Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LY2444296 (FP3FBZ) is an orally active and selective antagonist of kappa opioid receptor(Ki = 1 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 15,500 | |||
10 mg | 在庫あり | ¥ 28,500 | |||
25 mg | 在庫あり | ¥ 50,000 | |||
50 mg | 在庫あり | ¥ 72,500 |
説明 | LY2444296 (FP3FBZ) is an orally active and selective antagonist of kappa opioid receptor(Ki = 1 nM). |
ターゲット&IC50 | κ opioid receptor:ki: ~1 nM |
In vivo | LY2444296 reduces anxiety-like and depressive-like behaviors, and CORT release, in rats tested after chronic extended access cocaine self-administration. In cocaine-naïve adult male Sprague Dawley rats, LY2444296 (3 mg/kg; i.p.) prevents behavioral and neuroendocrine effects caused by U69,593[2]. |
別名 | FP3FBZ |
分子量 | 408.44 |
分子式 | C24H22F2N2O2 |
CAS No. | 1346133-11-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 25.2 mg/mL (61.7 mM), Sonication is recommended.
Methanol: 5 mg/mL (12.24 mM), Sonication is recommended.
DMSO: 60 mg/mL (146.9 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
LY2444296 1346133-11-6 Endocrinology/Hormones GPCR/G Protein Neuroscience Opioid Receptor LY-2444296 LY 2444296 FP3FBZ Inhibitor inhibitor inhibit