Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 9,000 | |||
25 mg | 在庫あり | ¥ 15,500 | |||
50 mg | 在庫あり | ¥ 22,500 | |||
100 mg | 在庫あり | ¥ 35,500 | |||
500 mg | 在庫あり | ¥ 89,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 10,000 |
説明 | Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation. |
ターゲット&IC50 | PPARγ:17.7 μM (EC50), RXRα:10.4 μM (EC50) |
In vitro | Magnolol shows significant inhibitory activities against Trichophyton mentagrophytes, Microsporium gypseum, Epidermophyton floccosum, Aspergillus niger, Cryptococcus neoformans, and Candida albicans with minimum inhibitory concentrations (MIC) in a range of 25-100 μg/ml. |
植物由来 |
別名 | NSC 293099, 5,5'-Diallyl-2,2'-biphenyldiol |
分子量 | 266.33 |
分子式 | C18H18O2 |
CAS No. | 528-43-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 49 mg/mL (184 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 49 mg/mL (184 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Magnolol 528-43-8 Apoptosis Autophagy DNA Damage/DNA Repair Metabolism Microbiology/Virology NF-Κb PPAR p53 Antibacterial Retinoid Receptor NF-κB inhibit RAR/RXR Retinoic acid receptors NSC 293099 NSC-293099 Retinoid X receptors 5,5'-Diallyl-2,2'-biphenyldiol NSC293099 Inhibitor Peroxisome proliferator-activated receptors Bacterial inhibitor