Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (TNBC) cells
説明 | SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (TNBC) cells |
ターゲット&IC50 | CDK12:98 nM (Kd), CDK12:99 nM, CDK13:4.9 nM (Kd) |
分子量 | 499.36 |
分子式 | C21H20Cl2N10O |
CAS No. | 2387704-62-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.99 mg/mL (10 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SR-4835 2387704-62-1 Apoptosis Cell Cycle/Checkpoint CDK Cyclin dependent kinase inhibit SR 4835 SR4835 Inhibitor inhibitor