Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PARP1-IN-8 (N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide) is an effective inhibito of PARP1 (IC50 = 97 nM).
説明 | PARP1-IN-8 (N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide) is an effective inhibito of PARP1 (IC50 = 97 nM). |
ターゲット&IC50 | PARP1:97 nM |
In vitro | PARP1-IN-8 (0, 0.1, 1, 10 μM; 24, 48 h) showed significantly potent anti-proliferative activity against A549 cells and didn’t display any significant cytotoxicity on HFF cells[1]. |
別名 | N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide |
分子量 | 403.86 |
分子式 | C23H18ClN3O2 |
CAS No. | 836640-15-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (148.57 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PARP1-IN-8 836640-15-4 Chromatin/Epigenetic DNA Damage/DNA Repair PARP poly ADP ribose polymerase phthalazinone inhibit HFF cells Lung adenocarcinoma Inhibitor PARP1 IN 8 PARP1-IN-8 N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide PARP1IN8 A549 cells inhibitor