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Search Results for " colitis "

ターゲット

89

阻害剤

19

天然化合物

26

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T22344 Icatibant Acetate Bradykinin Receptor
Icatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema.
T35664 Tetracosactide acetate Others
Cosyntropin (acetate) stimulates the release of corticosteroids such as cortisol from the adrenal gland.
T20615 Olsalazine Dipentium,Salicylic acid Others
Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent.
T9377 ASK1-IN-2 Apoptosis , ASK , MAPK
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can potentially be used as a therapeutic strategy for ulcerative colitis[1].
T10831L Cl-amidine hydrochloride Apoptosis , PAD
Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor (IC50: 5.9 μM for PAD4). Cl-amidine hydrochloride induces apoptosis in cancer cells and it also induces microRNA (miR)-16 in vitro ca...
T30751 Carotegrast methyl AJM300 Integrin
Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.
T64336 Izilendustat HIF/HIF Prolyl-Hydroxylase
Tert-butyl 4-[[1-[(4-chlorophenyl)methyl]-3-hydroxy-2-oxopyridin-4-yl]methyl]piperazine-1-carboxylate inhibit of human recombinant EGLN-1 as substrate after 20 mins by mass spectrophotometric analysis.
T12079 ML604440 Proteasome
ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.
T31482 Diloxanide Diloxanid,RD 3803,RD3803,RD-3803,Diloxanida Parasite
Diloxanide (RD3803) is an endomoeba insecticide. It is considered to be the luminal agent of choice for patients with mild enteroamoebiasis or asymptomatic cysts.
T4084 Sibofimloc VRT-1353385,Antibiotic-202,Antibiotic 202 Antibacterial , Antibiotic
Sibofimloc (Antibiotic-202), an antibiotic compound, is used in treating bacterial infections.
T2171 SEW​2871 SEW2871 S1P Receptor , LPL Receptor
SEW 2871 is an orally available, highly selective S1P1 agonist with an EC50 of 13.8 nM.It reduces the number of lymphocytes in the blood and is used in studies related to diabetes, Alzheimer's disease, liver fibrosis, an...
T2525 Alosetron hydrochloride Lotronex,GR 68755C,GR 68755,GR 68755X 5-HT Receptor
Alosetron hydrochloride (GR 68755) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system,...
T3147 Pyrrolidinedithiocarbamate ammonium PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate NF-κB
Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxide synthase mRNA to prevent induction.
T4602 Hydrocortisone hemisuccinate Hydrocortisone 21-he,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate Glucocorticoid Receptor , Others , Interleukin
Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent.
T28285 P-2281 P 2281,P2281 mTOR
P-2281 is an mTOR inhibitor with anticancer and anti-inflammatory properties.P-2281 inhibits dextran sulfate sodium (DSS)-induced colitis by suppressing T-cell function and is effective in a mouse model of human colitis.
T35898 Izencitinib
Izencitinib (TD-1473) is an orally active, gut-restricted JAK inhibitor with non-selective properties. It is primarily employed in the investigation of ulcerative colitis [1].
T27020 Cilansetron KC-9946,KC9946,DU-123265,DU123265 5-HT Receptor
Cilansetron is an effective and selective 5-HT3 receptor antagonist that can be used for related diseases caused by colitis.
T70084 Dersalazine Dersalazine Free Base IL Receptor , Platelet aggregation
Dersalazine (Dersalazine Free Base), an inhibitor of platelet-activating factor, exerts intestinal anti-inflammatory activity in different rodent types of colitis by down-regulating IL-17 expression, with potential effic...
T0512 Phthalylsulfathiazole Sulfathalidine,N4-Phthalylsulfathiazole Antibacterial , Antibiotic
Phthalylsulfathiazole (N4-Phthalylsulfathiazole) is a broad spectrum antimicrobial agent, used in the treatment of dysentery, colitis, and gastroenteritis.
T2587 Ecabet Sodium TA-2711E,TA-2711 Reactive Oxygen Species , Antibacterial
Ecabet Sodium (TA-2711) is a potential new agent in the management of distal colitis.
T1544 Olsalazine disodium Dipentum,Olsalazine Sodium Others , COX , Antibacterial , Antibiotic
Olsalazine disodium (Dipentum) is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis.
T71691 Pumafentrine BY 343 PDE
Pumafentrine(BY 343) is a dual PDE3/PDE4 inhibitor that reduces clinical scores and TNF expression in experimental colitis in mice.
T9914 Vedolizumab Integrin
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.
T64334 Glycolithocholic acid, sodium salt Others
Glycolithocholic acid sodium salt, the sodium form of Glycolithocholic acid, is a glycine-conjugated secondary bile acid utilized in diagnosing ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH), and primary s...
T10208 A-69412 N-1-(Fur-3-ylethyl)-N-hydroxyurea Lipoxygenase
A-69412 (N-1-(Fur-3-ylethyl)-N-hydroxyurea) is a reversible, specific inhibitor of the hydrophilic 5-lipoxygenase. It has the potential to treat ulcerative colitis and asthma, and possibly other inflammatory and allergic...
T3620 Solcitinib GLPG-0778,GSK-2586184 JAK
Solcitinib (GLPG-0778) (GSK2586184, GLPG0778) is a JAK1 inhibitor. Solcitinib may be potentially used for the treatment of psoriasis, ulcerative colitis, and systemic lupus erythematosus.
T6923 Ozanimod RPC-1063 S1P Receptor , LPL Receptor
Ozanimod (RPC-1063) (RPC1063) is a specific oral S1P Receptor 1 modulator. Ozanimod has been used in trials studying the treatment of Crohn's Disease, Ulcerative Colitis, Multiple Sclerosis, and Relapsing Multiple Sclero...
T77666 MoTPS1-IN-1 Antifungal
MoTPS1-IN-1 is a potent MoTPS1 inhibitor with antifungal and potentially anti-inflammatory activity that acts through interaction with Glu396 and can be used to study ulcerative colitis.
T77404 Tesnatilimab IPH-23XX,JNJ-64304500,JNJ 4500 Others
Tesnatilimab is a potent humanized IgG4 monoclonal antibody that binds to the immune-activating receptor NKG2D. Tesnatilimab has potential immunomodulatory and anti-inflammatory activity and can be used to study active u...
T77582 Anti-inflammatory agent 51 NF-κB
Anti-inflammatory agent 51 is an amide/sulfonamide derivative with anti-inflammatory and potentially anti-tumor activity and inhibition of NF-κB activation, which can be used to study acute lung injury and ulcerative col...
T67942 Antimicrobial agent-21 MAPK
Antimicrobial agent-21 is a potent mitogen activated protein kinase inhibitor with antibacterial, anti-inflammatory and antitumor activity for the treatment of cataracts, ulcerative colitis, meningitis and Kawasaki's dis...
T22963 McN-A 343 AChR
McN-A 343 is a selective M1 muscarinic agonist known for its ability to stimulate muscarinic transmission in sympathetic ganglia. It has been found to effectively reduce inflammation and oxidative stress in experimental ...
T76741 Eldelumab BMS-936557,MDX-1100 CXCR
Eldelumab (BMS-936557) is a humanized anti-IP-10 IgG type 1 monoclonal antibody with inhibitory activity against CXCL10.Eldelumab has anti-inflammatory activity and selectively binds to CXCL10 and can be used in the stud...
T60657 (R)-STU104 TNF , MAPK
(R)-STU104 is a novel TAK1-MKK3 protein-protein interaction (PPI) inhibitor that inhibits TNF-α and suppresses the TAK1/MKK3/p38/MnK1/MK2/elF4E signalling pathway by binding to MKK3 and disrupting TAK1 phosphorylation of...
T5095 Oxazolone 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one Others
Oxazolone has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory...
T4615 Balsalazide sodium hydrate Balsalazide disodium dihydrate,Balsalazide disodium salt dihydrate,Balsalazide disodium STAT , Interleukin
Balsalazide sodium hydrate (Balsalazide disodium) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide sodium hydrate is a new 5-aminosalicylic acid (5-ASA) containing prodrug....
T29013 HE 3286 Triolex,HE-3286,HE3286
Triolex, an NF-kB inhibitor, is used potentially for the treatment of rheumatoid arthritis, ulcerative colitis.
T26680 ATL-801
ATL-801 is anselective antagonist of A2B receptor with herapeutic activity for colitis.
T34831 Teupolioside trans-Lamalboside,Lamiuside A,Teupolioside HTN
Teupolioside is a putatively ameliorates colitis that is isolated from Ajuga reptans.
T27150 Dersalazine sodium UR12746,Dersalazine,UR 12746S (sodium salt),UR-12746S (sodium salt),UR-12746
Dersalazine, a PAF antagonist and TNFα inhibitor, is used potentially for the treatment of ulcerative colitis. It showed anti-inflammatory effect in reactivated colitis in rats, as evidenced by a significant reduction in...
T27077 CPUY192018 Disodium CPUY-192018,CPUY192018,CPUY192018disodium,CPUY192018 Na2,CPUY192018-disodium
CPUY192018 Disodium is a potent inhibitor of the Keap1-Nrf2 PPI. The inhibition of the Keap1-Nrf2 PPI may be beneficial as a treatment for ulcerative colitis.
T27142 Delmitide Rationally Designed Peptide-58,RDP-1258,RDP5,Allotrap-1258,RDP1258,RDP-5
Delmitide, a TNF-alpha production inhibitor, is used potentially for the treatment of Crohn's disease and ulcerative colitis.
T68355 BTZO-15
BTZO-15 is a novel ARE activator, ameliorating DSS- and TNBS-induced colitis in rats.
T34126 Prednisolone sodium metazoate
Prednisolone sodium metazoate is used in the treatment of Inflammatory Bowel Disease, Ulcerative Colitis, and GI Disorders.
T68891 Rivanicline galactarate
Rivanicline galactarate is a Nicotinic Receptor Agonist that may be useful in the treatment of Ulcerative Colitis.
T71314 GL-V9
GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.
T70180 LFS-829
LFS-829 is a a small-molecule antagonist of exportin-1. LFS-829 showed low-range nanomolar activities. Oral administration of LFS-829 can significantly reverse the pathological features of colitis model mice. LFS-829 can...
T12501 Plecanatide acetate Others
Plecanatide acetate is a agonist of guanylate cyclase-C (GC-C) receptor( EC50 of 190 nM in T84 cells), and shows anti-inflammatory activity in models of murine colitis.
T61826 NLRP3-IN-4
NLRP3-IN-4 is a highly efficient and orally bioavailable inhibitor of NLRP3 inflammasome, which exhibits strong anti-inflammatory properties specifically targeted towards colitis.
T70214 BMS-986202
BMS-986202 is a novel Tyk2 inhibitor, binding to Tyk2 JH2, showing efficacies for IL-23-driven acanthosis, anti-CD40-induced colitis, and spontaneous lupus.

Compounds

Icatibant Acetate
T22344
Synonym:
Target: Bradykinin Receptor
Tetracosactide acetate
T35664
Synonym:
Target: Others
Olsalazine
T20615
Synonym: Dipentium,Salicylic acid
Target: Others
ASK1-IN-2
T9377
Synonym:
Target: Apoptosis, ASK, MAPK
Cl-amidine hydrochloride
T10831L
Synonym:
Target: Apoptosis, PAD
Carotegrast methyl
T30751
Synonym: AJM300
Target: Integrin
Izilendustat
T64336
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
ML604440
T12079
Synonym:
Target: Proteasome
Diloxanide
T31482
Synonym: Diloxanid,RD 3803,RD3803,RD-3803,Diloxanida
Target: Parasite
Sibofimloc
T4084
Synonym: VRT-1353385,Antibiotic-202,Antibiotic 202
Target: Antibacterial, Antibiotic
SEW​2871
T2171
Synonym: SEW2871
Target: S1P Receptor, LPL Receptor
Alosetron hydrochloride
T2525
Synonym: Lotronex,GR 68755C,GR 68755,GR 68755X
Target: 5-HT Receptor
Pyrrolidinedithiocarbamate ammonium
T3147
Synonym: PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate
Target: NF-κB
Hydrocortisone hemisuccinate
T4602
Synonym: Hydrocortisone 21-he,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate
Target: Glucocorticoid Receptor, Others, Interleukin
P-2281
T28285
Synonym: P 2281,P2281
Target: mTOR
Izencitinib
T35898
Synonym:
Target:
Cilansetron
T27020
Synonym: KC-9946,KC9946,DU-123265,DU123265
Target: 5-HT Receptor
Dersalazine
T70084
Synonym: Dersalazine Free Base
Target: IL Receptor, Platelet aggregation
Phthalylsulfathiazole
T0512
Synonym: Sulfathalidine,N4-Phthalylsulfathiazole
Target: Antibacterial, Antibiotic
Ecabet Sodium
T2587
Synonym: TA-2711E,TA-2711
Target: Reactive Oxygen Species, Antibacterial
Olsalazine disodium
T1544
Synonym: Dipentum,Olsalazine Sodium
Target: Others, COX, Antibacterial, Antibiotic
Pumafentrine
T71691
Synonym: BY 343
Target: PDE
Vedolizumab
T9914
Synonym:
Target: Integrin
Glycolithocholic acid, sodium salt
T64334
Synonym:
Target: Others
A-69412
T10208
Synonym: N-1-(Fur-3-ylethyl)-N-hydroxyurea
Target: Lipoxygenase
Solcitinib
T3620
Synonym: GLPG-0778,GSK-2586184
Target: JAK
Ozanimod
T6923
Synonym: RPC-1063
Target: S1P Receptor, LPL Receptor
MoTPS1-IN-1
T77666
Synonym:
Target: Antifungal
Tesnatilimab
T77404
Synonym: IPH-23XX,JNJ-64304500,JNJ 4500
Target: Others
Anti-inflammatory agent 51
T77582
Synonym:
Target: NF-κB
Antimicrobial agent-21
T67942
Synonym:
Target: MAPK
McN-A 343
T22963
Synonym:
Target: AChR
Eldelumab
T76741
Synonym: BMS-936557,MDX-1100
Target: CXCR
(R)-STU104
T60657
Synonym:
Target: TNF, MAPK
Oxazolone
T5095
Synonym: 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one
Target: Others
Balsalazide sodium hydrate
T4615
Synonym: Balsalazide disodium dihydrate,Balsalazide disodium salt dihydrate,Balsalazide disodium
Target: STAT, Interleukin
HE 3286
T29013
Synonym: Triolex,HE-3286,HE3286
Target:
ATL-801
T26680
Synonym:
Target:
Teupolioside
T34831
Synonym: trans-Lamalboside,Lamiuside A,Teupolioside HTN
Target:
Dersalazine sodium
T27150
Synonym: UR12746,Dersalazine,UR 12746S (sodium salt),UR-12746S (sodium salt),UR-12746
Target:
CPUY192018 Disodium
T27077
Synonym: CPUY-192018,CPUY192018,CPUY192018disodium,CPUY192018 Na2,CPUY192018-disodium
Target:
Delmitide
T27142
Synonym: Rationally Designed Peptide-58,RDP-1258,RDP5,Allotrap-1258,RDP1258,RDP-5
Target:
BTZO-15
T68355
Synonym:
Target:
Prednisolone sodium metazoate
T34126
Synonym:
Target:
Rivanicline galactarate
T68891
Synonym:
Target:
GL-V9
T71314
Synonym:
Target:
LFS-829
T70180
Synonym:
Target:
Plecanatide acetate
T12501
Synonym:
Target: Others
NLRP3-IN-4
T61826
Synonym:
Target:
BMS-986202
T70214
Synonym:
Target:
1 2
カタログ番号 製品名 別名 ターゲット
T2S0342 Armillarisin A Others , Interleukin
Armillarisin A enhancing the role of macrophages, inhibiting bacteria growth, improving the protein metabolism, and regulating liver function.
T6S1027 Tussilagone Others
1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent for the prevention and treatment of human co...
TN1084 1,3,5,8-Tetrahydroxyxanthone Desmethylbellidifolin Anti-infection
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity. Dimethylbellidifolin show...
T2718 Palmatine chloride Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
T5S0802 Palmatine Berbericinine,Burasaine Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,...
T31964 Glycolithocholic acid Lithocholic acid glycine conjugate,Lithocholylglycine Others
Glycolithocholic acid (Lithocholic acid glycine conjugate) is a glycine conjugate of lithocholic acid.
T8160 EGCG Octaacetate Others , Antibacterial
EGCG Octaacetate, a prodrug of EGCG, is utilized to enhance the stability and bioavailability of EGCG in vivo. It has high efficacy, bioavailability, anti-oxidation, and anti-angiogenesis capacities.
T7908 DL-Methionine Methylsulfonium Chloride Others
DL-Methionine Methylsulfonium Chloride is a natural product, used in the treatment of peptic ulcers, colitis, and gastritis.
T2735 5-Acetylsalicylic acid 5-acetyl-2-hydroxybenzoic acid Others
5-Acetylsalicylic acid (5-acetyl-2-hydroxybenzoic acid) has anti-inflammatory effects and can be used to treat inflammatory bowel disease, including ulcerative colitis, inflamed anus or rectum, and to maintain remission ...
TN1238 3,4-O-Isopropylidene-shikimic acid 3,4-O-Isopropylidene shikimic acid NOS , NO Synthase
3,4-O-Isopropylidene-shikimic acid (3,4-O-Isopropylidene shikimic acid) has significant anti-inflammatory, anti-thrombosis, antioxidant, analgesic effects, it has protective effects on experimental colitis induced by tri...
TN7235 4-methoxylonchocarpin TNF , NF-κB
4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound. 4-methoxylonchocarpin inhibited NF-κB-activated TNF expression by inhibiting the binding of LPS to TLR4 in ma...
TN1370 Allura Red AC Allura Red,CI 16035,FD&C RED NO. 40 Others , Estrogen/progestogen Receptor , Androgen Receptor
Allura Red AC (CI 16035) is a very important food azo dye used in the food, pharmaceutical, paper, cosmetic and textile industries.Allura Red AC promotes susceptibility to experimental colitis via mouse intestinal seroto...
TN5770 Gingerenone A Nrf2
Gingerenone A is an effective Nrf2-Gpx4 activator. It is a small molecule compound isolated from ginger. It has anti-cancer activity, can prolong the cell cycle of cancer cells, and can inhibit dextran sodium sulfate (DS...
T6S1579 Monotropein Monotropeine Others
1. Monotropein (Monotropeine) has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inf...
T5S1177 Aloin B Isobarbaloin Others
Aloin B (Isobarbaloin) is an isomer of aloin.1. The extract of A. vera and its active ingredient aloin cause melanin aggregation leading to skin lightening via alpha adrenergic receptor stimulation, the result opens new ...
T3929 Kaurenoic acid Kauren-19-Oic Acid,kaurenoate,kaur-16-en-18-oic acid Others
Kaurenoic acid (kaurenoate) has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level. Kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part,...
T75433 Norisoboldine hydrochloride
Norisoboldine hydrochloride, an orally active aryl hydrocarbon receptor (AhR) agonist and a prominent isoquinoline alkaloid found in Radix Linderae, is utilized for research purposes in the study of Rheumatoid Arthritis ...
T38330 Collinin
Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Col...
T37770 Taurohyodeoxycholic acid
Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid .1THDCA decreases the size and weight of human gallstonesin vitro. It increases bile flow, biliary cholesterol ...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-02971 CLEC10A Protein, Human, Recombinant (hFc) Human HEK293
CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is ...
TMPY-00493 IL-19 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the r...
TMPK-01011 TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi) Mouse HEK293
TL1A and its functional receptor DR3 are members of the TNF/TNFR superfamilies of proteins.TL1A and DR3 are abundantly localized at inflamed intestinal areas of patients with IBD and mice with experimental ileitis or col...
TMPY-01108 IL-10R beta/IL-10RB Protein, Human, Recombinant (His & hFc) Human HEK293
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ...
TMPK-01137 FAM3D Protein, Human, Recombinant (hFc) Human HEK293
The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (m...
TMPK-01012 TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293
TL1A and its functional receptor DR3 are members of the TNF/TNFR superfamilies of proteins.TL1A and DR3 are abundantly localized at inflamed intestinal areas of patients with IBD and mice with experimental ileitis or col...
TMPK-01013 TL1A/TNFSF15 Protein, Mouse, Recombinant (hFc) Mouse HEK293
TL1A and its functional receptor DR3 are members of the TNF/TNFR superfamilies of proteins.TL1A and DR3 are abundantly localized at inflamed intestinal areas of patients with IBD and mice with experimental ileitis or col...
TMPY-03673 REG3B Protein, Mouse, Recombinant (His) Mouse HEK293
Expression of REG3B was sufficient to inhibit cytokine-induced activation of STAT3 in IECs. The human REG3beta protein, the functional counterpart of mouse REG3B, inhibited STAT3 activity in human 293T cells, and its exp...
TMPY-03085 IL-10R beta/IL-10RB Protein, Rat, Recombinant (hFc) Rat HEK293
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ...
TMPY-02325 IL-10R beta/IL-10RB Protein, Mouse, Recombinant (His) Mouse HEK293
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ...
TMPY-02324 IL-10R beta/IL-10RB Protein, Mouse, Recombinant (hFc) Mouse HEK293
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ...
TMPY-01236 IL-10R beta/IL-10RB Protein, Human, Recombinant (His) Human HEK293
Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 ...
TMPK-01385 CRTAM Protein, Canine, Recombinant (His) Canine HEK293
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of I...
TMPK-00971 CRTAM Protein, Mouse, Recombinant (His) Mouse HEK293
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of I...
TMPY-02459 CLEC10A Protein, Mouse, Recombinant (hFc) Mouse HEK293
CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is ...
TMPY-03172 Argininosuccinate lyase Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric oxide (NO) production. Nitric oxide (NO) plays an established r...
TMPJ-01152 MAdCAM-1 Protein, Human, Recombinant (His) Human Human Cells
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an approximately 60 kDa type 1 transmembrane glycoprotein. It is an endothelial cell adhesion molecule that belongs to the immunoglobulin (Ig) superfamily of prote...
TMPY-00176 FNDC4 Protein, Human, Recombinant (mFc) Human HEK293
FNDC4 acts as an anti-inflammatory factor on macrophages and improves mouse model of induced colitis. FNDC4 could suppress osteoclast formation via NF-kappaB pathway and downregulation of CXCL10. Analysis of binding of F...
TMPY-02405 CLEC10A Protein, Mouse, Recombinant (His) Mouse HEK293
CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is ...
TMPJ-01150 MAdCAM-1 Protein, Human, Recombinant (Avi & His), Biotinylated Human Human Cells
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an approximately 60 kDa type 1 transmembrane glycoprotein. It is an endothelial cell adhesion molecule that belongs to the immunoglobulin (Ig) superfamily of prote...
TMPJ-01151 MAdCAM-1 Protein, Human, Recombinant (hFc) Human Human Cells
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an approximately 60 kDa type 1 transmembrane glycoprotein. It is an endothelial cell adhesion molecule that belongs to the immunoglobulin (Ig) superfamily of prote...
TMPY-02952 SIAE Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Sialate O-acetylesterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. It is widely expressed with high expression in the testis, prostate, and colon. The systematic name of th...
TMPY-03308 ADAM17 Protein, Rat, Recombinant (His) Rat HEK293
ADAM17 is a member of the ADAM protein family of disintegrins and metalloproteases. ADAM17 is ubiquitously expressed in the human colon, with increased activity in the colonic mucosa of patients with ulcerative coliti...
TMPJ-00698 BTNL2 Protein, Mouse, Recombinant (His) Mouse Human Cells
Butyrophilin-like 2 (BTNL2) is a member of the BTN/MOG Ig-superfamily and functions as a negative regulator of immune cell activation. Mouse BTNL2 is type I transmembrane glycoprotein that contains an extracellular domai...
TMPY-01033 IL-32 Protein, Human, Recombinant (isoform alpha, His) Human HEK293
IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathw...
TMPY-01000 BVES Protein, Human, Recombinant (GST) Human E. coli
Blood vessel epicardial substance (BVES), or POPDC1, is a tight junction-associated transmembrane protein that modulates epithelial-to-mesenchymal transition (EMT) via junctional signaling pathways. BVES plays a protecti...
CLEC10A Protein, Human, Recombinant (hFc)
TMPY-02971
Species: Human
Expression System: HEK293
IL-19 Protein, Human, Recombinant (His)
TMPY-00493
Species: Human
Expression System: Baculovirus-Insect Cells
TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi)
TMPK-01011
Species: Mouse
Expression System: HEK293
IL-10R beta/IL-10RB Protein, Human, Recombinant (His & hFc)
TMPY-01108
Species: Human
Expression System: HEK293
FAM3D Protein, Human, Recombinant (hFc)
TMPK-01137
Species: Human
Expression System: HEK293
TL1A/TNFSF15 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-01012
Species: Mouse
Expression System: HEK293
TL1A/TNFSF15 Protein, Mouse, Recombinant (hFc)
TMPK-01013
Species: Mouse
Expression System: HEK293
REG3B Protein, Mouse, Recombinant (His)
TMPY-03673
Species: Mouse
Expression System: HEK293
IL-10R beta/IL-10RB Protein, Rat, Recombinant (hFc)
TMPY-03085
Species: Rat
Expression System: HEK293
IL-10R beta/IL-10RB Protein, Mouse, Recombinant (His)
TMPY-02325
Species: Mouse
Expression System: HEK293
IL-10R beta/IL-10RB Protein, Mouse, Recombinant (hFc)
TMPY-02324
Species: Mouse
Expression System: HEK293
IL-10R beta/IL-10RB Protein, Human, Recombinant (His)
TMPY-01236
Species: Human
Expression System: HEK293
CRTAM Protein, Canine, Recombinant (His)
TMPK-01385
Species: Canine
Expression System: HEK293
CRTAM Protein, Mouse, Recombinant (His)
TMPK-00971
Species: Mouse
Expression System: HEK293
CLEC10A Protein, Mouse, Recombinant (hFc)
TMPY-02459
Species: Mouse
Expression System: HEK293
Argininosuccinate lyase Protein, Human, Recombinant (His & GST)
TMPY-03172
Species: Human
Expression System: Baculovirus-Insect Cells
MAdCAM-1 Protein, Human, Recombinant (His)
TMPJ-01152
Species: Human
Expression System: Human Cells
FNDC4 Protein, Human, Recombinant (mFc)
TMPY-00176
Species: Human
Expression System: HEK293
CLEC10A Protein, Mouse, Recombinant (His)
TMPY-02405
Species: Mouse
Expression System: HEK293
MAdCAM-1 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-01150
Species: Human
Expression System: Human Cells
MAdCAM-1 Protein, Human, Recombinant (hFc)
TMPJ-01151
Species: Human
Expression System: Human Cells
SIAE Protein, Human, Recombinant (His)
TMPY-02952
Species: Human
Expression System: Baculovirus-Insect Cells
ADAM17 Protein, Rat, Recombinant (His)
TMPY-03308
Species: Rat
Expression System: HEK293
BTNL2 Protein, Mouse, Recombinant (His)
TMPJ-00698
Species: Mouse
Expression System: Human Cells
IL-32 Protein, Human, Recombinant (isoform alpha, His)
TMPY-01033
Species: Human
Expression System: HEK293
BVES Protein, Human, Recombinant (GST)
TMPY-01000
Species: Human
Expression System: E. coli
カタログ番号 製品名
L9810 Anti-Fibrosis Compound Library

1155 compounds
A unique collection of 1155 potential anti-fibrosis compounds, can be used in HTS and HCS;