Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. 3. Ginsenoside Rg5 can ameliorate lung inflammation possibly by inhibiting the binding of LPS to toll-like receptor (TLR)-4 on macrophages. 4. Ginsenoside Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogenesis and improving hypertension without adverse effects in the vasculature. 5. Ginsenoside Rg5 blocks cell cycle of SK-HEP-1 cells at the Gl/S transition phase by down-regulating cyclin E-dependent kinase activity and that the down-regulation of cyclin E-dependent kinase activity is caused mainly by induced CDK2 inhibitor, p21Cip/WAF1 and decreased levels of cyclin E.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 26,500 | |||
5 mg | 在庫あり | ¥ 64,000 | |||
10 mg | 在庫あり | ¥ 103,000 | |||
25 mg | 在庫あり | ¥ 170,000 | |||
50 mg | 在庫あり | ¥ 226,500 | |||
100 mg | 在庫あり | ¥ 319,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 87,000 |
説明 | 1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. 3. Ginsenoside Rg5 can ameliorate lung inflammation possibly by inhibiting the binding of LPS to toll-like receptor (TLR)-4 on macrophages. 4. Ginsenoside Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogenesis and improving hypertension without adverse effects in the vasculature. 5. Ginsenoside Rg5 blocks cell cycle of SK-HEP-1 cells at the Gl/S transition phase by down-regulating cyclin E-dependent kinase activity and that the down-regulation of cyclin E-dependent kinase activity is caused mainly by induced CDK2 inhibitor, p21Cip/WAF1 and decreased levels of cyclin E. |
ターゲット&IC50 | IGF-1:90 nM |
植物由来 |
分子量 | 767 |
分子式 | C42H70O12 |
CAS No. | 186763-78-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
You can also refer to dose conversion for different animals. 詳細
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Ginsenoside Rg5 186763-78-0 Immunology/Inflammation Neuroscience NF-Κb Tyrosine Kinase/Adaptors NF-κB COX IGF-1R Nuclear factor-κB Inhibitor Cyclooxygenase Ginsenoside Rg 5 Nuclear factor-kappaB inhibit Ginsenoside Rg-5 inhibitor