Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NSC-319726 (ZMC1), a mutant p53R175 reactivator, suppresses growth of fibroblasts that expresses the p53R175 mutation (IC50 = 8 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
2 mg | 在庫あり | ¥ 7,500 | |||
5 mg | 在庫あり | ¥ 12,000 | |||
10 mg | 在庫あり | ¥ 19,500 | |||
25 mg | 在庫あり | ¥ 36,500 | |||
50 mg | 在庫あり | ¥ 66,000 | |||
100 mg | 在庫あり | ¥ 112,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 13,000 |
説明 | NSC-319726 (ZMC1), a mutant p53R175 reactivator, suppresses growth of fibroblasts that expresses the p53R175 mutation (IC50 = 8 nM). |
ターゲット&IC50 | p53 (R175):8 nM |
キナーゼ試験 | MTS: 5,000 cells of TOV112D cells (5,000 cells/well, in 100 ml culture) are cultured in 96-well plate to reach the 50%–60% confluence on the second day when treated with serial dilutions of the compounds. The growth is measured by MTS reagent and Victor Plate reader instrument after incubation for 3 days. |
細胞研究 | Viability assays are done. The cells (5×104 cells/well, in 1 ml culture) are cultured in a 12-well plate to reach the 50%–60% confluence on the second day when treated with serial dilutions of the compound. The growth is measured by Guava ViaCount reagent and Guava PCA instrument after incubation for 3 days.(Only for Reference) |
分子量 | 234.32 |
分子式 | C11H14N4S |
CAS No. | 71555-25-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 2.3 mg/mL (10 mM)), Heating is recommended.
DMSO: 23.4 mg/mL (100 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ZMC1 71555-25-4 Apoptosis p53 NSC 319726 MDM-2/p53 inhibit ZMC 1 ZMC-1 NSC-319726 NSC319726 Inhibitor inhibitor