Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PP58 is an inhibitor of PDGFR, FGFR and Src family.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 9,000 | |||
5 mg | 在庫あり | ¥ 21,500 | |||
10 mg | 在庫あり | ¥ 34,000 | |||
25 mg | 在庫あり | ¥ 59,000 | |||
50 mg | 在庫あり | ¥ 91,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 22,500 |
説明 | PP58 is an inhibitor of PDGFR, FGFR and Src family. |
In vitro | PP58 inhibits anisomycin-activated p38 in a dose-dependent manner with an IC50 < 10 nM. LPS-stimulated TNF-α production is potently inhibited by PP58 with a cellular IC50 value of 3 nM[1]. |
In vivo | PP58 exhibits some degree of selectivity in vivo[1]. |
分子量 | 456.32 |
分子式 | C22H19Cl2N5O2 |
CAS No. | 212391-58-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 56.3 mg/mL (123.3 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PP58 212391-58-7 Angiogenesis Apoptosis MAPK Tyrosine Kinase/Adaptors PDGFR Src FGFR TNF p38 MAPK PP-58 PP 58 Inhibitor inhibitor inhibit