store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway. Latanoprost acid can be used in studies about lowering pressure inside the eyes.
説明 | Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway. Latanoprost acid can be used in studies about lowering pressure inside the eyes. |
In vitro | Latanoprost acid (10, 20 μM) reduces the protein expressions of c-fos and NFATc1 thus inhibiting the mature osteoclast formation in BMMs. Latanoprost acid (10μM) and RANKL(50ng/ml) significantly inhibit ERK, p38, AKT and JNK[1]. |
In vivo | Latanoprost acid (i.p.; 20 mg/kg; once a day for 7 days) treatment obviously prevents LPS-induced bone destruction [1]. |
分子量 | 390.51 |
分子式 | C23H34O5 |
CAS No. | 41639-83-2 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27.5 mg/mL (70.42 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Latanoprost acid 41639-83-2 Endocrinology/Hormones GPCR/G Protein GPR Inhibitor inhibitor inhibit