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カタログ番号 | 製品名 | 別名 | ターゲット |
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T22344 | Icatibant Acetate | Bradykinin Receptor | |
Icatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema. | |||
T35664 | Tetracosactide acetate | Others | |
Cosyntropin (acetate) stimulates the release of corticosteroids such as cortisol from the adrenal gland. | |||
T20615 | Olsalazine | Dipentium,Salicylic acid | Others |
Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent. | |||
T9377 | ASK1-IN-2 | Apoptosis , ASK , MAPK | |
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can potentially be used as a therapeutic strategy for ulcerative colitis[1]. | |||
T22368 | Metyrosine | α-Methyltyrosine | COX |
Metyrosine (α-Methyltyrosine) is an antihypertensive drug and could be used as a tyrosine hydroxylase inhibitor.Metyrosine significantly inhibits high COX-2 activity. Metyrosine is a very effective agent for blood pressu... | |||
T4084 | Sibofimloc | VRT-1353385,Antibiotic-202,Antibiotic 202 | Antibacterial , Antibiotic |
Sibofimloc (Antibiotic-202), an antibiotic compound, is used in treating bacterial infections. | |||
T4602 | Hydrocortisone hemisuccinate | Hydrocortisone 21-he,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate | Glucocorticoid Receptor , Others , Interleukin |
Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent. | |||
T3147 | Pyrrolidinedithiocarbamate ammonium | PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate | NF-κB |
Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxide synthase mRNA to prevent induction. | |||
T35898 | Izencitinib | ||
Izencitinib (TD-1473) is an orally active, gut-restricted JAK inhibitor with non-selective properties. It is primarily employed in the investigation of ulcerative colitis [1]. | |||
T3620 | Solcitinib | GLPG-0778,GSK-2586184 | JAK |
Solcitinib (GLPG-0778) (GSK2586184, GLPG0778) is a JAK1 inhibitor. Solcitinib may be potentially used for the treatment of psoriasis, ulcerative colitis, and systemic lupus erythematosus. | |||
T1544 | Olsalazine disodium | Dipentum,Olsalazine Sodium | Others , COX , Antibacterial , Antibiotic |
Olsalazine disodium (Dipentum) is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis. | |||
T9914 | Vedolizumab | Integrin | |
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis. | |||
T70084 | Dersalazine | Dersalazine Free Base | IL Receptor , Platelet aggregation |
Dersalazine (Dersalazine Free Base), an inhibitor of platelet-activating factor, exerts intestinal anti-inflammatory activity in different rodent types of colitis by down-regulating IL-17 expression, with potential effic... | |||
T64334 | Glycolithocholic acid, sodium salt | Others | |
Glycolithocholic acid sodium salt, the sodium form of Glycolithocholic acid, is a glycine-conjugated secondary bile acid utilized in diagnosing ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH), and primary s... | |||
T10208 | A-69412 | N-1-(Fur-3-ylethyl)-N-hydroxyurea | Lipoxygenase |
A-69412 (N-1-(Fur-3-ylethyl)-N-hydroxyurea) is a reversible, specific inhibitor of the hydrophilic 5-lipoxygenase. It has the potential to treat ulcerative colitis and asthma, and possibly other inflammatory and allergic... | |||
T6923 | Ozanimod | RPC-1063 | S1P Receptor , LPL Receptor |
Ozanimod (RPC-1063) (RPC1063) is a specific oral S1P Receptor 1 modulator. Ozanimod has been used in trials studying the treatment of Crohn's Disease, Ulcerative Colitis, Multiple Sclerosis, and Relapsing Multiple Sclero... | |||
T77666 | MoTPS1-IN-1 | Antifungal | |
MoTPS1-IN-1 is a potent MoTPS1 inhibitor with antifungal and potentially anti-inflammatory activity that acts through interaction with Glu396 and can be used to study ulcerative colitis. | |||
T60657 | (R)-STU104 | TNF , MAPK | |
(R)-STU104 is a novel TAK1-MKK3 protein-protein interaction (PPI) inhibitor that inhibits TNF-α and suppresses the TAK1/MKK3/p38/MnK1/MK2/elF4E signalling pathway by binding to MKK3 and disrupting TAK1 phosphorylation of... | |||
T77404 | Tesnatilimab | IPH-23XX,JNJ-64304500,JNJ 4500 | Others |
Tesnatilimab is a potent humanized IgG4 monoclonal antibody that binds to the immune-activating receptor NKG2D. Tesnatilimab has potential immunomodulatory and anti-inflammatory activity and can be used to study active u... | |||
T77582 | Anti-inflammatory agent 51 | NF-κB | |
Anti-inflammatory agent 51 is an amide/sulfonamide derivative with anti-inflammatory and potentially anti-tumor activity and inhibition of NF-κB activation, which can be used to study acute lung injury and ulcerative col... | |||
T67942 | Antimicrobial agent-21 | MAPK | |
Antimicrobial agent-21 is a potent mitogen activated protein kinase inhibitor with antibacterial, anti-inflammatory and antitumor activity for the treatment of cataracts, ulcerative colitis, meningitis and Kawasaki's dis... | |||
T22963 | McN-A 343 | AChR | |
McN-A 343 is a selective M1 muscarinic agonist known for its ability to stimulate muscarinic transmission in sympathetic ganglia. It has been found to effectively reduce inflammation and oxidative stress in experimental ... | |||
T76741 | Eldelumab | BMS-936557,MDX-1100 | CXCR |
Eldelumab (BMS-936557) is a humanized anti-IP-10 IgG type 1 monoclonal antibody with inhibitory activity against CXCL10.Eldelumab has anti-inflammatory activity and selectively binds to CXCL10 and can be used in the stud... | |||
T5095 | Oxazolone | 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one | Others |
Oxazolone has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory... | |||
T4615 | Balsalazide sodium hydrate | Balsalazide disodium dihydrate,Balsalazide disodium salt dihydrate,Balsalazide disodium | STAT , Interleukin |
Balsalazide sodium hydrate (Balsalazide disodium) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide sodium hydrate is a new 5-aminosalicylic acid (5-ASA) containing prodrug.... | |||
T27142 | Delmitide | Rationally Designed Peptide-58,RDP-1258,RDP5,Allotrap-1258,RDP1258,RDP-5 | |
Delmitide, a TNF-alpha production inhibitor, is used potentially for the treatment of Crohn's disease and ulcerative colitis. | |||
T15211 | Elucaine | Others | |
Elucaine is an antagonist of the muscarinic acetylcholine receptor. It has anti-ulcerative activity. | |||
T68891 | Rivanicline galactarate | ||
Rivanicline galactarate is a Nicotinic Receptor Agonist that may be useful in the treatment of Ulcerative Colitis. | |||
T29013 | HE 3286 | Triolex,HE-3286,HE3286 | |
Triolex, an NF-kB inhibitor, is used potentially for the treatment of rheumatoid arthritis, ulcerative colitis. | |||
T0346L | Camylofin Hydrochloride | Camylofin HCl,Acamylophenine hydrochloride,Acamylophenine HCl,Belosin,Avocan | |
Camylofin HCl is an antispasmodic used in labor treatment and is also used to deliver drug therapy for ulcerative colinitis. | |||
T27077 | CPUY192018 Disodium | CPUY-192018,CPUY192018,CPUY192018disodium,CPUY192018 Na2,CPUY192018-disodium | |
CPUY192018 Disodium is a potent inhibitor of the Keap1-Nrf2 PPI. The inhibition of the Keap1-Nrf2 PPI may be beneficial as a treatment for ulcerative colitis. | |||
T34126 | Prednisolone sodium metazoate | ||
Prednisolone sodium metazoate is used in the treatment of Inflammatory Bowel Disease, Ulcerative Colitis, and GI Disorders. | |||
T62363 | Salazopyridazine | ||
Salazopyridazine is an antibacterial agent that inhibits ulcerative colitis. salazopyridazine can be used in the study of rheumatic diseases. | |||
T27150 | Dersalazine sodium | UR12746,Dersalazine,UR 12746S (sodium salt),UR-12746S (sodium salt),UR-12746 | |
Dersalazine, a PAF antagonist and TNFα inhibitor, is used potentially for the treatment of ulcerative colitis. It showed anti-inflammatory effect in reactivated colitis in rats, as evidenced by a significant reduction in... | |||
T76839 | Visilizumab | ||
Visilizumab, a humanized IgG2 monoclonal antibody with low Fc receptor binding affinity, targets the CD3 epsilon (CD3ε) subunit. It is utilized in research related to ulcerative colitis and Crohn's disease [1]. | |||
T76906 | Anrukinzumab | ||
Anrukinzumab (IMA-638), a humanized anti-IL-13 monoclonal antibody, effectively reduces lung inflammation in cynomolgus monkeys and shows potential in the studies of ulcerative colitis (UC) and asthma [1] [2] [3]. | |||
T77088 | Mirikizumab | ||
Mirikizumab (LY3074828), a humanized IgG4 monoclonal antibody, specifically targets the p19 subunit of interleukin 23. It is currently under research for its potential application in treating ulcerative colitis [1]. | |||
T72406 | Tofacitinib Prodrug-1 | ||
Tofacitinib Prodrug-1 is an effective and oral active prodrug to mitigate the systemic adverse effects of Tofacitinib. Tofacitinib Prodrug-1 can effectively attenuate the oxazolone-induced colitis in mice model with low ... | |||
T72536 | GPR84 antagonist 2 | ||
GPR84 Antagonist 2, a potent and selective GPR84 antagonist (IC 50 = 8.95 nM), demonstrates oral activity and significantly enhances potency in calcium mobilization assays. It effectively inhibits neutrophil and macropha... | |||
T77082 | Melredableukin alfa | ||
Melredableukin alfa (RO-7049665) is a fusion protein comprising a human IgG1-κ and a mutated human interleukin 2 (IL2 mutein) connected by a peptide linker, researched for potential applications in autoimmune hepatitis a... | |||
T63423 | AFM-30a hydrochloride | ||
AFM-30a hydrochloride is a potent and highly selective inhibitor of protein arginine deiminase 2 (PAD2). aFM-30a hydrochloride binds to PAD2 (EC50: 9.5 μM) and also inhibits H3 guanylation (EC50: 0.4 μM). aFM-30a hydroch... | |||
T82231 | HCES2-IN-1 | ||
hCES2-IN-1 (Compound 24) is a reversible, selective inhibitor of the human carboxylesterase 2 (hCES2) enzyme, exhibiting an IC50 of 6.72 μM. This compound diminishes hCES2 levels in vivo and demonstrates efficacy in alle... | |||
T76872 | Neihulizumab | ||
Neihulizumab (ALTB-168), an immune checkpoint agonistic antibody, targets and binds to human CD162 (PSGL-1), resulting in the downregulation of activated T-cells. It is utilized in research aimed at treating steroid-refr... | |||
T63284 | PAD-IN-2 | ||
PAD-IN-2 is a potent inhibitor of pad4 with an IC50 value <1 μM and can be used to study autoimmune diseases and cancers such as rheumatoid arthritis, vasculitis, systemic lupus erythematosus, cutaneous lupus erythematos... | |||
T78508 | Delmitide acetate | RDP-58 acetate | IFNAR |
Delmitide acetate (RDP58) is an orally active d-isomer decapeptide that exhibits potent anti-inflammatory properties. This compound suppresses the production of TNF-α, IFN-γ, and interleukin (IL)-12, while enhancing the ... | |||
T71293 | Nifuroxazide-d4 | ||
Nifuroxazide-d4 is intended for use as an internal standard for the quantification of nifuroxazide by GC- or LC-MS. Nifuroxazide is a nitrofuran antibiotic. It is active against strains of the enteropathogenic bacteria C... | |||
T38052 | CRA-2059 TFA | ||
CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein component in human ma... | |||
T38051 | CRA-2059 hydrochloride | ||
CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein compone... | |||
T36660 | Olsalazine-13C6 | Olsalazine-13C6 | |
Olsalazine-13C6is intended for use as an internal standard for the quantification of olsalazine by GC- or LC-MS. Olsalazine is an orally bioavailable prodrug form of the anti-inflammatory agent 5-aminosalicylic acid that... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T2S0342 | Armillarisin A | Others , Interleukin | |
Armillarisin A enhancing the role of macrophages, inhibiting bacteria growth, improving the protein metabolism, and regulating liver function. | |||
TN1084 | 1,3,5,8-Tetrahydroxyxanthone | Desmethylbellidifolin | Anti-infection |
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity. Dimethylbellidifolin show... | |||
T2718 | Palmatine chloride | Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase | |
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties. | |||
T5S0802 | Palmatine | Berbericinine,Burasaine | Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase |
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,... | |||
T31964 | Glycolithocholic acid | Lithocholic acid glycine conjugate,Lithocholylglycine | Others |
Glycolithocholic acid (Lithocholic acid glycine conjugate) is a glycine conjugate of lithocholic acid. | |||
T0036 | 18β-Glycyrrhetinic acid | Enoxolone,Glycyrrhetin | Dehydrogenase , Endogenous Metabolite |
18β-Glycyrrhetinic acid (Enoxolone) is the major bioactive component of Glycyrrhizae Radix and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties. | |||
T2735 | 5-Acetylsalicylic acid | 5-acetyl-2-hydroxybenzoic acid | Others |
5-Acetylsalicylic acid (5-acetyl-2-hydroxybenzoic acid) has anti-inflammatory effects and can be used to treat inflammatory bowel disease, including ulcerative colitis, inflamed anus or rectum, and to maintain remission ... | |||
T5S1177 | Aloin B | Isobarbaloin | Others |
Aloin B (Isobarbaloin) is an isomer of aloin.1. The extract of A. vera and its active ingredient aloin cause melanin aggregation leading to skin lightening via alpha adrenergic receptor stimulation, the result opens new ... | |||
T75433 | Norisoboldine hydrochloride | ||
Norisoboldine hydrochloride, an orally active aryl hydrocarbon receptor (AhR) agonist and a prominent isoquinoline alkaloid found in Radix Linderae, is utilized for research purposes in the study of Rheumatoid Arthritis ... | |||
T37770 | Taurohyodeoxycholic acid | ||
Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid .1THDCA decreases the size and weight of human gallstonesin vitro. It increases bile flow, biliary cholesterol ... |
カタログ番号 | 製品名 | Species | Expression System |
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TMPY-00493 | IL-19 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the r... | |||
TMPY-03085 | IL-10R beta/IL-10RB Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ... | |||
TMPY-02325 | IL-10R beta/IL-10RB Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ... | |||
TMPY-02324 | IL-10R beta/IL-10RB Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ... | |||
TMPY-01108 | IL-10R beta/IL-10RB Protein, Human, Recombinant (His & hFc) | Human | HEK293 |
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ... | |||
TMPY-01236 | IL-10R beta/IL-10RB Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ... | |||
TMPJ-01152 | MAdCAM-1 Protein, Human, Recombinant (His) | Human | Human Cells |
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an approximately 60 kDa type 1 transmembrane glycoprotein. It is an endothelial cell adhesion molecule that belongs to the immunoglobulin (Ig) superfamily of prote... | |||
TMPY-02952 | SIAE Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of th... | |||
TMPJ-01150 | MAdCAM-1 Protein, Human, Recombinant (Avi & His), Biotinylated | Human | Human Cells |
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an approximately 60 kDa type 1 transmembrane glycoprotein. It is an endothelial cell adhesion molecule that belongs to the immunoglobulin (Ig) superfamily of prote... | |||
TMPJ-01151 | MAdCAM-1 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an approximately 60 kDa type 1 transmembrane glycoprotein. It is an endothelial cell adhesion molecule that belongs to the immunoglobulin (Ig) superfamily of prote... | |||
TMPJ-00698 | BTNL2 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Butyrophilin-like 2 (BTNL2) is a member of the BTN/MOG Ig-superfamily and functions as a negative regulator of immune cell activation. Mouse BTNL2 is type I transmembrane glycoprotein that contains an extracellular domai... | |||
TMPY-03308 | ADAM17 Protein, Rat, Recombinant (His) | Rat | HEK293 |
ADAM17 is a member of the ADAM protein family of disintegrins and metalloproteases. ADAM17 is ubiquitously expressed in the human colon, with increased activity in the colonic mucosa of patients with ulcerative coliti... | |||
TMPY-01033 | IL-32 Protein, Human, Recombinant (isoform alpha, His) | Human | HEK293 |
IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathw... | |||
TMPY-01000 | BVES Protein, Human, Recombinant (GST) | Human | E. coli |
Blood vessel epicardial substance (BVES), or POPDC1, is a tight junction-associated transmembrane protein that modulates epithelial-to-mesenchymal transition (EMT) via junctional signaling pathways. BVES plays a protecti... |
カタログ番号 | 製品名 | ||
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L9810 | Anti-Fibrosis Compound Library | 1155 compounds | |
A unique collection of 1155 potential anti-fibrosis compounds, can be used in HTS and HCS; |