Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RIPA-56 is an inhibitor of RIP1
説明 | RIPA-56 is an inhibitor of RIP1 |
ターゲット&IC50 | RIP1:13 nM |
In vivo | In the SIRS mice disease model, RIPA-56?efficiently reduced tumor necrosis factor alpha (TNFα)-induced mortality and multi-organ damage.?Compared to known RIP1 inhibitors, RIPA-56?is potent in both human and murine cells, is much more stable in vivo, and is efficacious in animal model?studies. |
分子量 | 221.3 |
分子式 | C13H19NO2 |
CAS No. | 1956370-21-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (451.88 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
RIPA-56 1956370-21-0 Apoptosis NF-Κb RIP kinase inhibit Receptor-interacting protein kinases RIPA 56 RIPK RIPA56 Inhibitor inhibitor