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ターゲット

Angiotensin-converting Enzyme (ACE) RAAS Endogenous Metabolite

366

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天然化合物

リコンビナントタンパク質

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カタログ番号	製品名	別名	ターゲット
T7339	Angiotensin (1-7)	Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO	RAAS , Endogenous Metabolite
	Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) is a synthetic heptapeptide identical to endogenous angiotensin-(1-7) , inhibits purified canine ACE activity (IC50=0.65 μM) with vasodilator and antiproliferative activiti...		RAAS , Endogenous Metabolite
TP1528	Angiotensin I/II (1-5)	Angiotensin I/II 1-5	RAAS , Others
	Angiotensin I/II (1-5) is a peptide (ASP-ARG-VAL-TYR-ILE) that contains the amino acids 1-5 and is converted from Angiotensin I/II.		RAAS , Others
TP1579	Angiotensin I/II (1-6)	Angiotensin I/II 1-6	RAAS , Others
	Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) that contains the amino acids 1-6 and is converted from Angiotensin I/II peptide.		RAAS , Others
T7577	Angiotensin III, human, mouse	Angiotensin III, human, mouse(3TFA)	RAAS
	Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA))(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).		RAAS
TP1295	Angiotensin I (human, mouse, rat)	Angiotensin 1 Human	Others
	Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE).Angiotensin is a peptide hormone that causes vasoconstriction and an in...		Others
T7575L	[Sar1, Ile8]-Angiotensin II 3TFA	[Sar1, Ile8]-Angiotensin II 3TFA(37827-06-8(free base))	Others
	[Sar1, Ile8]-Angiotensin II 3TFA ([Sar1, Ile8]-Angiotensin II 3TFA (37827-06-8(free base))) is a peptide that has multiple effects on vascular smooth muscle.		Others
T8560	Angiotensin II human acetate	Ang II acetate,DRVYIHPF acetate,Angiotensin II acetate	Apoptosis , RAAS
	Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.		Apoptosis , RAAS
TP2446L	Angiotensin amide acetate	Angiotensin amide acetate(53-73-6 Free base)	Others
	Angiotensin amide acetate is a derivative of Angiotensin amide, an octapeptide amide that increases blood pressure through vasoconstriction.		Others
TP1017L	Angiotensin II 5-valine TFA	Angiotensin II 5-valine TFA(58-49-1 free base)	RAAS
	Angiotensin II 5-valine TFA is an agonist of angiotensin receptor.		RAAS
T21708L	Angiotensin 1/2 + A (2 - 8) Acetate	Angiotensin 1/2 + A (2 - 8) Acetate (51833-76-2 Free base)	Others
	Angiotensin 1/2 + A (2 - 8) Acetate is a Vasoconstrictor.		Others
T35834L	(Sar¹)-Angiotensin II acetate		RAAS
	(Sar¹)-Angiotensin II acetate, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. It binds to brain membrane-rich particles, with a Kd of 2.7 nM. It can stimulate protein synthesis and cell...		RAAS
T7575L1	[Sar1, Ile8]-Angiotensin II acetate		RAAS
	[Sar1, Ile8]-Angiotensin II acetate activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells. [Sar1, Ile8]-Angiotensin II acetate has multiple effects on vascu...		RAAS
T22574L	Angiotensin 1/2 (5-7) acetate		RAAS
	Angiotensin 1/2 (5-7) acetate is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum...		RAAS
T7743	ANGIOTENSIN IV TFA(12676-15-2(free base))		RAAS
	ANGIOTENSIN IV TFA is a less effective agonist at the angiotensin AT1 receptor.		RAAS
T7663L	Angiotensin 1/2 (1-9) TFA(34273-12-6(free base))		Others
	Angiotensin 1/2 (1-9)TFA is containing the amino acids 1-9 that are converted from Angiotensin I/II peptide.		Others
T35834	(Sar1)-Angiotensin II	(Sar¹)-Angiotensin II
	The substitution with Sar at position 1 of angiotensin II resulted in a partial agonistic activity.
TP2370	Angiotensin pentapeptide	Angiotensin II (4-8),(Des-1,2,3)angiotensin II
	Angiotensin pentapeptide is a peptide.
T5824	Angiotensin II (3-8), human	Angiotensin IV	RAAS
	Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.		RAAS
T7575	[Sar1, Ile8]-Angiotensin II	[Sar1, Ile8]-Angiotensin II(3TFA)	RAAS , Others
	[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.		RAAS , Others
TP1017	Angiotensin II 5-valine	Valine angiotensin II,5-L-Valine angiotensin II
	ngiotensin II 5-valine is an angiotensin II analog which is an agonist at angiotensin receptors.
TP2446	Angiotensin amide	Angiotensinamide,Hypertensine,Angiotensin,NSC 107678,NSC-107678
	Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.
TP1224	[Sar1, Ile8]-Angiotensin II TFA	Angiotensin 2 TFA,AngiotensinII TFA
	[Sar1, Ile8]-Angiotensin II (TFA) is a peptide compound that exerts various effects on vascular smooth muscle. These effects include the contraction of normal arteries as well as the hypertrophy or hyperplasia of culture...
T31096	Crinia-angiotensin
	Crinia-angiotensin is an Angiotensin II-like undecapeptide from the skin of Australian frog Crinia georgiana.
T10322L	Angiotensin III TFA (12687-51-3 free base)	Angiotensin III TFA	Others
	Angiotensin III TFA is an agonist of angiotensin 1 (AT1) and AT2 receptor.		Others
T10322	Angiotensin III		Others
	Angiotensin III is an agonist of angiotensin 1 (AT1) and AT2 receptor.		Others
T37495	Angiotensin (1-7) (acetate)
	Angiotensin 1-7 (Ang-(1-7)) acetate, an endogenous heptapeptide from the renin-angiotensin system (RAS), exhibits cardioprotective effects through its anti-inflammatory and anti-fibrotic activities in cardiac cells. It e...
T38697	[Tyr(P)4] Angiotensin II
	[Tyr(P)4] Angiotensin II is a peptide that exerts a multitude of effects on vascular smooth muscle. These effects include the contraction of normal arteries, as well as the induction of hypertrophy or hyperplasia in cult...
T36622	Angiotensin I/II (1-6) (TFA)
	Angiotensin I/II (1-6) TFA is a chemical compound comprising amino acids 1-6. It is derived from the Angiotensin I/II peptide, which is formed by the cleavage of the precursor angiotensinogen by renin. The resulting Angi...
TP2464	Pentasarcosyl angiotensin II	(Sar)5 aii
	Pentasarcosyl angiotensin II is a synthetic analog of angiotensin II.
T7663	Angiotensin 1/2 (1-9)		Others
	Angiotensin 1/2 (1-9) is containing the amino acids 1-9 that are converted from Angiotensin I/II peptide.		Others
TP1609	Angiotensin II (1-4), human
	Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure. Angiotensin also potentiates the release of norepinephrine by a direct action on po...
T22575	Angiotensin Fragment 1-7 (acetate)		Others
	Angiotensin Fragment 1-7 is a type 1 angiotensin II receptor agonist. In the renin-angiotensin system, angiotensin I is cleaved by the angiotensin-converting enzyme to form angiotensin II, which has effects on fluid and ...		Others
T22574	Angiotensin 1/2 (5-7)		Others
	Angiotensin 1/2 (5-7) is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globuli...		Others
T22573	Angiotensin 1/2 (2-7)		Others
	Angiotensin I/II (2-7) is a peptide that contains the amino acids 2-7 and is converted from Angiotensin I/II peptide. Angiotensin is a peptide hormone that causes vasoconstriction and a subsequent increase in blood press...		Others
TP1522	Angiotensin II (5-8), human
	Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II
TP2220	Angiotensin 1/2 (1-8) amide		Others
	Angiotensin 1/2 (1-8) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide) is a peptide analog to angiotensin II that is used as a vasopressor agent in the treatment of certain types of shock and circulatory collapse. It is...		Others
T22572	Angiotensin 1/2 (1-7) amide		Others
	Angiotensin I/II (1-7) amide is a peptide analog to angiotensin II that is used as a vasopressor in the treatment of certain types of shock and circulatory collapse. Angiotensin I/II amide is an amide derivative of angio...		Others
T10323	Angiotensin II (3-8), human TFA		RAAS
	Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.		RAAS
TP1661	Angiotensin II (1-4), human TFA
	Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.
TP2447	Angiotensin I, asn(1)-val(5)-gly(9)-
	Angiotensin I, asn(1)-val(5)-gly(9)- is isolated from the plasma of American eel, Anquilla rostrata.
T76169	Angiotensin-converting enzyme
	Angiotensin-converting enzyme (ACE), a dicarboxypeptidase, converts inactive Angiotensin I (Ang I) to its active form, Angiotensin II (Ang II), and degrades active bradykinin (BK), functioning as a potent vasoconstrictor...
T83483	[Val4] Angiotensin III
	[Val4] Angiotensin III is an angiotensin III peptide variant and a potent full agonist for Gαq and βarr2 signaling pathways, exhibiting pEC50 values of 8.31 and 8.44, respectively [1].
T74142	Angiotensin II human TFA
	Angiotensin II human TFA, a potent vasoconstrictor within the renin/angiotensin system, plays a pivotal role in human blood pressure regulation primarily through interactions with the G-protein-coupled receptors Angioten...
T76634	(Sar1,Ile4,8)-Angiotensin II
	(Sar1,Ile4,8)-Angiotensin II is a functionally selective agonist for the angiotensin II type 1 receptor (AT1R), enhancing insulin-stimulated signaling of the insulin receptor (IR) and glycogen synthesis. It boosts the in...
T75975	Angiotensin III, human, mouse TFA
	Angiotensin III, human, mouse (TFA) is an angiotensin.
TP1929L1	Saralasin acetate(34273-10-4 free base)		RAAS
	Saralasin acetate is a Non-selective angiotensin II antagonist.		RAAS
T7510	Leucylarginylproline		RAAS
	Leucylarginylproline is an inhibitor of angiotensin-converting enzyme (ACE) (IC50 : 0.27μM).		RAAS
T7714	Temocapil		Tyrosinase
	Temocapril is an inhibitor of tyrosine kinase.		Tyrosinase
T1484	Perindoprilat	Perindoprilate	RAAS , MRP , AChR
	Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.		RAAS , MRP , AChR
T2531	Eprosartan Mesylate	SKF-108566J	RAAS
	Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.		RAAS

Compounds

Angiotensin (1-7)

T7339

Synonym: Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO

Target: RAAS, Endogenous Metabolite

Angiotensin I/II (1-5)

TP1528

Synonym: Angiotensin I/II 1-5

Target: RAAS, Others

Angiotensin I/II (1-6)

TP1579

Synonym: Angiotensin I/II 1-6

Target: RAAS, Others

Angiotensin III, human, mouse

T7577

Synonym: Angiotensin III, human, mouse(3TFA)

Target: RAAS

Angiotensin I (human, mouse, rat)

TP1295

Synonym: Angiotensin 1 Human

Target: Others

[Sar1, Ile8]-Angiotensin II 3TFA

T7575L

Synonym: [Sar1, Ile8]-Angiotensin II 3TFA(37827-06-8(free base))

Target: Others

Angiotensin II human acetate

T8560

Synonym: Ang II acetate,DRVYIHPF acetate,Angiotensin II acetate

Target: Apoptosis, RAAS

Angiotensin amide acetate

TP2446L

Synonym: Angiotensin amide acetate(53-73-6 Free base)

Target: Others

Angiotensin II 5-valine TFA

TP1017L

Synonym: Angiotensin II 5-valine TFA(58-49-1 free base)

Target: RAAS

Angiotensin 1/2 + A (2 - 8) Acetate

T21708L

Synonym: Angiotensin 1/2 + A (2 - 8) Acetate (51833-76-2 Free base)

Target: Others

(Sar¹)-Angiotensin II acetate

T35834L

Synonym:

Target: RAAS

[Sar1, Ile8]-Angiotensin II acetate

T7575L1

Synonym:

Target: RAAS

Angiotensin 1/2 (5-7) acetate

T22574L

Synonym:

Target: RAAS

ANGIOTENSIN IV TFA(12676-15-2(free base))

T7743

Synonym:

Target: RAAS

Angiotensin 1/2 (1-9) TFA(34273-12-6(free base))

T7663L

Synonym:

Target: Others

(Sar1)-Angiotensin II

T35834

Synonym: (Sar¹)-Angiotensin II

Target:

Angiotensin pentapeptide

TP2370

Synonym: Angiotensin II (4-8),(Des-1,2,3)angiotensin II

Target:

Angiotensin II (3-8), human

T5824

Synonym: Angiotensin IV

Target: RAAS

[Sar1, Ile8]-Angiotensin II

T7575

Synonym: [Sar1, Ile8]-Angiotensin II(3TFA)

Target: RAAS, Others

Angiotensin II 5-valine

TP1017

Synonym: Valine angiotensin II,5-L-Valine angiotensin II

Target:

Angiotensin amide

TP2446

Synonym: Angiotensinamide,Hypertensine,Angiotensin,NSC 107678,NSC-107678

Target:

[Sar1, Ile8]-Angiotensin II TFA

TP1224

Synonym: Angiotensin 2 TFA,AngiotensinII TFA

Angiotensin III TFA (12687-51-3 free base)

T10322L

Synonym: Angiotensin III TFA

Angiotensin (1-7) (acetate)

T37495

Synonym:

Target:

[Tyr(P)4] Angiotensin II

T38697

Synonym:

Target:

Angiotensin I/II (1-6) (TFA)

T36622

Synonym:

Target:

Pentasarcosyl angiotensin II

TP2464

Synonym: (Sar)5 aii

Target:

Angiotensin 1/2 (1-9)

T7663

Synonym:

Target: Others

Angiotensin II (1-4), human

TP1609

Synonym:

Target:

Angiotensin Fragment 1-7 (acetate)

T22575

Synonym:

Target: Others

Angiotensin 1/2 (5-7)

T22574

Synonym:

Target: Others

Angiotensin 1/2 (2-7)

T22573

Synonym:

Target: Others

Angiotensin II (5-8), human

TP1522

Synonym:

Target:

Angiotensin 1/2 (1-8) amide

TP2220

Synonym:

Target: Others

Angiotensin 1/2 (1-7) amide

T22572

Synonym:

Target: Others

Angiotensin II (3-8), human TFA

T10323

Synonym:

Target: RAAS

Angiotensin II (1-4), human TFA

TP1661

Synonym:

Target:

Angiotensin I, asn(1)-val(5)-gly(9)-

TP2447

Synonym:

Target:

Angiotensin-converting enzyme

T76169

Synonym:

Target:

[Val4] Angiotensin III

T83483

Synonym:

Target:

Angiotensin II human TFA

T74142

Synonym:

Target:

(Sar1,Ile4,8)-Angiotensin II

T76634

Synonym:

Target:

Angiotensin III, human, mouse TFA

T75975

Synonym:

Target:

Saralasin acetate(34273-10-4 free base)

Synonym: Perindoprilate

Target: RAAS, MRP, AChR

カタログ番号	製品名	別名	ターゲット
T7040	Angiotensin II human	DRVYIHPF,Angiotensin II,Hypertensin II,Ang II	Apoptosis , RAAS
	Angiotensin II human (Ang II) is a biologically active peptide, a vasoconstrictor. Angiotensin II interacts with AT1R and AT2R to regulate blood pressure, stimulate sympathetic nerves, and increase aldosterone biosynthes...		Apoptosis , RAAS
T5S0106	Peimisine	Ebeiensine	RAAS , AChR
	1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe...		RAAS , AChR
T8270	Deserpidine	Harmonyl	RAAS
	Deserpidine (Harmonyl) is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive propertie...		RAAS
T13299	Vicenin 3		RAAS
	Vicenin 3 is an inhibitor of angiotensin-converting enzyme (ACE; IC50: 46.91 μM) from the aerial parts of Desmodium styracifolium.		RAAS
T5796	Plantainoside D	Isoplantamajoside	RAAS , PKC
	Plantainoside D (Isoplantamajoside) shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vitro with the IC(50) value of 2.17 mM, it ...		RAAS , PKC
T21418	Lisinopril	Linopril,Zestril,Prinivil,Lisipril	RAAS
	Lisinopril (Prinivil), the angiotensin-converting enzyme (ACE) inhibitor, is used primarily in the treatment of high heart failure, blood pressure, and heart attacks. It is also used for preventing eye and kidney complic...		RAAS
T3851	Vicenin 2	Vicenin -2	RAAS
	Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B, and RLAR. Vicenin 2 has hepatoprotective,...		RAAS
T3753	Sinapinic Acid	Sinapic acid,Synapoic acid	Apoptosis , RAAS , Reactive Oxygen Species , HDAC
	Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinap...		Apoptosis , RAAS , Reactive Oxygen Species , HDAC
T6627	Phosphoramidon Disodium	Phosphoramidon Disodium Salt	RAAS , Neprilysin , Others
	Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool.		RAAS , Neprilysin , Others
TN7109	Prosaikogenin G		RAAS
	Prosaikogenin G is a compound isolated from the roots of Buleurum bicaule Helm (Apiaceae) and id a derivative of Saikosaponin d in the gastrointestinal tract, exhibiting a significant inhibitory effect on angiotensin II...		RAAS
TN2295	Vicenin-1	Vicenin -1	Antioxidant , Angiotensin-converting Enzyme (ACE)
	Vicenin-1 (Vicenin -1) is a flavonoid glycoside isolated from the seeds of the leguminous plant fenugreek with potent anti-inflammatory and antioxidant activity, inhibiting angiotensin-converting enzyme (ACE).		Antioxidant , Angiotensin-converting Enzyme (ACE)
T6S0657	Isorhynchophylline	IsoRhy,Isorhyncophylline,Isorhychophylline,7-Isorhyncophylline	Others
	1. Isorhynchophylline (7-Isorhyncophylline) and rhyncophylline can directly inhibit the contractile responses induced by several agonists in small blood vessels of rat, they also can inhibit the hypertensive effect of an...		Others
TCS1704	Artemitin	Artemetin,Artemisetin,Erianthin	Antioxidant
	1. Artemitin (Erianthin) has anti-inflammatory activity. 2. Artemitin (Erianthin) protects endothelial function by acting as antioxidant and antiapoptotic agent and through the activation of ERK1/2 and Akt. 3. Intravenou...		Antioxidant
T0522	Diammonium Glycyrrhizinate	Glycyrrhizin	Dehydrogenase
	Diammonium Glycyrrhizinate (Glycyrrhizin) , an extensively used anti-inflammatory agent, is isolated from the licorice root. It is metabolized to glycyrrhetinic acid, which inhibits 11-β-hydroxysteroid dehydrogenase and ...		Dehydrogenase
T2836	Isorhamnetin	3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin	MEK , PI3K , Endogenous Metabolite
	Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LD...		MEK , PI3K , Endogenous Metabolite
T37298	Spinacine		Endogenous Metabolite
	Spinacine has been isolated from spinach and the roots of Panax ginseng. This conformationally constrained amino acid is a structural element in certain biologically active compounds as glucagon antagonists and angiotens...		Endogenous Metabolite
T38649	Lyciumin A
	Lyciumin A, a cyclic octapeptide, possesses inhibitory properties against proteases, renin, and angiotensin-converting enzyme. It holds potential for hypertension research.
T38481	Camellianin B
	Camellianin B, a flavonoid compound and metabolite of Camellianin A, exhibits antioxidant properties and acts as an angiotensin converting enzyme (ACE) inhibitor.
T19186	Aldosterone		Others
	Aldosterone is the primary mineralocorticoid. Aldosterone is synthesized and secreted in response to renin-angiotensin system activation or high dietary potassium by the zona glomerulosa of the adrenal cortex.		Others
T19911	Rescinnamine	Anaprel,Apoterin S,Apoterin
	Rescinnamine is an inhibitor of angiotensin-converting enzyme. It also is a vinca alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia. It used as an antihypertensive drug.
TN5645	Isomartynoside
	Isomartynoside has inhibition against the angiotensin converting enzyme (ACE) activities, the IC 50 value is 505±26.7μg/ml, it may have antihypertensive effect. Isomartynoside also shows obvious anti-fatigue activity.
TN2045	Pelargonidin-3-O-glucoside chloride		Others , Estrogen/progestogen Receptor
	Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. Pelargonidin-3-O-glucopyranoside has antioxidant, anti-inflammatory, anti-estrogenic, and angiotensin-converting enzyme ...		Others , Estrogen/progestogen Receptor
TN4103	Ganoderic acid K
	Ganoderic acid K is an angiotensin-converting enzyme inhibitor. It has anti-tumor, and anti-inflammatory activities.
T38593	1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone
	Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9, a quinolone alkaloid derived from Evodia rutaecarpa, is a potent antagonist of the angiotensin II receptor, displaying an IC50 value of 48.2 μM.
TN1060	Ganoderol A		Others
	Ganoderol A has significant anti-inflammatory activity and protection against UVA damage. it has an inhibitory effect on angiotensin converting enzyme activity and cholesterol biosynthesis.		Others
TN2487	1,3,5,6-Tetrahydroxyxanthone		Others
	1,3,5,6-Tetrahydroxyxanthone shows moderate hepatoprotective activity with EC(50) values of 160.2 +/- 0.6 microM against tacrine-induced cytotoxicity in HepG2 cells. It can inhibit angiotensin-I-converting-enzyme activit...		Others
TN4860	Pueroside B		COX , PPAR
	Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-converting enzyme (ACE), hydroxymethylglutaryl coenzyme A rece...		COX , PPAR
T81229	Safflor yellow B
	Safflor Yellow B mitigates angiotensin II-induced injury in human umbilical vein cells by modulating Bcl-2/p22(phox) expression and demonstrates neuroprotective effects [1].
TN1061	Ganoderol B		Androgen Receptor
	Ganoderol B is a potent β ±-glucosidase and angiotensin-converting enzyme inhibitor, with an IC(50) of β ±-glucosidase is 119.8 uM. It may be useful in prostate cancer and benign prostatic hyperplasia (BPH) therapy throu...		Androgen Receptor
TN4431	Leucosceptoside A		RAAS , PKC
	Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidase. Leucosceptoside A has antihypertensive effect, it shows ...		RAAS , PKC
T79958	Isocrenatoside		Angiotensin-converting Enzyme (ACE)
	Isocrenatoside (compound 6), a cyclic octapeptide derived from the ethanolic extract of Microtoena prainiana stems, functions as an angiotensin-converting enzyme (ACE) inhibitor. Research demonstrates that at a concentra...		Angiotensin-converting Enzyme (ACE)
T75697	1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone
	1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone, a diacylglycerol acyltransferase inhibitor and angiotensin II receptor blocker, exhibits IC50 values of 20.1 μM and 34.1 μM, respectively. Additionally, it demonstr...

天然物製品

Angiotensin II human

T7040

Synonym: DRVYIHPF,Angiotensin II,Hypertensin II,Ang II

Target: Apoptosis, RAAS

Synonym: Isoplantamajoside

Target: RAAS, PKC

Lisinopril

T21418

Synonym: Linopril,Zestril,Prinivil,Lisipril

Synonym: Sinapic acid,Synapoic acid

Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC

Phosphoramidon Disodium

T6627

Synonym: Phosphoramidon Disodium Salt

Target: RAAS, Neprilysin, Others

Target: Antioxidant, Angiotensin-converting Enzyme (ACE)

Isorhynchophylline

T6S0657

Synonym: IsoRhy,Isorhyncophylline,Isorhychophylline,7-Isorhyncophylline

Target: Others

Artemitin

TCS1704

Synonym: Artemetin,Artemisetin,Erianthin

Target: Antioxidant

Diammonium Glycyrrhizinate

T0522

Synonym: Glycyrrhizin

Target: Dehydrogenase

Isorhamnetin

T2836

Synonym: 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin

Target: MEK, PI3K, Endogenous Metabolite

Spinacine

T37298

Synonym:

Target: Endogenous Metabolite

Synonym: Anaprel,Apoterin S,Apoterin

Pelargonidin-3-O-glucoside chloride

TN2045

Synonym:

Target: Others, Estrogen/progestogen Receptor

1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone

1,3,5,6-Tetrahydroxyxanthone

Target: Androgen Receptor

Target: Angiotensin-converting Enzyme (ACE)

1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone

T75697

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-03830	ACE2/ACEH Protein, Rhesus, Recombinant (His)	Rhesus	HEK293 Cells
	ACE2/ACEH Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.1 kDa and the accession number is B6DUF3.
TMPY-03561	ACE2/ACEH Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293 Cells
	ACE2/ACEH Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110.7kDa and the accession number is B6DUF3.
TMPY-02207	ACE2/ACEH Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	ACE2/ACEH Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85 kDa and the accession number is Q5EGZ1.
TMPY-01838	ACE2/ACEH Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	ACE2/ACEH Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85 kDa and the accession number is Q8R0I0-1.
TMPH-02268	AGTR2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
TMPY-01839	ACE2/ACEH Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293 Cells
	ACE2/ACEH Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 112 kDa and the accession number is Q8R0I0-1.
TMPY-05266	ACE2/ACEH Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ACE2/ACEH Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.1 kDa and the accession number is Q9BYF1-1.
TMPY-00655	ACE2/ACEH Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ACE2/ACEH Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110.3 kDa and the accession number is Q9BYF1-1.
TMPY-05725	ACE2/ACEH Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Baculovirus Insect Cells
	ACE2/ACEH Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 86.86 kDa and the accession number is Q9BYF1-1.
TMPY-06334	ACE2/ACEH Protein, Human, Recombinant (hFc), Biotinylated	Human	HEK293 Cells
	ACE2/ACEH Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110.3 kDa and the accession number is NP_068576.1.
TMPY-05696	ACE2/ACEH Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	ACE2/ACEH Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.1 kDa and the accession number is Q9BYF1-1.
TMPY-04312	ACE2/ACEH Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	ACE2/ACEH Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 110 kDa and the accession number is Q9BYF1-1.
TMPJ-00386	ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated	Human	HEK293 Cells
	Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypept...
TMPH-03081	ACE2 Protein, Paguma larvata, Recombinant (hFc)	Paguma larvata	HEK293 Cells
	ACE2 Protein, Paguma larvata, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 112.7 kDa and the accession number is Q56NL1.
TMPH-02267	AGTRAP Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decr...
TMPY-04501	Angiotensinogen Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Angiotensinogen Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51 kDa and the accession number is A6KJ10.
TMPY-01232	Angiotensinogen Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Angiotensinogen Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.2 kDa and the accession number is B0ZBE2.
TMPY-02232	Angiotensinogen Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Angiotensinogen Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is P11859.
TMPK-00383	ACE2/ACEH Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio...
TMPY-02869	MMP-12 Protein, Human, Recombinant (catalytic domain)	Human	E. coli
	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPK-00382	ACE2/ACEH Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio...
TMPK-00551	ACE2/ACEH Protein, Cynomolgus, Recombinant (His & Avi)	Cynomolgus	HEK293 Cells
	ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio...
TMPK-00552	ACE2/ACEH Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated	Cynomolgus	HEK293 Cells
	ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio...
TMPY-02574	Chymase 1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	The STR polymorphism in the CMA1 gene is associated with asthma and that this association is even stronger with atopic asthma. CMA1 and IL-4 in atopic asthma and for IL-4 in atopy in general. The local angiotensin II sys...
TMPH-01041	Carboxypeptidase A6 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. Releases a C-terminal amino acid, with p...
TMPH-02778	Mcpt4 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-\|-Ile-5' bond of angiotensin I and the 'Phe-20-\|-Ala...
TMPH-03352	KLKB1 Protein, Rat, Recombinant (His)	Rat	P. pastoris (Yeast)
	The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role ...
TMPK-00913	SARS Spike S1 Protein (His & Avi), Biotinylated	SARS	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPK-00439	SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPK-00433	SARS-COV-2 Spike S1 Protein (hFc & Avi), Biotinylated	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPK-00434	SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPK-00908	SARS Spike S1 Protein (hFc & Avi)	SARS	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPK-00440	SARS-COV-2 Spike S1 Protein (His & Avi), Biotinylated	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPK-00437	SARS-COV-2 Spike RBD Protein (His & Avi)	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPK-00909	SARS Spike S1 Protein (hFc & Avi), Biotinylated	SARS	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPK-00912	SARS Spike RBD Protein (His & Avi), Biotinylated	SARS	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPK-00910	SARS Spike S1 Protein (His & Avi)	SARS	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPK-00432	SARS-COV-2 Spike S1 Protein (hFc & Avi)	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPH-03351	KLKB1 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role ...
TMPK-00438	SARS-COV-2 Spike S Trimer Protein (His & Avi)	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPK-00444	SARS-COV-2 Spike S1 NTD Protein (His & Flag)	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPK-00911	SARS Spike RBD Protein (His & Avi)	SARS	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPH-02881	Renin-2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Renin is a highly specific endopeptidase, related to pepsin, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood...
TMPK-00442	SARS-COV-2 (Omicron B.1.1.529) Spike S Trimer Protein (His & Avi), Biotinylated	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPK-00441	SARS-COV-2 Spike S Trimer Protein (His & Avi), Biotinylated	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPK-00443	SARS-COV-2 (Omicron B.1.1.529) Spike S1 Protein (His & Avi), Biotinylated	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays k...
TMPH-03106	Coagulation factor XII Protein, Pig, Recombinant (His)	Sus scrofa (Pig)	E. coli
	Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, whic...
TMPJ-00964	PRCP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, ...
TMPY-03269	Prolyl Endopeptidase Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Prolyl endopeptidase, also known as PREP, belongs to a distinct class of serine peptidases. It is a large cytosolic enzyme which was first described in the cytosol of rabbit brain as an oligopeptidase. Prolyl endopeptida...
TMPY-01027	Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. I...
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