Powder: -20°C for 3 years | In solvent: -80°C for 1 year
IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 10,000 | |||
25 mg | 在庫あり | ¥ 18,000 | |||
50 mg | 在庫あり | ¥ 29,000 | |||
100 mg | 在庫あり | ¥ 45,500 | |||
200 mg | 在庫あり | ¥ 77,500 | |||
500 mg | 在庫あり | ¥ 122,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 7,000 |
説明 | IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM). |
ターゲット&IC50 | IDO1:10 nM |
In vitro | In an immunologically active mouse model, INCB024360 effectively inhibited tumor growth. Similarly, in mice bearing GM-CSF-secreting B16 tumors, INCB024360 (75 mg/kg b.i.d) demonstrated dose-dependent tumor growth suppression. |
In vivo | INCB024360 significantly inhibits IDO1 in HeLa cells (IC50 = 19 nM) and promotes differentiation in CD4+ T cells, CD8+ T cells, and NK cells. |
別名 | INCB024360 analogue, INCB14943 |
分子量 | 271.64 |
分子式 | C9H7ClFN5O2 |
CAS No. | 914471-09-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 27.2 mg/mL (100 mM)
DMSO: 27.2 mg/mL (100 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
IDO5L 914471-09-3 Metabolism Indoleamine 2,3-Dioxygenase (IDO) IDO INCB-14943 Inhibitor inhibit INCB 14943 IDO-5L INCB024360 analogue INCB14943 inhibitor