Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MKC-1 (Ro-31-7453) is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation of the mitotic spindle, which may result in
説明 | MKC-1 (Ro-31-7453) is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation of the mitotic spindle, which may result in |
別名 | Ro-31-7453 |
分子量 | 400.39 |
分子式 | C22H16N4O4 |
CAS No. | 125313-92-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (137.36 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MKC-1 125313-92-0 Apoptosis Cytoskeletal Signaling PI3K/Akt/mTOR signaling Microtubule Associated Akt mTOR inhibit Ro-31-7453 Protein kinase B PKB renal cell cancer Caki-1 Mammalian target of Rapamycin MKC1 MKC 1 orally active Microtubule/Tubulin pancreatic cancer Inhibitor inhibitor