Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle. 3. Oleandrin has stronger anti-proliferative activity in undifferentiated CaCO-2 cells (IC50, 8.25 nM) , causes an autophagic cell death and altered ERK phosphorylation in undifferentiated.
説明 | 1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle. 3. Oleandrin has stronger anti-proliferative activity in undifferentiated CaCO-2 cells (IC50, 8.25 nM) , causes an autophagic cell death and altered ERK phosphorylation in undifferentiated. |
ターゲット&IC50 | Na+, K+-ATPase:620 nM (IC50) |
植物由来 |
別名 | Neriostene, Folinerin, Foliandrin |
分子量 | 576.72 |
分子式 | C32H48O9 |
CAS No. | 465-16-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: Soluble
Pyridine, Methanol, etc.: Soluble
DMSO: 60 mg/ml (104.04 mM)
You can also refer to dose conversion for different animals. 詳細
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Oleandrin 465-16-7 Apoptosis Membrane transporter/Ion channel Potassium Channel ATPase Sodium Channel Neriostene PBI-05204 Folinerin Na+/K+ ATPase PBI 05204 Inhibitor PBI05204 Sodium potassium pump Foliandrin inhibit inhibitor