Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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2 mg | 在庫あり | ¥ 9,000 | |||
5 mg | 在庫あり | ¥ 14,500 | |||
10 mg | 在庫あり | ¥ 18,500 | |||
25 mg | 在庫あり | ¥ 37,500 | |||
50 mg | 在庫あり | ¥ 68,500 | |||
100 mg | 在庫あり | ¥ 107,500 |
説明 | Perifosine (KRX-0401) is an oral-active, alkyl-phosphocholine Akt inhibitor with potential antineoplastic activity. |
ターゲット&IC50 | Akt:4.7 μM |
キナーゼ試験 | Akt kinase assay: MM.1S cells are cultured in the presence or absence of perifosine (5 μM, 6 hours) and then stimulated with IL-6 (20 ng/mL, 10 minutes). In vitro akt kinase assay is then carried out using the Akt Kinase Assay Kit. |
細胞研究 | Cells are incubated in the medium with 10% FCS for 48 hours with indicated concentration of Periosine. Cell viability is determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. (Cell Proliferation Kit I; Roche). The absorbance at 590 nm is recorded using the 96-well plate reader.(Only for Reference) |
別名 | NSC 639966, D21266, KRX-0401 |
分子量 | 461.66 |
分子式 | C25H52NO4P |
CAS No. | 157716-52-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Insoluble
H2O: 10 mM
You can also refer to dose conversion for different animals. 詳細
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Perifosine 157716-52-4 Apoptosis Autophagy Cytoskeletal Signaling PI3K/Akt/mTOR signaling Akt NSC 639966 Protein kinase B Inhibitor NSC639966 D21266 KRX 0401 KRX-0401 KRX0401 inhibit PKB D 21266 NSC-639966 D-21266 inhibitor