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カタログ番号	製品名	別名	ターゲット
T1532	Pidotimod		Others , Antibacterial
	Pidotimod is a synthetic dipeptide with immunomodulatory properties.		Others , Antibacterial
T5036	Cangrelor tetrasodium		GPR , P2Y Receptor
	Cangrelor tetrasodium is a reversible and selective antagonist of platelet P2Y12, with prompt and potent antiplatelet effects.		GPR , P2Y Receptor
T9592	OATD-01		Others
	OATD-01 is a highly active inhibitor of both Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase).		Others
T12268	NTP42		Prostaglandin Receptor , PPAR
	NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)		Prostaglandin Receptor , PPAR
T6792	BQ-123	BQ123	Endothelin Receptor
	BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.		Endothelin Receptor
T9699	TAK-615		LPA Receptor
	TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors.		LPA Receptor
T6054	GSK256066		PDE
	GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380, 000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.		PDE
T9688	CC-90001		JNK
	CC-90001 is an orally administered c-Jun N-terminal kinase (JNK) inhibitor with bias for JNK1 over JNK2.		JNK
T8313	HCH6-1		Others
	HCH6-1 is a competitive Formyl peptide receptor 1 (FPR1) antagonist.		Others
T11339	Furegrelate sodium	U-63557A	PPAR
			PPAR
T1841	UNC0379		Histone Methyltransferase
	UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.		Histone Methyltransferase
T21712	BAY 41-8543		Others , Guanylate cyclase
	BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).		Others , Guanylate cyclase
T0120	Voriconazole	UK-109496	Antifection , Antifungal
	Voriconazole (UK-109496) is a triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 CYP3A.		Antifection , Antifungal
T30258	AZD-4818	CCR1 antagonist	CCR
	AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.		CCR
T8900	Seralutinib	GB002	PDGFR
	Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.		PDGFR
T23322	SB 452533		TRP/TRPV Channel
	SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).		TRP/TRPV Channel
T4503	Talniflumate	Somalgen	Chloride channel , COX , N-Acetylglucosaminyltransferase , Anion Exchanger
	Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition o...
T22358	Etalocib	LY293111,VML295	Apoptosis , Leukotriene Receptor , LTR
	Etalocib (LY293111) is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of the leukotriene B4 (LTB4) receptor or directly through 5'-l...		Apoptosis , Leukotriene Receptor , LTR
T4016	BMS-986020	AM152,BMS986020	LPA Receptor , LPL Receptor
	BMS-986020 (AM152) is a selective antagonist of LPA1.		LPA Receptor , LPL Receptor
T2561	Macitentan	ACT-064992	Apoptosis , Endothelin Receptor
	Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).		Apoptosis , Endothelin Receptor
T22245	Arformoterol Tartrate	(R,R)-Formoterol tartrate	Adrenergic Receptor
	Arformoterol Tartrate ((R,R)-Formoterol tartrate) is the tartrate salt of arformoterol. Arformoterol is a long-acting beta-2 adrenergic agonist with bronchodilator activity[2].		Adrenergic Receptor
T6445	Cilomilast	SB-207499,Ariflo	PDE
	Cilomilast (SB-207499) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity. Phase 3.		PDE
T14782	Brilaroxazine	RP5063	Dopamine Receptor , 5-HT Receptor
	Brilaroxazine (RP5063) is a potent multimodal dopamine/5-HT modulator. Brilaroxazine is a partial agonist of dopamine D2, D3, and D4 receptors, 5-HT1A (Ki =1.5 nM) and 5-HT2A (Ki = 2.5 nM), and has antagonist activity 5-...		Dopamine Receptor , 5-HT Receptor
T6547	Ipratropium Bromide	Sch 1000,Itrop,Atrovent	AChR
	Ipratropium Bromide (Sch 1000) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis and emphysema.		AChR
T0794	Mepenzolate Bromide	Colibantil,Cantil,Cantilaque	AChR
	Mepenzolate Bromide (Colibantil) is a muscarinic antagonist used to treat gastrointestinal conditions.		AChR
T26795	PXS-4728A	BI-1467335,BI 1467335,BI1467335,BI-1467335 HCl	Monoamine Oxidase
	BI-1467335 HCl(BI 1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive pulmonary disease in mice[2].		Monoamine Oxidase
T0239	Lonidamine	AF1890,DICA,Diclondazolic Acid	Apoptosis , Hexokinase , Mitochondrial Metabolism
	Lonidamine (Diclondazolic Acid) is an indazole carboxylic acid derivative, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK).		Apoptosis , Hexokinase , Mitochondrial Metabolism
T0098	Ipratropium bromide monohydrate	Ipratropium bromide hydrate	AChR
	Ipratropium bromide monohydrate (Ipratropium bromide hydrate) is a muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial...		AChR
T21389	Enprofylline	Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum	Others
	Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of sick...		Others
T8236	RHC 80267	U-57908	Others , Phospholipase , COX , Acyltransferase , AChR
	RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)		Others , Phospholipase , COX , Acyltransferase , AChR
T2663	GTS-21 dihydrochloride	GTS 21 dihydrochloride,DMXB-A,DMBX-anabaseine	5-HT Receptor , AChR
	GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh.		5-HT Receptor , AChR
TP1016L	Aviptadil Acetate	Vasoactive Intestinal Peptide acetate salt	RAAS , SARS-CoV
	Aviptadil Acetate (Vasoactive Intestinal Peptide acetate salt) induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs and platelet aggregation. Avitadil acetate can be used for research on pulmona...		RAAS , SARS-CoV
T3034	Eprazinone dihydrochloride	Resplen,Mucitux,Eftapan,NSC 317935,Eprazinone 2HCl	Others , Neurokinin receptor
	Eprazinone dihydrochloride (NSC 317935) is a mucolytic with antitussive and mucolytic effect.		Others , Neurokinin receptor
T1083L	Theophylline monohydrate	Quibron	HDAC , PDE , Adenosine Receptor
	Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Theophylline monohydrate is a ...		HDAC , PDE , Adenosine Receptor
T9199	GLPG2938	1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea	S1P Receptor , LPL Receptor
	GLPG2938 (1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea) is a potent and selective antagonist of S1P2.		S1P Receptor , LPL Receptor
T3148	MK-571 sodium	L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid	Leukotriene Receptor , LTR
	MK-571 sodium (L-660711 sodium salt) is a selective, orally active antagonist of the CysLT1 receptor. MK-571 sodium is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the role of Mrp2 in the ...		Leukotriene Receptor , LTR
T60388	MIF098		Others
	MIF098 is a macrophage migration inhibitory factor (MIF) antagonist.MIF098, inhibits pulmonary hypertension associated with SLE and inhibits pulmonary smooth muscle cell (PASMC) proliferation and migration.MIF098 may be ...		Others
T3216	Selexipag	NS-304,ACT-293987,Uptravi	Others , Prostaglandin Receptor
	Selexipag (ACT-293987)(NS-304) is prostacyclin receptor agonist that causes vasodilation in pulmonary vasculature and is used in the therapy of pulmonary arterial hypertension (PAH).		Others , Prostaglandin Receptor
T34387	Ronomilast	ELB353,ELB 353,ELB-353,Elbimilast
	Ronomilast(Elbimilast, ELB 353) is a PDE4 inhibitor for chronic inflammatory disease. Ronomilast is developed to treat chronic obstructive pulmonary disease (COPD).
T83168	Aderamastat	FP-025	MMP
	Aderamastat (FP-025) is an orally active inhibitor of matrix metalloproteinase 12 (MMP-12), utilized in the research of conditions such as asthma, chronic obstructive pulmonary disease (COPD), and pulmonary fibrosis [1].		MMP
T33386	Milveterol HCl	Milveterol,GSK-159797,GSK 159797,GSK159797	Adrenergic Receptor
	Milveterol HCl is a long-acting β(2) -adrenergic receptor agonist for the potential treatment of chronic obstructive pulmonary disease (COPD).		Adrenergic Receptor
T26760	Bedoradrine sulfate	KUR1246,MN 221 sulfate,KUR1246 sulfate,MN221 sulfate,KUR 1246 sulfate,MN-221 sulfate,KUR 1246,KUR-1246 sulfate,MN-221,MN 221,MN221,KUR-1246	Adrenergic Receptor
	Bedoradrine sulfate (MN-221 sulfate) is a super-selective beta2 agonist for the treatment of asthma exacerbations and chronic obstructive pulmonary disease.		Adrenergic Receptor
T72031	BI 1015550		PDE
	BI 1015550 is an orally active inhibitor of PDE4B with an IC 50 value of 7.2 nM. BI 1015550 has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmo...		PDE
T4041	Ziritaxestat	GLPG1690	PDE
	Ziritaxestat (GLPG1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in idiopathic pulmonary fibrosis patients.		PDE
T30232	AWD 12-281	GSK 842470,GSK-842470,AWD12-281,AWD-12-281,GW 842470	PDE
	AWD 12-281 is a selective phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory and bronchodilator activity used in the study of chronic obstructive pulmonary disease (COPD).		PDE
T12850	Dilmapimod	SB-681323,GW 681323	p38 MAPK , Autophagy
	Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.		p38 MAPK , Autophagy
T9877	Tiquizium		AChR
	Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.		AChR
T69665	Zelasudil	RXC007	ROCK
	Zelasudil (RXC007) is a Rho-related (ROCK) kinase inhibitor for the study of idiopathic pulmonary fibrosis and inflammation.		ROCK
T6147	Nortadalafil	Demethyl Tadalafil	PDE
	Nortadalafil (Demethyl Tadalafil) is demethyl Tadalafil, which is a PDE5 inhibitor, treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.		PDE
T60226	CT52923		PDGFR
	CT52923 is a selective, orally active antagonist of platelet-derived growth factor receptor (PDGFR), functioning as an ATP-competitive inhibitor. It has versatile applications for researching an array of pathological dis...		PDGFR

Compounds

Pidotimod

T1532

Synonym:

Target: Others, Antibacterial

cangrelor tetrasodium

T5036

Synonym:

Target: GPR, P2Y Receptor

Target: Prostaglandin Receptor, PPAR

BQ-123

T6792

Synonym: BQ123

Target: Endothelin Receptor

Target: Histone Methyltransferase

BAY 41-8543

T21712

Synonym:

Target: Others, Guanylate cyclase

Voriconazole

T0120

Synonym: UK-109496

Target: Antifection, Antifungal

AZD-4818

T30258

Synonym: CCR1 antagonist

Target: TRP/TRPV Channel

Talniflumate

T4503

Synonym: Somalgen

Target: Chloride channel, COX, N-Acetylglucosaminyltransferase, Anion Exchanger

Etalocib

T22358

Synonym: LY293111,VML295

Target: Apoptosis, Leukotriene Receptor, LTR

BMS-986020

T4016

Synonym: AM152,BMS986020

Target: LPA Receptor, LPL Receptor

Macitentan

T2561

Synonym: ACT-064992

Target: Apoptosis, Endothelin Receptor

Arformoterol Tartrate

T22245

Synonym: (R,R)-Formoterol tartrate

Target: Adrenergic Receptor

Cilomilast

T6445

Synonym: SB-207499,Ariflo

Target: Dopamine Receptor, 5-HT Receptor

Ipratropium Bromide

T6547

Synonym: Sch 1000,Itrop,Atrovent

Target: AChR

Mepenzolate Bromide

T0794

Synonym: Colibantil,Cantil,Cantilaque

Target: AChR

PXS-4728A

T26795

Synonym: BI-1467335,BI 1467335,BI1467335,BI-1467335 HCl

Target: Monoamine Oxidase

Lonidamine

T0239

Synonym: AF1890,DICA,Diclondazolic Acid

Target: Apoptosis, Hexokinase, Mitochondrial Metabolism

Ipratropium bromide monohydrate

T0098

Synonym: Ipratropium bromide hydrate

Target: AChR

Enprofylline

T21389

Synonym: Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum

Target: Others, Phospholipase, COX, Acyltransferase, AChR

GTS-21 dihydrochloride

T2663

Synonym: GTS 21 dihydrochloride,DMXB-A,DMBX-anabaseine

Target: 5-HT Receptor, AChR

Aviptadil Acetate

TP1016L

Synonym: Vasoactive Intestinal Peptide acetate salt

Target: RAAS, SARS-CoV

Eprazinone dihydrochloride

T3034

Synonym: Resplen,Mucitux,Eftapan,NSC 317935,Eprazinone 2HCl

Target: Others, Neurokinin receptor

Theophylline monohydrate

T1083L

Synonym: Quibron

Target: HDAC, PDE, Adenosine Receptor

GLPG2938

T9199

Synonym: 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea

Target: S1P Receptor, LPL Receptor

MK-571 sodium

T3148

Synonym: L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid

Target: Leukotriene Receptor, LTR

Synonym: NS-304,ACT-293987,Uptravi

Target: Others, Prostaglandin Receptor

Ronomilast

T34387

Synonym: ELB353,ELB 353,ELB-353,Elbimilast

Synonym: Milveterol,GSK-159797,GSK 159797,GSK159797

Target: Adrenergic Receptor

Bedoradrine sulfate

T26760

Synonym: KUR1246,MN 221 sulfate,KUR1246 sulfate,MN221 sulfate,KUR 1246 sulfate,MN-221 sulfate,KUR 1246,KUR-1246 sulfate,MN-221,MN 221,MN221,KUR-1246

Target: Adrenergic Receptor

Synonym: GSK 842470,GSK-842470,AWD12-281,AWD-12-281,GW 842470

Target: PDE

Dilmapimod

T12850

Synonym: SB-681323,GW 681323

Target: p38 MAPK, Autophagy

Synonym: Demethyl Tadalafil

カタログ番号	製品名	別名	ターゲット
TN1355	Acanthoside B		Immunology/Inflammation related
	Acanthoside B is a lignan with anti-inflammatory and anti-amnesic effects. Acanthoside B can be used for studies about Alzheimer's disease and lung inflammation.		Immunology/Inflammation related
T5758	Sphondin		COX , Prostaglandin Receptor
	Sphondin has anticonvulsant, anti-inflammatory, and anti-proliferative activities, it possessed an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells.		COX , Prostaglandin Receptor
T3409	Plantamajoside	Y0160,C10485	Others
	Plantamajoside (Y0160) has anti-hepatotoxic, anti-inflammatory, antinociceptive activities, improving sexual function and antioxidant activity.		Others
T2223	Kinetin	6-Furfuryladenine,N6-Furfuryladenine	Others
	Kinetin (N6-Furfuryladenine), a type of cytokinin, has plant growth regulation effects.		Others
T1083	Theophylline	Theo-24,1,3-Dimethylxanthine	Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy
	Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3...
T0518	Methacycline hydrochloride	Rondomycin,Methacycline HCl	ribosome , Antibacterial , Antibiotic
	Methacycline hydrochloride (Rondomycin) is a broad-spectrum semisynthetic antibiotic related to TETRACYCLINE but excreted more slowly and maintaining effective blood levels for a more extended period.		ribosome , Antibacterial , Antibiotic
T3S0401	Piceatannol 3'-O-glucoside	Piceatannol 3-glycoside,Quzhaqigan	Arginase , NO Synthase
	Piceatannol 3'-O-glucoside (Piceatannol 3-glycoside) increases pulmonary blood oxygen tension and decreases pulmonary interstitial edema, so it can protect lung injury.		Arginase , NO Synthase
T1680	Tolazoline hydrochloride	Imidaline hydrochloride,Imidaline (hydrochloride),Benzidazol hydrochloride,Tolazoline HCl,NSC35110 (hydrochloride)	Adrenergic Receptor
	Tolazoline hydrochloride (NSC35110 (hydrochloride)) is a non-selective competitive α-adrenergic receptor antagonist used in treatment of persistent pulmonary hypertension of the newborn.		Adrenergic Receptor
T2803	Monocrotaline	Crotaline	TGF-beta/Smad
	Monocrotaline (Crotaline) is a pyrrolizidine alkaloid and a toxic plant constituent that poisons livestock and humans through the ingestion of contaminated grains and other foods. The alkaloid causes pulmonary artery hyp...		TGF-beta/Smad
T6S0105	Peiminine	Zhebeinone,Fritillarine,Raddeanine,Verticinone	Others , Autophagy
	1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.		Others , Autophagy
T6S0119	Dauricine		Apoptosis , Others , NF-κB
	1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important ro...		Apoptosis , Others , NF-κB
T3821	Deapioplatycodin D	Deapi-platycodin D,DesapioplatycodinD	Others , HCV Protease
	Deapioplatycodin D and platycodin D can regulate the production and secretion of airway mucin and, at least in part, explains the traditional use of aqueous extract of APG as expectorants in diverse inflammatory pulmonar...		Others , HCV Protease
T3S2007	MRE-269	MRE 269,ACT-333679,MRE269	Prostaglandin Receptor
	MRE-269 (ACT-333679) is an orally available and long-acting prostacyclin receptor agonist prodrug. MRE-269(ACT-333679) is used for the treatment of pulmonary arterial hypertension. MRE-269(ACT-333679) is an active metabo...		Prostaglandin Receptor
TN2089	Platycodin D3		HCV Protease , NF-κB
	Platycodin D3 is a NF-κB inhibitor, it could as expectorants in diverse inflammatory pulmonary diseases, it can regulate the production and secretion of airway mucin; it can significantly enhance mitogen- and OVA-induced...		HCV Protease , NF-κB
T2S0690	Ecliptasaponin A	Echinocystic acid-3-o-glucoside	Others
	1. Ecliptasaponin A (Echinocystic acid-3-o-glucoside) has protective effects against the pulmonary fibrosis induced by bleomycin via reducing the oxidative stress, lung tissue inflammation, and the subsequent epithelial-...		Others
T2946	Tanshinone IIA sulfonate sodium	Tanshinone IIA sulfonate,Sodium Tanshinone IIA sulfonate,Tanshinone IIA sodium sulfonate,sodium	CaMK , P450 , Calcium Channel
	Tanshinone IIA sulfonate sodium (Tanshinone IIA sodium sulfonate) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human purinergic receptor...		CaMK , P450 , Calcium Channel
T4953	Neotuberostemonine		NOS
	Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruit...		NOS
T4S1102	Liensinine diperchlorate	Liensinine-Perchlorate	Mitophagy , Others , Autophagy
	Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus. It inhibits late autophagy by blocking autophagosome-lysosome fusion and exhibits biological activities such as...		Mitophagy , Others , Autophagy
T6S1049	Wilforine		ATPase
	Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect, which might be medi...		ATPase
TN1936	Mogroside III-E		IL Receptor , TNF , TLR
	Mogroside III-E is a cucurbitane-type compound isolated from Siraitia grosvenorii, has anti-inflammatory activity, it attenuates LPS-induced acute lung injury in mice partly through regulation of the TLR4/MAPK/NF-κB axis...		IL Receptor , TNF , TLR
TN3469	Aucuparin	2,6-dimethoxy-4-phenylphenol	NADPH-oxidase
	Aucuparin (2,6-dimethoxy-4-phenylphenol) is a plant antibiotic with anti-inflammatory activity. Aucuparin inhibited pulmonary fibrosis in mouse models induced by bleomycin (BLM). ABTS and FRAP showed clear scavenging act...		NADPH-oxidase
T4973	Paraxanthine	1,7-DIMETHYLXANTHINE	Endogenous Metabolite
	Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is struc...		Endogenous Metabolite
T3795	Corilagin		Apoptosis , TLR , Reverse Transcriptase , Antibacterial , Autophagy
	Corilagin has anti-inflammatory activity. Corilagin has a significant antitumour potential and lower toxicity in normal cells in vitro.Corilagin can enhance the cytotoxicity of both cisplatin and doxorubicin on the Hep3B...
T4S2063	Tetrahydrocoptisine	STYLOPINE	ERK , p38 MAPK , NF-κB
	1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may invo...		ERK , p38 MAPK , NF-κB
T40634	Perilla ketone
	Perilla ketone is a naturally occurring xenobiotic compound that undergoes activation by pulmonary P450 cytochrome enzymes within the lung. This activation leads to the manifestation of severe pulmonary damage and the de...
TN4654	Niazirin		Others
	The Moringa oleifera extract(including niaziridin and Niazirin) can successfully attenuate the development of pulmonary hypertension via direct vasodilatation and a potential increase in antioxidant activity.		Others
T20636	Latrunculin B	LAT-B,LATB,NSC 339663,NSC339663,NSC-339663,LAT B,INS115644	Antifungal
	Latrunculin B, an alkaloid from the Red Sea sponge, is an actin polymerization inhibitor with antifungal and antiprotozoal activity.Latrunculin B modulates the electrophysiological characteristics of the pulmonary veins ...		Antifungal
TN1806	Isotetrandrine		IL Receptor , NF-κB , MAPK
	Isotetrandrine is a small molecule inhibitor, on various aspects of LPS-induced inflammation in vitro and in vivo. It dose-dependently suppresses the severity of LPS-induced ALI by inactivation of MAPK and NF-κB, which m...		IL Receptor , NF-κB , MAPK

天然物製品

Acanthoside B

TN1355

Synonym:

Target: Immunology/Inflammation related

sphondin

T5758

Synonym:

Target: COX, Prostaglandin Receptor

Plantamajoside

T3409

Synonym: Y0160,C10485

Target: Others

Kinetin

T2223

Synonym: 6-Furfuryladenine,N6-Furfuryladenine

Target: Others

Theophylline

T1083

Synonym: Theo-24,1,3-Dimethylxanthine

Target: Endogenous Metabolite, HDAC, PDE, Adenosine Receptor, Autophagy

Methacycline hydrochloride

T0518

Synonym: Rondomycin,Methacycline HCl

Target: ribosome, Antibacterial, Antibiotic

Piceatannol 3'-O-glucoside

T3S0401

Synonym: Piceatannol 3-glycoside,Quzhaqigan

Target: Arginase, NO Synthase

Tolazoline hydrochloride

T1680

Synonym: Imidaline hydrochloride,Imidaline (hydrochloride),Benzidazol hydrochloride,Tolazoline HCl,NSC35110 (hydrochloride)

Target: Adrenergic Receptor

Monocrotaline

T2803

Synonym: Crotaline

Target: TGF-beta/Smad

Peiminine

T6S0105

Synonym: Zhebeinone,Fritillarine,Raddeanine,Verticinone

Target: Others, Autophagy

Dauricine

T6S0119

Synonym:

Target: Apoptosis, Others, NF-κB

Deapioplatycodin D

T3821

Synonym: Deapi-platycodin D,DesapioplatycodinD

Target: Others, HCV Protease

MRE-269

T3S2007

Synonym: MRE 269,ACT-333679,MRE269

Target: Prostaglandin Receptor

Platycodin D3

TN2089

Synonym:

Target: HCV Protease, NF-κB

Ecliptasaponin A

T2S0690

Synonym: Echinocystic acid-3-o-glucoside

Target: Others

Tanshinone IIA sulfonate sodium

T2946

Synonym: Tanshinone IIA sulfonate,Sodium Tanshinone IIA sulfonate,Tanshinone IIA sodium sulfonate,sodium

Target: CaMK, P450, Calcium Channel

Liensinine diperchlorate

T4S1102

Synonym: Liensinine-Perchlorate

Target: Mitophagy, Others, Autophagy

Target: IL Receptor, TNF, TLR

Aucuparin

TN3469

Synonym: 2,6-dimethoxy-4-phenylphenol

Target: NADPH-oxidase

Paraxanthine

T4973

Synonym: 1,7-DIMETHYLXANTHINE

Target: Endogenous Metabolite

Corilagin

T3795

Synonym:

Target: Apoptosis, TLR, Reverse Transcriptase, Antibacterial, Autophagy

Tetrahydrocoptisine

T4S2063

Synonym: STYLOPINE

Target: ERK, p38 MAPK, NF-κB

Synonym: LAT-B,LATB,NSC 339663,NSC339663,NSC-339663,LAT B,INS115644

Target: IL Receptor, NF-κB, MAPK

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00527	SP-D Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Surfactant Pulmonary-Associated Protein D (SP-D) is a 43 kDa member of the collectin family of innate immune modulators. Its principal components consist of a collagen-like region and a C-terminal carbohydrate recognitio...
TMPY-02869	MMP-12 Protein, Human, Recombinant (catalytic domain)	Human	E. coli
	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPY-02062	SULT1A1 Protein, Human, Recombinant (His)	Human	E. coli
	Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroid...
TMPY-00566	CCL18 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its...
TMPY-01442	DMBT1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB d...
TMPJ-01129	SMAD1 Protein, Human, Recombinant (GST)	Human	E. coli
	SMAD Family Member 1 (SMAD1) is a member of the dwarfin/SMAD family. SMAD1 has the highest expression in the heart and skeletal muscle, containing one MAD homology 1 domain and one MAD homology 2 domain, As a transcripti...
TMPH-01979	SFTPB Protein, Human, Recombinant	Human	P. pastoris (Yeast)
	Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearl...
TMPY-06810	SFTPB Protein, Human, Recombinant (His)	Human	CHO Cells
	Pulmonary surfactant-associated protein B, also known as SFTPB and SP-B, contains one saposin A-type domain and three saposin B-type domains. SP-B is produced primarily by alveolar type II cells (AEC2) but also by noncil...
TMPK-00867	EMAP-II/AIMP1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	The potent antiangiogenic and proinflammatory protein Endothelial Monocyte Activating Polypeptide II (EMAP II) has been described as a mediator of pulmonary vascular and alveolar formation and its expression is inversely...
TMPJ-01146	LGALSL Protein, Human, Recombinant (His)	Human	E. coli
	Galectin-Related Protein (LGALSL) is a 172 amino acid protein that contains one Galectin domain. LGALSL does not appear to bind carbohydrates or lactose as the critical residues required for binding are not conserved. LG...
TMPY-04321	CHRNA5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in ...
TMPH-01080	Ceruloplasmin Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the ...
TMPJ-00361	Endoglin Protein, Human, Recombinant (Trx & His)	Human	E. coli
	Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, a...
TMPY-01481	FLAP Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP), also known as FLAP, belongs to the MAPEG family. ALOX5AP/FLAP is an essential partner of 5-LO for this process. The FLAP (ALOX5AP) gene has been linked to risk fo...
TMPJ-00505	Serpin A1 Protein, Human, Recombinant (aa 25-418, His)	Human	HEK293 Cells
	Serpin A1 is a prototype member of the Serpin superfamily of the serine protease inhibitors. As one of the most abundant proteinase inhibitors in the circulation, it is synthesized in hepatocytes, and to a lesser extent,...
TMPJ-00011	CXCL2 Protein, Mouse, Recombinant	Mouse	E. coli
	C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin...
TMPU-00002	SOS1-Cat Protein, Human, Recombinant (His)	Human	E. coli
	Defects in SOS1 are the cause of gingival fibromatosis 1 (GGF1) [MIM:135300]; also known as GINGF1. Gingival fibromatosis is a rare overgrowth condition. Defects in SOS1 are the cause of Noonan syndrome type 4 (NS4) [MIM...
TMPH-02841	Prohibitin Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regul...
TMPJ-00362	MMP-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. Matrix metallo...
TMPY-01303	Serpin A3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has be...
TMPH-02690	PLA2G10 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatid...

SP-D Protein, Human, Recombinant (His)

TMPJ-00527

Species: Human

Expression System: HEK293 Cells

MMP-12 Protein, Human, Recombinant (catalytic domain)

TMPY-02869

Species: Human

Expression System: E. coli

SULT1A1 Protein, Human, Recombinant (His)

TMPY-02062

Species: Human

Expression System: E. coli

CCL18 Protein, Human, Recombinant (His)

TMPY-00566

Species: Human

Expression System: P. pastoris (Yeast)

DMBT1 Protein, Human, Recombinant (His)

TMPY-01442

Species: Human

Expression System: HEK293 Cells

SMAD1 Protein, Human, Recombinant (GST)

TMPJ-01129

Species: Human

Expression System: E. coli

SFTPB Protein, Human, Recombinant

TMPH-01979

Species: Human

Expression System: P. pastoris (Yeast)

SFTPB Protein, Human, Recombinant (His)

TMPY-06810

Species: Human

Expression System: CHO Cells

EMAP-II/AIMP1 Protein, Mouse, Recombinant (His)

TMPK-00867

Species: Mouse

Expression System: E. coli

LGALSL Protein, Human, Recombinant (His)

TMPJ-01146

Species: Human

Expression System: E. coli

CHRNA5 Protein, Human, Recombinant (His)

TMPY-04321

Species: Human

Expression System: HEK293 Cells

Ceruloplasmin Protein, Human, Recombinant (His & Myc)

TMPH-01080

Species: Human

Expression System: E. coli

Endoglin Protein, Human, Recombinant (Trx & His)

TMPJ-00361

Species: Human

Expression System: E. coli

FLAP Protein, Human, Recombinant (His)

TMPY-01481

Species: Human

Expression System: Baculovirus Insect Cells

Serpin A1 Protein, Human, Recombinant (aa 25-418, His)

TMPJ-00505

Species: Human

Expression System: HEK293 Cells

CXCL2 Protein, Mouse, Recombinant

TMPJ-00011

Species: Mouse

Expression System: E. coli

SOS1-Cat Protein, Human, Recombinant (His)

TMPU-00002

Species: Human

Expression System: E. coli

Prohibitin Protein, Mouse, Recombinant (His)

TMPH-02841

Species: Mouse

Expression System: E. coli

MMP-2 Protein, Human, Recombinant (His)

TMPJ-00362

Species: Human

Expression System: HEK293 Cells

Serpin A3 Protein, Human, Recombinant (His)

TMPY-01303

Species: Human

Expression System: HEK293 Cells

PLA2G10 Protein, Mouse, Recombinant (His & Myc)

TMPH-02690

Species: Mouse

Expression System: E. coli

カタログ番号	製品名
L2200	Tyrosine Kinase Inhibitor Library	1016 compounds
	A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases;
L8500	HIF-1 Signaling Pathway Compound Library	1336 compounds
	A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；

ライブラリー

Tyrosine Kinase Inhibitor Library

L2200

Compounds: 1016

HIF-1 Signaling Pathway Compound Library

L8500

Compounds: 1336