keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 20,500 | |||
5 mg | 在庫あり | ¥ 55,000 | |||
10 mg | 在庫あり | ¥ 87,000 | |||
25 mg | 在庫あり | ¥ 144,500 | |||
50 mg | 在庫あり | ¥ 203,500 | |||
100 mg | 在庫あり | ¥ 273,500 |
説明 | Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM). |
ターゲット&IC50 | FZD7 CRD (human):58 nM (EC50), FZD7 CRD (mouse):34 nM (EC50) |
別名 | (Ac)-LPSDDLEFWCHVMY-NH2 |
分子量 | 1796.03 |
分子式 | C83H114N18O23S2 |
CAS No. | 2247635-23-8 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
You can also refer to dose conversion for different animals. 詳細
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Fz7-21 2247635-23-8 Cytoskeletal Signaling Stem Cells Wnt/beta-catenin lipid-binding groove FZD7 Wnt Fz7 21 (Ac)-LPSDDLEFWCHVMY-NH2 Wnt–β-catenin Fz-7-21 conformation FZD7 CRD intestinal organoids Inhibitor Fz721 inhibit inhibitor