Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GNE-490 is an effective inhibitor of pan-PI3K with IC50s of 3.5 nM, 25 nM, 5.2 nM, 15 nM for PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ, respectively. GNE-490 has >200 fold selectivity for mTOR (IC50 = 750 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 29,500 | |||
5 mg | 在庫あり | ¥ 80,000 | |||
10 mg | 在庫あり | ¥ 129,500 | |||
25 mg | 在庫あり | ¥ 204,500 | |||
50 mg | 在庫あり | ¥ 282,500 | |||
100 mg | 在庫あり | ¥ 383,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 82,500 |
説明 | GNE-490 is an effective inhibitor of pan-PI3K with IC50s of 3.5 nM, 25 nM, 5.2 nM, 15 nM for PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ, respectively. GNE-490 has >200 fold selectivity for mTOR (IC50 = 750 nM). |
分子量 | 386.47 |
分子式 | C18H22N6O2S |
CAS No. | 1033739-92-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (129.38 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
GNE-490 1033739-92-2 Others PI3K/Akt/mTOR signaling PI3K PI3Kβ PI3Kδ Mammalian target of Rapamycin mTOR MCF7.1 PI3Kα Phosphoinositide 3-kinase GNE 490 PI3Kγ breast cancer Inhibitor GNE490 inhibit inhibitor