Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PSI-6130 (R 1656) is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM.
説明 | PSI-6130 (R 1656) is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM. |
ターゲット&IC50 | HCV:0.6 μM |
In vitro | PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM, PSI-6130-TP inhibits HCV replicase with a mean IC50 of 0.34 μM. PSI-6130-TP inhibits recombinant HCV Con1 NS5B on a heteropolymeric RNA template derived from the 3′-end of the negative strand of the HCV genome with an IC50 of 0.13 μM and Ki of 0.023 μM. PSI-6130 is metabolized to two pharmacologically active species in primary human hepatocytes[1]. |
別名 | R 1656 |
分子量 | 259.23 |
分子式 | C10H14FN3O4 |
CAS No. | 817204-33-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (192.88 mM)
You can also refer to dose conversion for different animals. 詳細
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PSI-6130 817204-33-4 Microbiology/Virology Proteases/Proteasome HCV Protease R 1656 inhibit PSI6130 R1656 Hepatitis C virus HCV Inhibitor R-1656 PSI 6130 inhibitor