store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NV-5138 is a selective and orally active activator of brain mTORC1, with antidepressant effects.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 21,000 | |||
5 mg | 在庫あり | ¥ 52,000 | |||
10 mg | 在庫あり | ¥ 83,500 | |||
25 mg | 在庫あり | ¥ 178,000 | |||
50 mg | 在庫あり | ¥ 282,500 | |||
100 mg | 在庫あり | ¥ 408,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 41,000 |
説明 | NV-5138 is a selective and orally active activator of brain mTORC1, with antidepressant effects. |
In vivo | NV-5138 (160 mg/kg, po, single dose) rapidly increases levels of phospho-mTOR as well as the downstream targets, phospho-p70S6K1, and phosphor-4EB-P1, in synaptosomal preparations of PFC[2].?NV-5138 (80 mg/kg, po, daily for a total of 7 days) also produces antidepressant effects[2]. |
分子量 | 181.18 |
分子式 | C7H13F2NO2 |
CAS No. | 2095886-80-7 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 1.81 mg/ml (10 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
NV-5138 2095886-80-7 PI3K/Akt/mTOR signaling mTOR inhibit Inhibitor NV5138 Mammalian target of Rapamycin NV 5138 inhibitor