Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.
説明 | NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner. |
別名 | INF-4E, INF 4E, INF4E |
分子量 | 240.68 |
分子式 | C12H13ClO3 |
CAS No. | 88039-46-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (249.29 mM)
You can also refer to dose conversion for different animals. 詳細
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NLRP3-IN-9 88039-46-7 NF-Κb Immunology/Inflammation NOD inflammasome NOD-like Receptor (NLR) myocardial injury NLRP3 IN 9 caspase-1 dysfunction NLRP3IN9 Inhibitor pyroptosis inhibit NLRP-3-IN-9 INF-4E THP-1 cells INF 4E INF4E inhibitor