Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MJN110 (Cravatt Reagent) is a potent and selective MAGL inhibitor. Cravatt Reagent inhibits MAGL (IC50 = 9.1 nM). MJN110(Cravatt Reagent) Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 10,000 | |||
10 mg | 在庫あり | ¥ 18,500 | |||
25 mg | 在庫あり | ¥ 41,000 | |||
50 mg | 在庫あり | ¥ 66,000 | |||
100 mg | 在庫あり | ¥ 119,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,000 |
説明 | MJN110 (Cravatt Reagent) is a potent and selective MAGL inhibitor. Cravatt Reagent inhibits MAGL (IC50 = 9.1 nM). MJN110(Cravatt Reagent) Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model. |
ターゲット&IC50 | MAGL:9.1 nM |
In vivo | The Selective Monoacylglycerol Lipase Inhibitor Cravatt Reagent Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model. |
動物実験 | For repeated administration experiments, mice were given vehicle, 0.0818 mg/kg MJN110, 0.469 or 10 mg/kg morphine, or a combination of 0.0818 mg/kg Cravatt Reagent?and 0.469 mg/kg morphine twice?daily for 5.5 days.?Then, mice underwent behavioral testing on day 6.?The combination of 0.0818 mg/kg MJN110 and 0.469 mg/kg morphine produced significant antinociceptive effects. |
別名 | Cravatt Reagent |
分子量 | 462.33 |
分子式 | C22H21Cl2N3O4 |
CAS No. | 1438416-21-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27.5 mg/mL (59.48 mM)
You can also refer to dose conversion for different animals. 詳細
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MJN110 1438416-21-7 Metabolism Lipase MJN 110 MAGL Inhibitor Monoacylglycerol lipase MJN-110 inhibit Cravatt Reagent inhibitor