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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T11616 | IDO-IN-13 | GS-4361 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
IDO-IN-13 (GS-4361) is a potent indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor (EC50: 17 nM). | |||
T11615 | IDO-IN-12 | IDO , Indoleamine 2,3-Dioxygenase (IDO) | |
IDO-IN-12 is an inhibitor of indoleamine 2,3-dioxygenase (IDO). | |||
T7181 | IDO-IN-1 | Indoleamine 2,3-Dioxygenase (IDO) | |
IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays, respectively.) | |||
T7660 | IDO inhibitor 1 | Indoleamine 2,3-Dioxygenase (IDO) | |
IDO inhibitor 1 is an potent inhibitor of indoleamine-2,3 dioxygenase (IDO) ( IC50 <100 nM).with potential immunomodulating and antineoplastic activities. | |||
T1806 | IDO-IN-7 | NLG919,Navoximod,NLG-919 analogue,GDC-0919 | Indoleamine 2,3-Dioxygenase (IDO) |
IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor. | |||
T4142 | PCC0208009 | IDO inhibitor 1,DO-IN-2,IDO-IN-2 | Indoleamine 2,3-Dioxygenase (IDO) |
PCC0208009 (IDO-IN-2) is an IDO inhibitor. | |||
T40093 | IDO-IN-15 | ||
IDO-IN-15 is an IDO1 inhibitor ( IC 50 < 0.51 nM). | |||
T3548 | Epacadostat | INCB 024360,IDO Inhibitor 1 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
Epacadostat (INCB 024360) is an oral-available inhibitor of indoleamine 2, 3-dioxygenase (IDO1), increasing the proliferation and activation of various immune cells and reducing tumor-associated regulatory T cells. | |||
T11622 | IDO-IN-9 | IDO | |
IDO-IN-9 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50s of 0.011 μM (Kinase) and 0.0018 μM (Hela Cell). | |||
T11617 | IDO-IN-3 | IDO | |
IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 290 nM). | |||
T11621 | IDO-IN-8 | NLG-1487 | IDO |
IDO-IN-8 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM). | |||
T11614 | IDO-IN-11 | IDO | |
IDO-IN-11 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50s of 0.18 μM (Kinase) and 0.014 μM (Hela Cell). | |||
T11618 | IDO-IN-4 | Others | |
IDO-IN-4 is an indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor. | |||
T11623 | IDO/TDO-IN-1 | Others | |
IDO/TDO-IN-1 is an orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50s: 9.7 and 47 nM). | |||
T11620 | IDO-IN-6 | NLG-1486 | IDO |
IDO-IN-6 is an indoleamine 2,3-dioxygenase (IDO) inhibitor. | |||
T11619 | IDO-IN-5 | NLG-1489 | IDO |
IDO-IN-5 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM). | |||
T74536 | IDO/Tubulin-IN-2 | ||
IDO/Tubulin-IN-2 (HT2) is a powerful inhibitor of both TDO and tubulin. This compound demonstrates significant efficacy against various cancer cell lines, including U87, HepG2, A549, HCT-116, and LO2, with respective IC5... | |||
T62270 | IDO-IN-14 | ||
IDO-IN-14 is an IDO inhibitor (IC50: 0.6928 nM). | |||
T62130 | IDO-IN-16 | ||
IDO-IN-16 (compound 5) is an IDO inhibitor (IC50: 36 nM). | |||
T11626 | IACS-8968 | IDO/TDO Inhibitor | IDO |
IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO). | |||
T11901 | IDO1-IN-5 | IDO , Indoleamine 2,3-Dioxygenase (IDO) | |
IDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1. | |||
T11627 | IACS-8968 R-enantiomer | IDO/TDO Inhibitor (R-enantiomer) | IDO |
IACS-8968 R-enantiomer is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO). | |||
T11628 | IACS-8968 S-enantiomer | IDO/TDO Inhibitor (S-enantiomer) | IDO |
IACS-8968 S-enantiomer is the S-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO). | |||
T2647 | IDO5L | INCB024360 analogue,INCB14943 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM). | |||
T9164 | BMS-986242 | BMS986242 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer. | |||
T10199 | GNF-PF-3777 | 8-Nitrotryptanthrin | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
GNF-PF-3777 (8-Nitrotryptanthrin) (8-Nitrotryptanthrin) is a potent inhibitor of human indoleamine 2,3-dioxygenase 2 (hIDO2; Ki: 0.97 μM). | |||
T4532 | Linrodostat | BMS-986205 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
Linrodostat (BMS-986205) is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor. | |||
TQ0071 | Navoximod | GDC-0919,NLG-919 | Indoleamine 2,3-Dioxygenase (IDO) |
Navoximod (GDC-0919) (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM). | |||
T4307 | PF-06840003 | EOS200271,PF 06840003 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
PF-06840003 (EOS200271) is a specific and oral active IDO-1 inhibitor. | |||
T1847 | Necrostatin-1 | Nec-1,Necrostatin 1 | Indoleamine 2,3-Dioxygenase (IDO) , Ferroptosis , Autophagy , RIP kinase |
Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin-1 also inhibits IDO. | |||
T20513 | IDO1-IN-1 | IDO1 inhibitor 1,2 HzBTZ,IDO1IN1,2-HzBTZ,IDO1-inhibitor-1 | IDO |
IDO1-IN-1 (2 HzBTZ) is an indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor. | |||
T6543 | Indoximod | NLG-8189,Indoximod (NLG-8189),1-Methyl-D-tryptophan | Indoleamine 2,3-Dioxygenase (IDO) |
Indoximod (Indoximod (NLG-8189)) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan... | |||
T11624 | IDO1-IN-2 | IDO | |
T11625 | IDO1 and HDAC1 Inhibitor | Others | |
IDO1 and HDAC1 Inhibitor is a dual IDO1 and HDAC1 inhibitor (IC50s: 69.0 nM and 66.5 nM). | |||
T12801 | (S)-IDO1-IN-5 | Others | |
(S)-IDO1-IN-5 is an active S-isomer of IDO1-IN-5. (S)-IDO1-IN-5 binds to IDOL(IC50 value less than 1.5 µΜ). | |||
T12668 | (Rac)-IDO1-IN-5 | Others | |
(Rac)-IDO1-IN-5 is a racemate of IDO1-IN-5, a potent, selective, and brain-penetrating inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity. It specifically binds to apo-IDO1, which lacks heme, instead of mature he... | |||
T39888 | IDO1-IN-7 | IDO1-IN-7 | |
IDO1-IN-7, a potent and selective indoleamine-2,3-dioxygenase-1 (IDO1) inhibitor, exhibits high potency with an IC 50 of 6.1 nM in the cellular assay (SKOV3). Apart from its inhibitory properties, IDO1-IN-7 also demonstr... | |||
T39946 | IDO1-IN-12 | IDO1-IN-12 | |
IDO1-IN-12 is a potent and orally available IDO1 inhibitor. | |||
T39839 | IDO1-IN-11 | IDO1-IN-11 | |
IDO1-IN-11 is an IDO1 inhibitor with an IC 50 value of 0.6 nM. | |||
T7504 | Necrostatin 2 racemate | Necrostatin-2 racemate | RIP kinase |
Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1. | |||
T37329 | PROTAC IDO1 Degrader-1 | PROTAC IDO1 Degrader-1 | |
PROTAC IDO1 Degrader-1, a pioneering compound, efficiently targets indoleamine 2,3-dioxygenase 1 (IDO1) for ubiquitination and degradation by recruiting IDO1 to the CRBN E3 ligase, thereby facilitating its entry into the... | |||
T5314 | Pyridoxal isonicotinoyl hydrazone | PIH | Others |
pyridoxal isonicotinoyl hydrazone (PIH) is a cell-permeable and relatively non-toxic iron (Fe3+) chelator that shows high iron chelation efficacy both in vitro and in vivo. | |||
T22520 | 5-Carboxamidotryptamine maleate | 5-CT maleate | 5-HT Receptor |
5-Carboxamidotryptamine maleate (5-CT maleate) (5-CT maleate) is a receptor agonist with antihypertensive and glucose-raising effects. | |||
T7525 | Didox | NSC-324360 | DNA/RNA Synthesis |
Didox (NSC-324360) is a synthetic ribonucleotide reductase (RR) inhibitor that has been found to reduce the levels of oxidative injury markers in the brains of HIV patients with dementia. | |||
T14871 | Carboxyamidotriazole Orotate | L-651582 Orotate,CAI Orotate | Calcium Channel |
Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole Orotate (L-651582 Orotate) is the o... | |||
T14038L | 4-Azido-L-phenylalanine hydrochloride | p-Azido-L-phenylalanine hydrochloride,p-Azidophenylalanine hydrochloride | Others |
4-Azido-L-phenylalanine hydrochloride (p-Azido-L-phenylalanine hydrochloride) is an unnatural amino acid used as an effective vibrational reporter of local protein environments. | |||
T17918 | Thalidomide-O-amido-PEG2-C2-NH2 TFA | E3 Ligase Ligand-Linker Conjugates 24 TFA,Cereblon Ligand-Linker Conjugates 10 TFA | Others , E3 Ligase Ligand-Linker Conjugate |
Thalidomide-O-amido-PEG2-C2-NH2 TFA (E3 Ligase Ligand-Linker Conjugates 24 TFA) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-PEG2-C2-NH2 TFA incorporates the Thalidomide based cereblon ligand a... | |||
T17325 | Pomalidomide-PEG4-C-COOH | Cereblon Ligand -Linker Conjugates 1,E3 Ligase Ligand-Linker Conjugates 1 | Others , E3 Ligase Ligand-Linker Conjugate |
Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology. | |||
T77912 | Tz-Thalidomide | Epigenetic Reader Domain | |
Tz-Thalidomide is a tetrazine-modified Thalidomide (E3 ligase ligand) with some affinity for BRD4. | |||
T22338 | 2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide | GDC046 | Others , JAK |
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity, physicochemical properties and pharmacokinetic profile. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T4S0051 | Coptisine sulfate | Indoleamine 2,3-Dioxygenase (IDO) | |
1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program. | |||
T5S0053 | Coptisine | Coptisin | Indoleamine 2,3-Dioxygenase (IDO) |
1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ... | |||
T3S1967 | (S)-Indoximod | N-ME-Tryptophan,Abrine,L-Abrine | Others , Indoleamine 2,3-Dioxygenase (IDO) |
(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L... | |||
T2718 | Palmatine chloride | Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase | |
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties. | |||
T5S0802 | Palmatine | Berbericinine,Burasaine | Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase |
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,... | |||
T5S0056 | Coptisine chloride | Q-100696,NSC-119754 | Indoleamine 2,3-Dioxygenase (IDO) , Influenza Virus , Antibacterial |
1. Coptisine chloride (NSC-119754) can be absorbed across intestinal epithelial cells, and completely absorbed compounds. | |||
T8214 | Kushenol E | Flemiphilippinin D | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
Kushenol E (Flemiphilippinin D) is a class of flavonoids isolated from Sophora flavescens. It is a non-competitive IDO1 inhibitor (IC50: 7.7 μM, Ki: 9.5 μM), has anti-tumor activity. | |||
T5085 | Pyridoxal 5'-phosphate hydrate | Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),PLP,Pyridoxal 5'-phosphate hydrate | Others , Endogenous Metabolite |
Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions, including mitochondrial cysteine desulfurase, cystathionine γ-synth... | |||
TN1035 | Irisolidone | IL Receptor , NF-κB , Chloride channel | |
Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM. | |||
TN7032 | 4'-O-Methylpyridoxine | 4-methoxymethylpyridoxine,Ginkgotoxin | Antioxidant |
4'-O-Methylpyridoxine (MPN) is a vitamin-like compound discovered from Ginkgo biloba with antioxidant activity and cytotoxicity. | |||
T2790 | Oridonin | NSC-250682,Rubescenin,Isodonol,Rubescensin A | Akt , Antibacterial |
Oridonin (NSC-250682) is a diterpenoid isolated from Rabdosia rubescens with anti-tumor, anti-bacterial and anti-inflammatory effects. It acts as an inhibitor of AKT, with IC50s of 8.4 and 8.9 μM for AKT1 and AKT2. | |||
T4933 | (S)-2-acetamido-4-amino-4-oxobutanoic acid | Nα-Acetyl-L-asparagine | Endogenous Metabolite |
(S)-2-acetamido-4-amino-4-oxobutanoic acid (Nα-Acetyl-L-asparagine), also known as acasn, is an endogenous metabolite. | |||
T4919 | Ureidopropionic acid | Carbamoyl-b-alanine,3-Ureidopropionic acid | Endogenous Metabolite |
Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. It is further de... | |||
T8083 | Pyridoxal 5'-phosphate monohydrate | Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate | Others |
Pyridoxal 5'-phosphate monohydrate is an active vitamin B6 metabolite | |||
T20003 | Acridone | Antibacterial , ABC | |
Acridone could induce cell apoptosis, inhibited ABCG2 (ATP-binding cassette sub-family G member 2) protein, and adjusted hormone level. | |||
T4761 | Pyridoxal hydrochloride | Others , Endogenous Metabolite | |
The 4-carboxyaldehyde form of vitamin B6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. | |||
TN1819 | Kaempferol 3-neohesperidoside | Kaempferol 3-O-neohesperidoside | GSK-3 , MEK , PI3K |
Kaempferol 3-neohesperidoside (Kaempferol 3-O-neohesperidoside), a flavonoid compound, demonstrates an insulinomimetic effect on the rat soleus muscle. | |||
T7324 | Chelidonine hydrochloride | Others | |
Chelidonine hydrochloride is one of the alkaloids of Chelidonium majus, which has broad pharmacological activities | |||
T19962 | Xyloidone | NSC-106453,NSC106453,Dehydro-α-lapachone,NSC 106453,Dehydrolapachone,NSC 629748 | Antifungal |
Xyloidone (NSC-106453) exhibits antifungal activity and completely inhibits the mycelial growth of B. cinerea, Colletotrichum acutatum Simmonds, Colletotrichum gloeosporioides Simmonds, M. grisea, and Pythium ultimum Tro... | |||
T2931 | 2-Amino-5-ureidopentanoic acid | DL-Citrulline,Citrulline | Others , Endogenous Metabolite |
2-Amino-5-ureidopentanoic acid (Citrulline) exists in the liver, is not a protein component, is an important intermediate in the human urea cycle, can be combined with ornithine, arginine to treat hyperammonemia. | |||
T36473 | Trans-Nerolidol | Antifungal | |
trans-Nerolidol is a sesquiterpene alcohol isolated from the above-ground parts of the Saharan Valerian plant with antifungal activity. trans-Nerolidol inhibits cell proliferation in a dose-dependent manner, and induces ... | |||
T9279 | Nerolidol acetate | Others | |
Nerolidol acetate is a natural sesquiterpene with anti-cancer, anti-inflammatory, antibacterial and anti-insect activities. Nerolidol acetate can inhibit parasite activity and inhibit schistosomiasis, nematodes, malaria,... | |||
T12588 | Pyridoxylamine | pyridoxamine | Endogenous Metabolite |
Pyridoxylamine (pyridoxamine) is an inhibitor of advanced glycation end production (AGEs) and lipoxidation end products (ALEs). | |||
T0973 | Pyridoxine | Pyridoxol,Vitamin B6,Gravidox | PLK , Nrf2 , Endogenous Metabolite |
Pyridoxine (Vitamin B6) is the 4-methanol form of vitamin B6 and is converted to pyridoxal 5-phosphate in the body. Although pyridoxine and vitamin B6 are still frequently used as synonyms, especially by medical research... | |||
T6795 | Carbidopa | (S)-(-)-Carbidopa,Lodosyn | Decarboxylase , Aryl Hydrocarbon Receptor |
Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM). It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA. | |||
T0973L | Pyridoxine hydrochloride | Pyridoxine HCl,Pyridoxol (hydrochloride),Vitamin B6 (hydrochloride),Vitamin B6 | Nrf2 , Endogenous Metabolite |
Pyridoxine hydrochloride (Vitamin B6) is the 4-methanol form of vitaminB6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingo... | |||
T4728 | 4-Acetamidobutanoic acid | N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID | GABA Receptor , Endogenous Metabolite , Antibacterial |
4-Acetamidobutanoic acid (4-ACETAMIDOBUTYRIC ACID) can be found in blood, feces, and urine, as well as in human prostate tissue. 4-Acetamidobutanoic acid exists in all eukaryotes, ranging from yeast to humans. 4-Acetamid... | |||
T4129 | Arachidonic acid | Immunocytophyte,arachidonate,Immunocytophyt,Vevodar | Others , Endogenous Metabolite |
Arachidonic acid (Immunocytophyte) is an unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is for... | |||
T3578 | Pyridoxal phosphate | PLP,PAL-P,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate | Reverse Transcriptase , Endogenous Metabolite |
Pyridoxal phosphate (Vitamin B6 phosphate) is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and d... | |||
T5558 | Chelidonic acid | Jervaic acid,Jerva acid,γ-Pyrone-2,6-dicarboxylic acid | NF-κB , Caspase |
Chelidonic acid (Jervaic acid) is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid (Jervaic acid) also shows anti-inflammatory activity... | |||
T3799 | Isorhamnetin-3-O-neohespeidoside | Isorhamnetin 3-O-neohesperidin,Isorhamnetin 3-O-neohesperoside,Calendoflavoside | Antioxidant |
Isorhamnetin-3-O-neohespeidoside (Calendoflavoside) is a flavonol glycoside extract used as an anti-oxidant. | |||
T0436 | 6-Acetamidohexanoic acid | 6-Acetamidocaproic acid,Acexamic Acid | Amino Acids and Derivatives , COX |
6-Acetamidohexanoic acid (Acexamic Acid) is a kind of amino acids deriviate. | |||
T25114 | Ascaridole | NSC-406266,NSC 406266,NSC406266 | Parasite |
Ascaridole (NSC-406266) acts as an anthelmintic compound that repels parasitic helminths (worms) in humans and plants and has weak antimalarial activity. | |||
T0076 | Paliperidone | 9-hydroxyrisperidone | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor |
Paliperidone (9-hydroxyrisperidone)(Invega) is used as an atypical antipsychotic. It applies to the acute and maintenance treatment of schizophrenia. Chemically, paliperidone is the primary active metabolite of the older... | |||
T5S0055 | Chelidonine | Helidonine,Khelidonin,Stylophorin | Apoptosis , Others , Influenza Virus |
1. Chelidonine (Stylophorin) isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelidonine is a promising model ... | |||
T4107 | 4-Pyridoxic Acid | Pyridoxic Acid,4-Pyridoxinsaeure | Endogenous Metabolite |
4-Pyridoxic Acid (4-Pyridoxinsaeure), a catabolite of vitamin B6, is a water-soluble B-group vitamin that can be used as a urinary diagnostic biomarker for determining the nutritional status of these vitamins. | |||
T4754 | Pyridoxylamine dihydrochloride | Pyridorin,Pyridoxamine dihydrochloride | Others , Endogenous Metabolite |
Pyridoxylamine dihydrochloride (Pyridorin) is a hydrochloride salt of one form of vitamin B6. | |||
T2S2172 | Nerolidol | (±)-Nerolidol,Peruviol | Others , Endogenous Metabolite , Antibacterial , Parasite , Antifungal |
Nerolidol (Peruviol) shows sedative effects in animals, oxidative process plays a crucial role on neuronal pathological consequence. Nerolidol is mainly related to ROS and DNA single strand breaks generated by the presen... | |||
T5217 | 2-(2-Phenylacetamido)acetic acid | Phenaceturic acid,Phenyl-ac-Gly-OH,Phenylacetyl glycine | Others , Endogenous Metabolite |
2-(2-Phenylacetamido)acetic acid (Phenyl-ac-Gly-OH) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. The presence of phenylacetylglycine in urine has been confirmed for dogs, rats, and mic... | |||
T5226 | 2-(2-Methylbenzamido)acetic acid | 2-Methylhippuric acid,O-Toluric acid,N-(O-Toluoyl)glycine | Others , Endogenous Metabolite |
2-(2-Methylbenzamido)acetic acid (O-Toluric acid) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. In certain cases, the measurement of these metabolites in body fluids can be used to diag... | |||
T4805 | α-Pyridone | 2-Hydroxypyridine | Others , Endogenous Metabolite |
α-Pyridone (2-Hydroxypyridine)e is the catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate. | |||
T7916 | 4-Acetamidobenzenesulfonyl azide | Others | |
4-Acetamidobenzenesulfonyl azide is used in a variety of scientific research applications, including the synthesis of drugs, peptides and other biologically active molecules. It is also used as a catalyst in polymerizati... | |||
TN3632 | (-)-Chelidonine | Others | |
(-)-Chelidonine is a natural product from Glaucium squamigerum KAR. et KIR. | |||
TN4141 | Glochidone | Others | |
Glochidone shows pronounced antinociceptive properties in mice. | |||
T15703 | Lactimidomycin | Others | |
Lactimidomycin, isolated from Streptomyces, is an inhibitor of eukaryotic translation elongation. It is also a potent and non-toxic inhibitor of dengue virus 2 and other RNA viruses. Lactimidomycin has an antiproliferati... | |||
T83272 | 6′-O-β-D-Glucopyranosylphlorigidoside C | ||
Compound 1, known as 6′-O-β-D-Glucopyranosylphlorigidoside C, is an iridoid glycoside extractable from the plant Lamiophlomis rotata [1]. | |||
TN4022 | Ethyllucidone | Others | |
Ethyllucidone is a natural product for research related to life sciences. The catalog number is TN4022 and the CAS number is 1195233-59-0. | |||
TN4142 | Glochidonol | Others | |
Glochidonol exhibits strong inhibitory effects against three human tumor cell lines, MCF-7, NCI-H-460 and SF-268, the GI(50) values of 9.0 +/- 3.7, 4.9 +/- 0.2 and 9.8 +/- 0.5, respectively; it also exerts its antiprolif... | |||
TN3845 | Diethyl 2-acetamido-2-(4-octylphenethyl)malonate | Others | |
Diethyl 2-acetamido-2-(4-octylphenethyl)malonate is a natural product for research related to life sciences. The catalog number is TN3845 and the CAS number is 162358-08-9. | |||
TN4928 | Rutacridone | P450 | |
Rutacridone has mutagenicity. | |||
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カタログ番号 | 製品名 | Species | Expression System |
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TMPY-02928 | IDO Protein, Human, Recombinant | Human | E. coli |
IDO Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 45.2 kDa and the accession number is A0A348GSI3. | |||
TMPY-01821 | IDO Protein, Human, Recombinant (His) | Human | E. coli |
IDO Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46 kDa and the accession number is P14902-1. | |||
TMPY-06772 | IDO Protein, Mouse, Recombinant (His) | Mouse | E. coli |
IDO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.47 kDa and the accession number is P28776. | |||
TMPY-02803 | IDO2 Protein, Human, Recombinant (His) | Human | E. coli |
IDO2 belongs to the indoleamine 2,3-dioxygenase family. Indoleamine 2,3-dioxgyenase (IDO), is a cytosolic haem protein which, together with the hepatic enzyme tryptophan 2,3-dioxygenase, catalyzes the conversion of trypt... | |||
TMPH-00089 | SPT16 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) | Arabidopsis thaliana | E. coli |
SPT16 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.9 kDa and the accession number is O82491. | |||
TMPH-00077 | IAA17 Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | E. coli |
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response fac... | |||
TMPH-00113 | UGT78D1 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | E. coli |
Flavonol 3-O-rhamnosyltransferase that catalyzes the transfer of rhamnose from UDP-rhamnose to the 3-OH position of kaempferol and quercetin. Possesses low quercetin 3-O-glucosyltransferase activity in vitro. UGT78D1 Pro... | |||
TMPY-00292 | Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP (Virion spike glycoprotein) Protein (His) | EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP (Virion spike glycoprotein) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight... | |||
TMPH-00111 | UGT72E2 Protein, Arabidopsis thaliana, Recombinant (E. coli, His & Myc) | Arabidopsis thaliana | E. coli |
Involved in the O-glucosylation of monolignols (alcohol monomers of lignin). Glucosylates coniferyl alcohol to form coniferyl alcohol 4-O-glucoside. Glucosylates sinapyl alcohol to form sinapyl alcohol 4-O-glucoside. Glu... | |||
TMPH-00104 | NLP7 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | Baculovirus Insect Cells |
Transcription factor involved in regulation of nitrate assimilation and in transduction of the nitrate signal. NLP7 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis ... | |||
TMPH-00082 | DREB2C Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | E. coli |
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and abscisic acid-inducible transcription. DREB2C Protein, Arabidopsis th... | |||
TMPH-00075 | At1g09870/F21M12_26 Protein, Arabidopsis thaliana, Recombinant (E. coli, His) | Arabidopsis thaliana | E. coli |
At1g09870/F21M12_26 Protein, Arabidopsis thaliana, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 58.8 kDa and the accession number is Q941B2. | |||
TMPY-00064 | Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Matrix protein VP40 Protein (His) | EBOV | E. coli |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.1 kDa and the ... | |||
TMPH-00107 | UBC10 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | E. coli |
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. UBC10 Protein, Arabidopsis thaliana, Recombinant... | |||
TMPH-00081 | CDKB1-2 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | P. pastoris (Yeast) |
Together with CDKB1-1, promotes both the last division in the stomatal cell lineage as well as the number of stomata. In collaboration with MYB124 and MYB88, restrict the G1/S transition and chloroplast and nuclear numbe... | |||
TMPH-00100 | OSM34 Protein, Arabidopsis thaliana, Recombinant (His & Myc & SUMO) | Arabidopsis thaliana | E. coli |
OSM34 Protein, Arabidopsis thaliana, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 44.4 kDa and the accession number is P5070... | |||
TMPY-01502 | Influenza A H5N3 (A/duck/Hokkaido/167/2007) Hemagglutinin/HA Protein (His) | H5N3 | HEK293 Cells |
Influenza A H5N3 (A/duck/Hokkaido/167/2007) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is B1AHS0. | |||
TMPH-00102 | RBP47A Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | E. coli |
Heterogeneous nuclear ribonucleoprotein (hnRNP)-protein binding the poly(A) tail of mRNA and probably involved in some steps of pre-mRNA maturation. RBP47A Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expres... | |||
TMPH-00109 | UBC8 Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | E. coli |
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. UBC8 Protein, Arabidopsis thaliana, Recombinant ... | |||
TMPY-00098 | Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (Fc) | EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 57.6 kDa and the acces... | |||
TMPH-00076 | At1g09870/F21M12_26 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His) | Arabidopsis thaliana | Baculovirus Insect Cells |
At1g09870/F21M12_26 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 55.2 kDa and the accession number is Q941B2. | |||
TMPH-00087 | Expansin-A1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | E. coli |
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. Expansin-A1 Protein, Arabidopsis thaliana, Re... | |||
TMPH-00080 | Catalase-2 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) | Arabidopsis thaliana | E. coli |
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase-2 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) is expressed in E. coli exp... | |||
TMPH-00101 | PDLP7 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) | Arabidopsis thaliana | E. coli |
Modulates cell-to-cell trafficking. PDLP7 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.3 kDa and the access... | |||
TMPH-00085 | SIZ1 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | E. coli |
E3 SUMO protein ligase involved in regulation processes. Mediates SUMO/ attachment to PHR1, a MYB transcriptional activator controlling the phosphate deficiency responses. Functions as an upstream negative regulator of s... | |||
TMPH-00091 | UGT71C1 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His) | Arabidopsis thaliana | P. pastoris (Yeast) |
Possesses quercetin 7-O-glucosyltransferase and 3'-O-glucosyltransferase activities in vitro. Also active in vitro on benzoates and benzoate derivatives. Glucosylates other secondary metabolites in vitro like trans-resve... | |||
TMPH-00090 | UGT71C1 Protein, Arabidopsis thaliana, Recombinant (E. coli, His) | Arabidopsis thaliana | E. coli |
Possesses quercetin 7-O-glucosyltransferase and 3'-O-glucosyltransferase activities in vitro. Also active in vitro on benzoates and benzoate derivatives. Glucosylates other secondary metabolites in vitro like trans-resve... | |||
TMPH-00105 | RGF1 Protein, Arabidopsis thaliana, Recombinant (GST) | Arabidopsis thaliana | E. coli |
RGF1 Protein, Arabidopsis thaliana, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 28.2 kDa and the accession number is Q3E880. | |||
TMPH-00112 | UGT72E2 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His & Myc) | Arabidopsis thaliana | Baculovirus Insect Cells |
Involved in the O-glucosylation of monolignols (alcohol monomers of lignin). Glucosylates coniferyl alcohol to form coniferyl alcohol 4-O-glucoside. Glucosylates sinapyl alcohol to form sinapyl alcohol 4-O-glucoside. Glu... | |||
TMPY-00240 | Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP1/Glycoprotein Protein (His) | EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP1/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.3 kDa and the access... | |||
TMPH-02812 | Nidogen-1 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions. | |||
TMPH-00086 | EPFL9 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | E. coli |
Positively regulates stomatal density and patterning. Acts by competing with EPF2 (AC Q8LC53) for the same receptors, ERECTA (AC Q42371) and TMM (AC Q9SSD1). Not cleaved by the protease CRSP (AC Q9LNU1). EPFL9 Protein, A... | |||
TMPH-00103 | Probable sarcosine oxidase Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | E. coli |
N/A. Probable sarcosine oxidase Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 49.7 kDa and the accession number is Q9SJA7. | |||
TMPH-00094 | HSP21, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | E. coli |
Chaperone protein required for seedling and chloroplast development under heat stress, probably by maintaining plastid-encoded RNA polymerase (PEP)-dependent transcription. HSP21, chloroplastic Protein, Arabidopsis thali... | |||
TMPH-00099 | NDK1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | P. pastoris (Yeast) |
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Plays a... | |||
TMPY-00255 | Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP2/Glycoprotein Protein (Fc) | EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP2/Glycoprotein Protein (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 43.4 kDa and the accessio... | |||
TMPH-00095 | HDT2 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | P. pastoris (Yeast) |
Probably mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcr... | |||
TMPH-00078 | Beta-amylase 1, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | E. coli |
Beta-amylase activity. Can use p-nitrophenyl maltopentaoside (PNPG5) as substrate only in reduced form. Can play a minor role in the starch degradation and maltose metabolism in chloroplasts during the night. More active... | |||
TMPH-00084 | Dehydrin Xero 2 Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | E. coli |
Dehydrin Xero 2 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.4 kDa and the accession number is P42758. | |||
TMPY-00245 | Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Makona-Kissidougou-C15) GP/Glycoprotein Protein (His) | EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Makona-Kissidougou-C15) GP/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 kDa and the ... | |||
TMPH-00114 | UGT88A1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | Baculovirus Insect Cells |
Possesses low quercetin 3-O-glucosyltransferase, 7-O-glucosyltransferase, 3'-O-glucosyltransferase and 4'-O-glucosyltransferase activities in vitro. UGT88A1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expre... | |||
TMPY-00041 | Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP1 Protein (His) | EBOV | Baculovirus Insect Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP1 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 52.3 kDa and the acce... | |||
TMPH-03075 | 3FTx-Oxy6 Protein, Oxyuranus microlepidotus, Recombinant (His & Myc & SUMO) | Oxyuranus microlepidotus | E. coli |
3FTx-Oxy6 Protein, Oxyuranus microlepidotus, Recombinant (His & Myc & SUMO) is expressed in E. coli. | |||
TMPH-00071 | AtHsp23.6 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | E. coli |
AtHsp23.6 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.4 kDa and the accession number is Q96331. | |||
TMPH-03608 | Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His) | Streptomyces viridochromogenes | P. pastoris (Yeast) |
Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Phosphinothricin N-acetyltransferase Protein, S.... | |||
TMPH-00116 | UGT89C1 Protein, Arabidopsis thaliana, Recombinant (Yeast, His) | Arabidopsis thaliana | P. pastoris (Yeast) |
UGT89C1 Protein, Arabidopsis thaliana, Recombinant (Yeast, His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 50.6 kDa and the accession number is Q9LNE6. | |||
TMPH-00088 | Expansin-B1 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | E. coli |
May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. | |||
TMPY-00102 | Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (His) | EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the acc... | |||
TMPH-00074 | GlcNAcT-I Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | Baculovirus Insect Cells |
Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. Required for normal root growth and morphology. GlcNAcT-I Protein, Arabidopsis thaliana, R... | |||
TMPY-01503 | Influenza A H5N3 (A/duck/Hokkaido/167/2007) Hemagglutinin/HA1 Protein (His) | H5N3 | HEK293 Cells |
Influenza A H5N3 (A/duck/Hokkaido/167/2007) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is B1AHS0. | |||
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