Powder: -20°C for 3 years | In solvent: -80°C for 1 year
IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α and IL-6 production in vitro.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 8,000 | |||
5 mg | 在庫あり | ¥ 18,000 | |||
10 mg | 在庫あり | ¥ 27,000 | |||
25 mg | 在庫あり | ¥ 53,000 | |||
50 mg | 在庫あり | ¥ 85,000 | |||
100 mg | 在庫あり | ¥ 126,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 20,500 |
説明 | IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α and IL-6 production in vitro. |
ターゲット&IC50 | JNK3:66 nM(Kd) , JNK1:240 nM(Kd) , JNK2:290 nM(Kd) |
分子量 | 341.32 |
分子式 | C20H11N3O3 |
CAS No. | 312538-03-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.41 mg/mL (10 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
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