Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacolchiside A1 shows antiproliferation activities in three cancer cell lines with the IC50 value of 2.4 uM, it exhibits a preferential cytotoxicity on a pigmented melanoma cell line. It suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 16,500 | |||
5 mg | 在庫あり | ¥ 38,000 | |||
10 mg | 在庫あり | ¥ 56,500 | |||
25 mg | 在庫あり | ¥ 95,000 | |||
50 mg | 在庫あり | ¥ 141,000 | |||
100 mg | 在庫あり | ¥ 200,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 64,000 |
説明 | Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacolchiside A1 shows antiproliferation activities in three cancer cell lines with the IC50 value of 2.4 uM, it exhibits a preferential cytotoxicity on a pigmented melanoma cell line. It suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway. |
植物由来 |
別名 | Raddeanoside R13 |
分子量 | 897.1 |
分子式 | C47H76O16 |
CAS No. | 106577-39-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 83.3 mg/mL (92.89 mM ), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Hederacolchiside A1 106577-39-3 Apoptosis Cytoskeletal Signaling MAPK Microbiology/Virology PI3K/Akt/mTOR signaling ERK mTOR Parasite MEK Akt PI3K Mammalian target of Rapamycin Phosphoinositide 3-kinase Inhibitor PKB inhibit Protein kinase B Hederacolchiside A 1 Hederacolchiside A-1 Raddeanoside R13 inhibitor