Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Levofloxacin hydrate (Cravit hydrate) is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
50 mg | 在庫あり | ¥ 9,500 | |||
100 mg | 在庫あり | ¥ 11,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Levofloxacin hydrate (Cravit hydrate) is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth. |
細胞研究 | Cell suspension samples (50 mL) (2-5×104 mast cells in each tube for dispersed skin cells or 1 ×105 mast cells in each tube for rat peritoneal cells) in duplicate are equilibrated at 37℃ for 10 min, and then added to polypropylene tubes containing 450 mL test compounds dissolved in Tyrode solution. Histamine release reaction is allowed to proceed for a further 30 min. at the end of which time the reaction is terminated by adding 2 mL ice-cold Tyrode solution and the mixture is centrifuged (450 g for 5 min at 4℃). For determination of total histamine content, mast cells are disrupted in boiling water for 10 min. Histamine concentrations in the resulting supernatant and disrupted cells are determined by the enzyme immunoassay described above. (Only for Reference) |
別名 | Levaquin hydrate, Cravit hydrate, Quixin hydrate, Levofloxacin Hemihydrate, Tavanic hydrate, Iquix hydrate |
分子量 | 370.38 |
分子式 | C18H20FN3O4·1/2H2O |
CAS No. | 138199-71-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 74 mg/mL (199.79 mM)
H2O: 5 mg/mL (13.5 mM)
Ethanol: 10 mg/mL (27 mM)
Methanol: 10 mM
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Levofloxacin hydrate 138199-71-0 DNA Damage/DNA Repair Microbiology/Virology Antibiotic Antibacterial Topoisomerase DNA gyrase inhibit BK Viremia Levofloxacin Hydrate Quixin Hydrate chronic periodontitis Levaquin hydrate Inhibitor Iquix Hydrate Tavanic Hydrate Cravit hydrate Cravit Hydrate DNA/RNA Synthesis Quixin hydrate Levofloxacin Hemihydrate airway inflammation Tavanic hydrate Levofloxacin Bacterial Iquix hydrate Levaquin Hydrate inhibitor