Powder: -20°C for 3 years | In solvent: -80°C for 1 year
K145 hydrochloride is a selective sphk2 inhibitor with substrate competitiveness and oral activity, with IC50 of 4.3 µM and Ki of 6.4 µM. K145 hydrochloride can induce apoptosis and has strong antitumor activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 11,500 | |||
10 mg | 在庫あり | ¥ 16,000 | |||
25 mg | 在庫あり | ¥ 22,500 | |||
50 mg | 在庫あり | ¥ 31,000 |
ターゲット&IC50 | SPHK2:4.30 μM, SPHK2:6.4 µM(Ki) |
分子量 | 384.92 |
分子式 | C18H25ClN2O3S |
CAS No. | 1449240-68-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 125 mg/mL (324.74 mM), Sonication and heating are recommended.
DMSO: 48 mg/mL (124.7 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
K145 hydrochloride 1449240-68-9 Apoptosis GPCR/G Protein S1P Receptor K-145 K 145 ERK K145 Sphingosine kinase K145 Hydrochloride anti-proliferative SphK Akt sphingosine inhibit oral SphK2 K 145 Hydrochloride K-145 Hydrochloride substrate-competitive K-145 hydrochloride Inhibitor antitumor apoptotic S1P inhibitor