Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
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1 mg | 在庫あり | ¥ 41,000 | |||
5 mg | 在庫あり | ¥ 103,000 | |||
10 mg | 在庫あり | ¥ 151,500 | |||
25 mg | 在庫あり | ¥ 226,500 | |||
50 mg | 在庫あり | ¥ 319,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 114,000 |
説明 | Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR). |
In vitro | In the liver, obeticholic acid undergoes conjugation with glycine to produce glyco-obeticholic acid, subsequently secreted into bile. Upon reaching the ileum and colon, microorganisms deconjugate this compound back into its original form, obeticholic acid, facilitating its reabsorption or fecal excretion. |
分子量 | 477.68 |
分子式 | C28H47NO5 |
CAS No. | 863239-60-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (104.67 mM)
You can also refer to dose conversion for different animals. 詳細
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Glyco-Obeticholic acid 863239-60-5 Metabolism FXR NR1H4 Inhibitor ileum colon microorganisms GlycoObeticholic acid Glyco Obeticholic acid metabolite,liver inhibit inhibitor