GGTI-2147 FA,GGTI 2147 FA(191102-87-1 Free base) | Others |
GGTI 2147 FA, a selective GGT inhibitor, abolishes bicuculline-induced increase in dendritic spine density in hippocampal experiments and may reduce learning and memory abilities in mice. | |||
T21556 | Hydroxytacrine maleate | Velnacrine maleate,HP 029 maleate | AChE |
Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase (cholinesterase) inhibitor that enhances memory in rodents and may be used in the study of Alzheimer's dementia of the Alzheimer type (SDAT). | |||
T50047 | 1-(3,4-dihydroxyphenyl)-2-(dimethylamino)ethan-1-one hydrochloride | Others | |
1-(3,4-dihydroxyphenyl)-2-(dimethylamino)ethan-1-one hydrochloride is a cholinergic agent that inhibits choline metabolism, which leads to increased levels of acetylcholine in the brain, which in turn enhances cognitive ... | |||
T50055 | Milacemide | MAO | |
Milacemide is a glycine prodrug and MAO-B inhibitor. Milacemide has been studied for its effects on human memory and as a potential treatment for the symptoms of Alzheimer's disease. | |||
T77678 | TZ3O | AChR | |
TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment and cognitive decay in Scopolamine-induced Alzheimer's type model in rats, and can be used in the study of Alzheimer's ... | |||
TP1981L | Neuropeptide S (Mouse) acetate | Neuropeptide Y Receptor | |
Neuropeptide S (Mouse) acetate is a bioactive peptide. Neuropeptide S (Mouse) acetate, as a neurotransmitter/neuromodulator of 20 amino acids, can be used for the research of arousal, anxiety, locomotion, feeding behavio... | |||
T60739L | Y13g dihydrochloride | Y13g 2HCl(T60739 Free base) | IL Receptor , AChE |
Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are related). Y13g dihydrochloride reverses STZ-induced memory defi... | |||
T77170 | Siplizumab | MEDI-507 | Others |
Siplizumab (MEDI-507) is a humanized IgG1 monoclonal antibody targeting CD2. Siplizumab selectively depletes effector memory T cells and promotes relative expansion of alloreactive regulatory T cells in vitro. Siplizumab... | |||
T16816 | S 18986 | GluR | |
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties in rodents. It induces the release of noradrenaline and acetylcholine... | |||
T34081 | Piromelatine | NEU-P-11,NEU-P 11,NEU-P11 | P2X Receptor , 5-HT Receptor , MT Receptor , Sodium Channel , TRP/TRPV Channel |
Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with inhibitory effects on P2X3, TRPV1, and Nav1.7 channels, and can be ... | |||
TP1570 | Cortistatin-14 | Somatostatin | |
Cortistatin-14, a neuropeptide structurally similar to growth inhibitor-14, has anticonvulsant and neuroprotective effects and impairs recognition memory consolidation in mice through activation of sst(2), growth hormone... | |||
T38192 | Unifiram | Others | |
Unifiram is a nootropic agent.1It increases acetylcholine (ACh) release in the rat cerebral cortexin vivoand induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the ra... | |||
T19337 | GBR 12783 dihydrochloride | GBR12783 2HCl | Others |
GBR 12783 dihydrochloride (GBR12783 2HCl) is a specific, potent and selective dopamine uptake inhibitor. GBR 12783 dihydrochloride inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 ... | |||
T67955 | Ensaculin | Anseculin | |
Ensaculin (Anseculin), a novel benzopyrone partially substituted with piperazine, showed memory-enhancing effects in passive and conditioned avoidance paradigms in normal and artificially amnesic rodents. It showed neuro... | |||
T22243 | Anserine | L-Anserine | Endogenous Metabolite |
Anserine (L-Anserine) is a dipeptide containing β-alanine and histidine, which can be found in the skeletal muscle and brain of mammals and birds. Anserine is not cleaved by serum carnosinase and act as biochemical buffe... | |||
T21792 | CGP 3466B maleate | Omigapil (Maleate),Omigapil maleate | Apoptosis |
CGP 3466B maleate (Omigapil maleate) is an orally bioavailable GAPDH nitrosylation inhibitor. Omigapil maleate abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. Omigapil male... | |||
T62899 | Tau-aggregation and neuroinflammation-IN-1 | Microtubule Associated , NO Synthase | |
Tau-aggregation and neuroinflammation-IN-1 is a potent inhibitor of tau protein aggregates, showing significant inhibitory activity against AcPHF6 and full-length tau protein aggregates. Tau-aggregation and neuroinflamma... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T2718 | Palmatine chloride | Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase | |
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties. | |||
T2950 | Schisandrin | Wuweizi alcohol-A,Wuweizichun-A,Schizandrol-A,Schizandrol | Autophagy |
Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects. | |||
T5S0802 | Palmatine | Berbericinine,Burasaine | Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase |
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,... | |||
T0469 | Octopamine hydrochloride | (±)-p-Octopamine hydrochlorid,(+,-)-Octopamine HCl | Dopamine Receptor , Endogenous Metabolite , Adrenergic Receptor |
Octopamine hydrochloride ((±)-p-Octopamine hydrochlorid) is a biogenic monoamine structurally associated with noradrenaline. It can serve as a neurohormone, a neurotransmitter, and a neuromodulator in invertebrates. | |||
T4110 | Perivine | Perivin | Others |
Perivine (Perivin) may resolve the instability of the retinoblastoma-associated proteins (RbAp48) complex and thus be used in Alzheimer's disease therapy. Perivine, vobasine, coronaridine and dichomine show hypotensive a... | |||
T7060 | Amantadine | 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine | Others |
Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. | |||
T3344 | Ciwujianoside B | yemuoside YM,acanthopanax senticosides B,Ciwujianoside-B | BCL , Others |
Ciwujianoside B (acanthopanax senticosides B) is the main component of Acanthopanax, can relieve fatigue, enhance memory, and improve human cognition. | |||
T0769 | Aceglutamide | N2-Acetylglutamine,α-N-Acetyl-L-glutamine | Amino Acids and Derivatives , Endogenous Metabolite , Autophagy |
Aceglutamide (N2-Acetylglutamine) is an acetyl derivative of the amino acid L-glutamine, used to improve memory. | |||
TN2230 | Soyasaponin Ba | Others | |
Soyasaponin Ba may represent viable candidates for effective vaccine adjuvants due to their higher and lower or non-haemolytic effects.Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without ... | |||
T2883 | Syringic acid | 3,5-dimethyl ether Gallic Acid,SYRA,3,5-dimethoxy-4-hydroxy Benzoic Acid,NSC 2129 | Others , Endogenous Metabolite , Antibacterial |
Syringic acid (3,5-dimethoxy-4-hydroxy Benzoic Acid) (SYRA) is a potential antioxidant used in traditional Chinese medicine and is an emerging nutraceutical. It has potential anti-angiogenic, anti-glycating, anti-hypergl... | |||
T3S0488 | Syringaresinol diglucoside | Syringaresinol-di-O-glucoside | Others |
Syringaresinol diglucoside (Syringaresinol-di-O-glucoside) protects the animals from the stress-induced decreases in sex behaviours and in rectal temperature, the stress-induced failure of retrieval of memory, and the st... | |||
T4956 | Tetrahydroxystilbene-2-O-β-D-glucoside | tetrahydroxyl diphenylethylene-2-o-gluco,EH-201 | Others |
Tetrahydroxystilbene-2-O-β-D-glucoside (EH-201) is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-β-D-glucoside induces expression of erythropoietin, PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astroc... | |||
T6S1294 | Nicotiflorin | Nictoflorin,Kaempferol-3-O-Rutinoside,Nicotifloroside | Others |
1. Nicotiflorin (Kaempferol-3-O-Rutinoside) has potential therapeutic effects on cerebral ischemic illness. 2. Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and oxidative s... | |||
T3911 | Pulchinenoside A | Anemoside A3 | Others |
Pulchinenoside A (Anemoside A3) is an attractive candidate for further development as a cognitive enhancer capable of alleviating memory dysfunctions associated with aging and neurodegenerative diseases. | |||
TN1236 | 3',4',7-Trihydroxyisoflavone | MAPK , JNK | |
3',4',7-Trihydroxyisoflavone is a soy isoflavone soy glycoside derivative and Cot (Tpl2/MAP3K8) and MKK4 inhibitor with anticancer, antiangiogenic and free radical scavenging properties.3',4',7-Trihydroxyisoflavone enhan... | |||
T5702 | Tenuifoliside B | Dehydrogenase | |
Tenuifoliside B is a natural product from the roots of Polygala tenuifolia.And is a target lactate dehydrogenase inhibitor. Tenuifoliside B has cognitive improving and cerebral protective effects. it can inhibit potassi... | |||
T4S1999 | Valepotriate | Valtrate | Apoptosis , HIV Protease |
Valepotriate (Valtrate) fraction can have sedative effects and affect behavioral parameters related to recognition memory. Valepotriates, a new class of cytotoxic and antitumor agents, they are very potent cytotoxic agen... | |||
T14305 | Apicidin | OSI 2040 | Apoptosis , HDAC , Autophagy |
Apicidin (OSI 2040) is a histone deacetylase (HDAC) inhibitor with antiparasitic activity and antiproliferative activity.Apicidin attenuates memory deficits, inhibits cell growth and proliferation, and induces apoptosis ... | |||
T1208 | Citicoline sodium | Citicoline sodium salt,CDP-choline | Apoptosis , Others , Endogenous Metabolite |
Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demons... | |||
T6S2227 | Spinosin | Flavoayamenin | Others |
1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammato... | |||
TN3472 | Axillaridine A | Others | |
Axillaridine A is a new cholinesterase inhibitors, it may act as potential leads in the discovery of clinically useful inhibitors for nervous-system disorders, particularly by reducing memory deficiency in Alzheimer's di... | |||
T81072 | Suffruticosol A | ||
Suffruticosol A, a neuroprotective compound isolated from the seeds of P. lactiflora [1], mitigates scopolamine-induced neurodegenerative cellular damage and improves hippocampal cholinergic function. Additionally, it pa... | |||
T79963 | Feralolide | ||
Feralolide, a dihydroisocoumarin from the methanolic extract of aloe vera resin, functions as a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with IC50 values of 55 μg/mL and 52 μg/mL, ... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPJ-00038 | IL-7 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 a... | |||
TMPJ-01172 | IL-17 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid seque... | |||
TMPJ-01461 | IL-15RA & IL-15 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R f... | |||
TMPJ-01462 | IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc) | Human | HEK293 Cells |
IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R f... | |||
TMPJ-01441 | OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expr... | |||
TMPH-01770 | Neurotrypsin Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. Neurotrypsin Protein, Human, Recombinant (His & SUMO) is expressed in... | |||
TMPH-01765 | Neuropeptide B Protein, Human, Recombinant | Human | E. coli |
May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway. Neuropeptide B Protein, Human, Recombinant is expressed in E. coli expression system. The predicted ... | |||
TMPH-01764 | Neuropeptide B Protein, Human, Recombinant (GST) | Human | E. coli |
May be involved in the regulation of feeding, neuroendocrine system, memory, learning and in the afferent pain pathway. Neuropeptide B Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GS... | |||
TMPJ-00629 | TIGIT Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT contains an immunoglobulin variable domain, a transmembrane... | |||
TMPJ-00694 | BRD4 Protein, Human, Recombinant (His & Flag) | Human | E. coli |
Bromodomain-containing protein 4 (BRD4) is a member of the BET class chromatin reader proteins that bind acetylated histones and play a key role in transcriptional regulation and transmission of epigenetic memory. Remain... | |||
TMPK-01416 | HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 Cells |
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 we... | |||
TMPK-00160 | IL-15RA Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelia... | |||
TMPK-00159 | IL-15RA Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelia... | |||
TMPK-01412 | HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 Cells |
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 we... | |||
TMPK-00237 | 2B4/CD244 Protein, Human, Recombinant (aa 22-221, His & Avi), Biotinylated | Human | HEK293 Cells |
2B4 (CD244) is expressed by memory-phenotype CD8() T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports ha... | |||
TMPK-00128 | CD7 Protein, Human, Recombinant (His & Avi), PE-Labeled | Human | HEK293 Cells |
CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily.CD7 is expressed on T cells, NK cells , myeloid progenitor cells, and CD19 B pro... | |||
TMPH-02013 | PTPRZ1 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligo... | |||
TMPK-00100 | CD7 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated | Mouse | HEK293 Cells |
CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily.CD7 is expressed on T cells, NK cells , myeloid progenitor cells, and CD19 B pro... | |||
TMPY-02442 | ELK1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
E twenty-six (ETS)-like transcription factor 1, also known as Elk1 or Member of ETS oncogene family (ELK1), is a member of the ETS oncogene superfamily which is characterized by a common protein domain that regulates DNA... | |||
TMPJ-01349 | SEMA4B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domai... | |||
TMPK-00129 | CD7 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily.CD7 is expressed on T cells, NK cells , myeloid progenitor cells, and CD19 B pro... | |||
TMPH-01065 | CCR4 Protein-VLP, Human, Recombinant (His) | Human | HEK293 Cells |
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger... | |||
TMPH-01064 | CCR4 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger... | |||
TMPY-03779 | CCL27 Protein, Human, Recombinant (His) | Human | E. coli |
CCL27, also known as CTACK, is a small cytokine belonging to the CC chemokine family. Members of this family are proteins characterized by two adjacent cysteines. CCL27 is chemotactic for skin-associated memory T lymphoc... | |||
TMPJ-01348 | SEMA4B Protein, Human, Recombinant (hFc & His) | Human | HEK293 Cells |
Semaphorin-4B is a single-pass type I membrane protein. SEMA4B is a member of the semaphorin family. The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B ... | |||
TMPH-00779 | IL-23 P19/IL23A Protein, Guinea Pig, Recombinant (His & Myc) | Guinea pig | E. coli |
Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 b... | |||
TMPJ-01243 | DEFB4 Protein, Human, Recombinant | Human | E. coli |
Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1,... | |||
TMPJ-00046 | IL-17F Protein, Human, Recombinant | Human | E. coli |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally relate... | |||
TMPY-06864 | GLP1R Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. GLP1R plays a critical role in mediating the biological actions of GLP1 in mammals and fish. The neuronal GLP1Rs mediate body weight and anorectic effects of li... | |||
TMPJ-00007 | NPY Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Pro-Neuropeptide Y (NPY) is a member of the NPY family. NPY is a secreted protein and is one of the most abundant peptides in the nervous system. It also can be found in some chromaffin cells of the adrenal medulla. NPY ... | |||
TMPY-02421 | PARP3 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Poly(ADP-ribose) polymerase 3 (PARP3) is an important member of the PARP family and shares high structural similarities with both PARP1 and PARP2. Poly(ADP-ribose) polymerase 3 (PARP3), a critical player in cellular resp... | |||
TMPJ-00009 | CCL2 Protein, Human, Recombinant | Human | E. coli |
The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine that belongs to the CC chemokine family responsible for mono... | |||
TMPY-04318 | GRIK2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar... | |||
TMPJ-00351 | IL-23R Protein, Human, Recombinant (aa 24-353, hFc) | Human | HEK293 Cells |
Interleukin 23 receptor (IL23R) is a type I cytokine receptor for IL23. IL23 receptor complex is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several cytokines, and a subunit that is unique to IL-... | |||
TMPY-04373 | CAMKII alpha/CAMK2A Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Ca2+/calmodulin-dependent protein kinase2A (CAMK2A) belongs to the serine/threonine protein kinase family and, together with other 28 different isoforms, belongs to the Ca2+/ calmodulin-dependent protein kinase subfamily... | |||
TMPJ-00216 | IL-12B Protein, Human, Recombinant | Human | HEK293 Cells |
Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, a... | |||
TMPJ-01444 | IL-17A Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it ... | |||
TMPJ-01219 | IL-23R Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Interleukin 23 receptor (IL23R), a heterodimer of the IL12 receptor β1 (IL12Rβ1) and IL12Rβ2, is a type I cytokine receptor for IL23. IL23R is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several ... | |||
TMPJ-00614 | CD47 Protein, Rhesus macaque, Recombinant (His & Flag) | Rhesus | HEK293 Cells |
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral membrane protein that consists of a extracellular domain (ECD)... | |||
TMPY-02977 | PDE1C Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds ... | |||
TMPJ-01337 | IL-21R Protein, Mouse, Recombinant (aa 20-236, His) | Mouse | HEK293 Cells |
Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. IL-21R is expressed mainly on B cells, NK cells, and activated T cells, but is also f... | |||
TMPJ-00782 | Amyloid Precursor Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and... | |||
TMPJ-00029 | CALM1 Protein, Human, Recombinant | Human | E. coli |
Calmodulin (CaM) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required f... | |||
TMPY-01992 | Kallikrein 8/KLK8 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Kallikrein-8, also known as Neuropsin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein, and KLK8 is a secreted protein that belongs to the peptidase S1 family and Ka... | |||
TMPJ-00226 | SLAMF1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Signaling lymphocyte activation molecule (SLAM), is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells, but also on the surface of activated B cells, dendritic cells, an... | |||
TMPY-01692 | NETO1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Neuropilin tolloid-like 1 (NETO1), a complement C1r/C1s, Uegf, Bmp1 (CUB) domain-containing transmembrane protein, is a novel component of the NMDAR complex critical for maintaining the abundance of NR2A-containing NMDAR... | |||
TMPJ-00060 | IL-25/IL17E Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins are secreted and are structurally related by sharing a con... | |||
TMPH-02317 | YTHDF1 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and regulates their stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stabi... | |||
TMPH-01282 | ELAVL4 Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in th... |
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