Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Filibuvir (PF-00868554) is a selective and noncovalent inhibitor of HCV NS5B RNA-dependent RNA polymerase. Filibuvir inhibits genotype 1a and 1b replicons with EC50s of 59 nM.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 15,000 | |||
5 mg | 在庫あり | ¥ 45,500 | |||
10 mg | 在庫あり | ¥ 67,500 | |||
25 mg | 在庫あり | お問い合わせ | |||
50 mg | 在庫あり | お問い合わせ |
説明 | Filibuvir (PF-00868554) is a selective and noncovalent inhibitor of HCV NS5B RNA-dependent RNA polymerase. Filibuvir inhibits genotype 1a and 1b replicons with EC50s of 59 nM. |
In vitro | In Huh7.5 cells, Filibuvir (0.01-10000 nM; 48 h) dose-dependently inhibits the WT 1b replicon with EC50s of ∼70 nM. Filibuvir decreases primer extension from PE46 with an IC50 of 73 nM, but has no obvious effect on de novo-initiated RNA synthesis with IC50 of 5 μM[2]. |
別名 | PF-00868554 |
分子量 | 503.64 |
分子式 | C29H37N5O3 |
CAS No. | 877130-28-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 9mg/mL (17.9mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Filibuvir 877130-28-4 Cell Cycle/Checkpoint DNA Damage/DNA Repair Microbiology/Virology Proteases/Proteasome HCV Protease DNA/RNA Synthesis PF-00868554 PF 00868554 PF00868554 Inhibitor inhibitor inhibit